CA957281A - Pharmaceutical compositions containing indole-3-acetic acid derivatives as a skeletal muscle stimulant - Google Patents

Pharmaceutical compositions containing indole-3-acetic acid derivatives as a skeletal muscle stimulant

Info

Publication number
CA957281A
CA957281A CA073,876A CA957281DA CA957281A CA 957281 A CA957281 A CA 957281A CA 957281D A CA957281D A CA 957281DA CA 957281 A CA957281 A CA 957281A
Authority
CA
Canada
Prior art keywords
acetic acid
pharmaceutical compositions
compositions containing
acid derivatives
skeletal muscle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA073,876A
Inventor
Nathan N. Share
Cyril S. Mcfarlane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme IA Corp
Original Assignee
Merck Sharp and Dohme IA Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme IA Corp filed Critical Merck Sharp and Dohme IA Corp
Application granted granted Critical
Publication of CA957281A publication Critical patent/CA957281A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA073,876A 1970-02-03 1970-02-03 Pharmaceutical compositions containing indole-3-acetic acid derivatives as a skeletal muscle stimulant Expired CA957281A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA73876 1970-02-03

Publications (1)

Publication Number Publication Date
CA957281A true CA957281A (en) 1974-11-05

Family

ID=4086281

Family Applications (1)

Application Number Title Priority Date Filing Date
CA073,876A Expired CA957281A (en) 1970-02-03 1970-02-03 Pharmaceutical compositions containing indole-3-acetic acid derivatives as a skeletal muscle stimulant

Country Status (8)

Country Link
US (1) US3689657A (en)
BE (1) BE759744A (en)
CA (1) CA957281A (en)
FR (1) FR2081480B1 (en)
GB (1) GB1290795A (en)
IL (1) IL35772A (en)
NL (1) NL7017489A (en)
ZA (1) ZA708144B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0016162D0 (en) * 2000-06-30 2000-08-23 Cancer Res Campaign Tech Indole-3-acetic acid derivatives
US20050203166A1 (en) * 2000-06-30 2005-09-15 Cancer Research Technology Limited Indole-3-acetic acid derivatives
PT1670444E (en) * 2003-10-03 2011-07-29 Veijlen N V Use of indoleacetic acid derivatives which increase the serum igf-1 level for the preparation of a therapeutical composition for treatment of various diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3322786A (en) * 1965-10-07 1967-05-30 Merck & Co Inc 3-indolyl aliphatic acids
FR1512022A (en) * 1966-03-04 1968-02-02 Italiana Sint Spa Process for obtaining indole derivatives, with particular substitution of the hydrogen atom for the nitrogen of the indole ring, by means of the use of phenyl-sodium

Also Published As

Publication number Publication date
IL35772A (en) 1974-06-30
FR2081480B1 (en) 1974-08-30
NL7017489A (en) 1971-08-05
US3689657A (en) 1972-09-05
GB1290795A (en) 1972-09-27
ZA708144B (en) 1972-07-26
FR2081480A1 (en) 1971-12-03
BE759744A (en) 1971-06-02
IL35772A0 (en) 1971-02-25
DE2061985A1 (en) 1971-08-12

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