DK119556B - Fremgangsmåde til fremstilling af 9α-fluor-16β-methyl-derivater af hydrocortison eller prednisolon eller 21-acetater deraf. - Google Patents
Fremgangsmåde til fremstilling af 9α-fluor-16β-methyl-derivater af hydrocortison eller prednisolon eller 21-acetater deraf.Info
- Publication number
- DK119556B DK119556B DK5459AA DK5459A DK119556B DK 119556 B DK119556 B DK 119556B DK 5459A A DK5459A A DK 5459AA DK 5459 A DK5459 A DK 5459A DK 119556 B DK119556 B DK 119556B
- Authority
- DK
- Denmark
- Prior art keywords
- prednisolone
- hydrocortisone
- acetates
- fluoro
- preparation
- Prior art date
Links
- JYGXADMDTFJGBT-VWUMJDOOSA-N Hydrocortisone Natural products O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 title 1
- 229960000890 hydrocortisone Drugs 0.000 title 1
- 229960005205 prednisolone Drugs 0.000 title 1
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/832—Bacillus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72239058A | 1958-03-19 | 1958-03-19 | |
| US1198360A | 1960-03-01 | 1960-03-01 | |
| US11984A US3418316A (en) | 1958-03-19 | 1960-03-01 | Novel 16-alkylene steroids and processes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK119556B true DK119556B (da) | 1971-01-25 |
Family
ID=27359550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK5459AA DK119556B (da) | 1958-03-19 | 1959-01-07 | Fremgangsmåde til fremstilling af 9α-fluor-16β-methyl-derivater af hydrocortison eller prednisolon eller 21-acetater deraf. |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US3461144A (da) |
| CH (1) | CH390912A (da) |
| DE (5) | DE1418318A1 (da) |
| DK (1) | DK119556B (da) |
| GB (1) | GB906443A (da) |
| SE (1) | SE301799B (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1244604A (en) * | 1967-08-25 | 1971-09-02 | Organon Labor Ltd | Substituted methylene steroids and their preparation |
| FR2408622A1 (fr) * | 1977-05-06 | 1979-06-08 | Roussel Uclaf | Nouveaux derives du pregn 4-ene, leur procede de preparation et leur application comme medicament |
| US4568492A (en) * | 1984-09-14 | 1986-02-04 | The Upjohn Company | Δ16-20-Keto steroid conversion to 17α-hydroxy-20-keto steroids |
| CN101417912B (zh) * | 2008-11-10 | 2012-11-14 | 湖南玉新药业有限公司 | 制备倍他米松醋酸酯的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2705233A (en) * | 1950-05-29 | 1955-03-29 | Glidden Co | 16, 17-oxido-pregnane-3alpha-ol-3, 20-dione |
| GB744237A (en) * | 1951-05-25 | 1956-02-01 | Syntex Sa | Cyclopentanophenanthrene compounds and process for the production thereof |
-
1958
- 1958-12-11 CH CH6717958A patent/CH390912A/de unknown
- 1958-12-18 GB GB40932/58A patent/GB906443A/en not_active Expired
-
1959
- 1959-01-07 DK DK5459AA patent/DK119556B/da unknown
- 1959-03-13 DE DE19591418318 patent/DE1418318A1/de active Pending
- 1959-03-13 DE DEM47324A patent/DE1193941B/de active Pending
- 1959-03-13 DE DEM47325A patent/DE1146879B/de active Pending
- 1959-03-13 DE DEM47326A patent/DE1147581B/de active Pending
- 1959-03-13 DE DE19591543247 patent/DE1543247A1/de active Pending
-
1960
- 1960-03-01 US US11983A patent/US3461144A/en not_active Expired - Lifetime
- 1960-03-01 US US11984A patent/US3418316A/en not_active Expired - Lifetime
-
1962
- 1962-12-03 SE SE1299762A patent/SE301799B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE1147581B (de) | 1963-04-25 |
| DE1543247A1 (de) | 1969-12-11 |
| DE1146879B (de) | 1963-04-11 |
| US3461144A (en) | 1969-08-12 |
| GB906443A (en) | 1962-09-19 |
| CH390912A (de) | 1965-04-30 |
| US3418316A (en) | 1968-12-24 |
| SE301799B (sv) | 1968-06-24 |
| DE1193941B (de) | 1965-06-03 |
| DE1418318A1 (de) | 1969-03-27 |
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