DK1194035T3 - Delmængder af myeloide progenitorceller i pattedyr - Google Patents
Delmængder af myeloide progenitorceller i pattedyrInfo
- Publication number
- DK1194035T3 DK1194035T3 DK00946928T DK00946928T DK1194035T3 DK 1194035 T3 DK1194035 T3 DK 1194035T3 DK 00946928 T DK00946928 T DK 00946928T DK 00946928 T DK00946928 T DK 00946928T DK 1194035 T3 DK1194035 T3 DK 1194035T3
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- progenitor
- myeloid
- lineages
- erythroid
- Prior art date
Links
- 210000003643 myeloid progenitor cell Anatomy 0.000 title abstract 4
- 210000004027 cell Anatomy 0.000 abstract 3
- 210000003311 CFU-EM Anatomy 0.000 abstract 2
- 210000003714 granulocyte Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 101001043809 Homo sapiens Interleukin-7 receptor subunit alpha Proteins 0.000 abstract 1
- 108010038498 Interleukin-7 Receptors Proteins 0.000 abstract 1
- 102000010782 Interleukin-7 Receptors Human genes 0.000 abstract 1
- 102100021593 Interleukin-7 receptor subunit alpha Human genes 0.000 abstract 1
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 abstract 1
- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 210000004443 dendritic cell Anatomy 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000000267 erythroid cell Anatomy 0.000 abstract 1
- 230000000925 erythroid effect Effects 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 210000003593 megakaryocyte Anatomy 0.000 abstract 1
- 210000001616 monocyte Anatomy 0.000 abstract 1
- 210000000066 myeloid cell Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000000130 stem cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/14—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/145—Thrombopoietin [TPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/26—Flt-3 ligand (CD135L, flk-2 ligand)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Developmental Biology & Embryology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14142199P | 1999-06-29 | 1999-06-29 | |
| PCT/US2000/018047 WO2001000019A1 (en) | 1999-06-29 | 2000-06-29 | Mammalian myeloid progenitor cell subsets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1194035T3 true DK1194035T3 (da) | 2008-01-28 |
Family
ID=22495616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00946928T DK1194035T3 (da) | 1999-06-29 | 2000-06-29 | Delmængder af myeloide progenitorceller i pattedyr |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6465247B1 (da) |
| EP (1) | EP1194035B1 (da) |
| AT (1) | ATE373421T1 (da) |
| AU (1) | AU774876B2 (da) |
| CA (1) | CA2375974C (da) |
| DE (1) | DE60036470T2 (da) |
| DK (1) | DK1194035T3 (da) |
| ES (1) | ES2293912T3 (da) |
| WO (1) | WO2001000019A1 (da) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6761883B2 (en) * | 1999-06-29 | 2004-07-13 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian myeloid progenitor cell subsets |
| DK1194035T3 (da) * | 1999-06-29 | 2008-01-28 | Univ Leland Stanford Junior | Delmængder af myeloide progenitorceller i pattedyr |
| EP1536688B1 (en) * | 2002-09-13 | 2011-12-28 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian megakaryocyte progenitor cell |
| JP2006512060A (ja) * | 2002-11-07 | 2006-04-13 | ザ ユニヴァーシティ オヴ シカゴ | ヒト幹細胞の材料および方法 |
| US20050003534A1 (en) * | 2002-11-07 | 2005-01-06 | Eliezer Huberman | Human stem cell materials and methods |
| US20040136973A1 (en) * | 2002-11-07 | 2004-07-15 | Eliezer Huberman | Human stem cell materials and methods |
| WO2005057172A2 (en) * | 2003-12-05 | 2005-06-23 | The Board Of Trustees Of The Leland Stanford Junior University | Identification, isolation and elimination of cancer stem cells |
| US7622108B2 (en) | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
| CN101080486B (zh) | 2004-04-23 | 2012-05-16 | 佰欧益股份有限公司 | 多谱系祖细胞 |
| WO2005113751A1 (en) | 2004-05-14 | 2005-12-01 | Becton, Dickinson And Company | Cell culture environments for the serum-free expansion of mesenchymal stem cells |
| KR101544292B1 (ko) * | 2004-10-25 | 2015-08-12 | 셀러랜트 세라퓨틱스 인코퍼레이티드 | 골수형 세포군의 증량 방법 및 그의 용도 |
| US7811815B2 (en) * | 2004-11-15 | 2010-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic uses of allogeneic myeloid progenitor cells |
| US20090191202A1 (en) * | 2005-09-29 | 2009-07-30 | Jamieson Catriona Helen M | Methods for manipulating phagocytosis mediated by CD47 |
| US7514229B2 (en) * | 2005-09-29 | 2009-04-07 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for diagnosing and evaluating treatment of blood disorders |
| US9388382B2 (en) * | 2005-10-05 | 2016-07-12 | The Board Of Trustees Of The University Of Illinois | Isolation of CD14 negative, CD45 positive and CD117 positive embryonic-like stem cells free of monocytes from human umbilical cord blood mononuclear cells |
| CN101421393B (zh) | 2006-02-14 | 2013-08-14 | 塞勒兰特治疗公司 | 提高造血干细胞植入的方法和组合物 |
| EP2422803A3 (en) | 2006-03-07 | 2013-03-13 | Geeta Shroff | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation |
| CA2646491A1 (en) | 2006-04-17 | 2007-10-25 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
| CA2666789C (en) * | 2006-10-18 | 2016-11-22 | Yong Zhao | Embryonic-like stem cells derived from adult human peripheral blood and methods of use |
| US20100287631A1 (en) * | 2006-11-02 | 2010-11-11 | The Regents Of The University Of California | Wnt pathway mutations in cancer stem cells |
| PT3043181T (pt) | 2008-01-15 | 2020-06-17 | Univ Leland Stanford Junior | Marcadores de células estaminais de leucemia mielóide aguda |
| US20090191164A1 (en) * | 2008-01-15 | 2009-07-30 | Ravindra Majeti | Human hematopoietic multipotent progenitor cells |
| US11072655B2 (en) | 2008-01-15 | 2021-07-27 | The Board Of Trustees Of The Leland Stanford Junior University | Markers of acute myeloid leukemia stem cells |
| CA3054220C (en) | 2008-01-15 | 2022-10-11 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for manilpulating phagocytosis mediated by cd47 |
| WO2011059972A1 (en) * | 2009-11-10 | 2011-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Cell surface marker expression in hematopoietic stem cells and progenitors for the diagnosis, prognosis, and treatment of myelodysplastic syndromes |
| ES2616010T3 (es) | 2010-05-14 | 2017-06-09 | The Board Of Trustees Of The Leland Stanford Junior University | Anticuerpos monoclonales humanizados y quiméricos a CD47 |
| WO2012048298A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions |
| WO2015073913A1 (en) | 2013-11-16 | 2015-05-21 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
| US11008547B2 (en) | 2014-03-25 | 2021-05-18 | Terumo Bct, Inc. | Passive replacement of media |
| CN106715676A (zh) | 2014-09-26 | 2017-05-24 | 泰尔茂比司特公司 | 按计划供养 |
| EP3000483A1 (en) * | 2014-09-29 | 2016-03-30 | Charité - Universitätsmedizin Berlin | Means and methods for the diagnosis and treatment of neurodegenerative diseases |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| IL296410A (en) | 2015-11-27 | 2022-11-01 | Cartherics Pty Ltd | Genetically modified stem cells and their uses |
| CN109415696A (zh) | 2016-05-25 | 2019-03-01 | 泰尔茂比司特公司 | 细胞扩增 |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| EP3601521A2 (en) | 2017-03-31 | 2020-02-05 | Terumo BCT, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| WO2020033791A1 (en) | 2018-08-09 | 2020-02-13 | Verseau Therapeutics, Inc. | Oligonucleotide compositions for targeting ccr2 and csf1r and uses thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4422667A1 (de) | 1994-06-30 | 1996-01-04 | Boehringer Ingelheim Int | Verfahren zur Herstellung und Züchtung hämatopoetischer Vorläuferzellen |
| US5821108A (en) * | 1995-04-07 | 1998-10-13 | The Board Of Trustees Of The Leland Stanford Junior University | Enrichment for a thymocyte subset having progenitor cell activity using c-kit as a selection marker |
| DE19600589C1 (de) | 1996-01-10 | 1997-01-16 | Univ Eberhard Karls | Antikörper A3C6E2 |
| US5843633A (en) | 1996-04-26 | 1998-12-01 | Amcell Corporation | Characterization of a human hematopoietic progenitor cell antigen |
| US6908763B1 (en) * | 1997-08-22 | 2005-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian common lymphoid progenitor cell |
| DK1194035T3 (da) * | 1999-06-29 | 2008-01-28 | Univ Leland Stanford Junior | Delmængder af myeloide progenitorceller i pattedyr |
-
2000
- 2000-06-29 DK DK00946928T patent/DK1194035T3/da active
- 2000-06-29 US US09/607,529 patent/US6465247B1/en not_active Expired - Lifetime
- 2000-06-29 DE DE60036470T patent/DE60036470T2/de not_active Expired - Lifetime
- 2000-06-29 EP EP00946928A patent/EP1194035B1/en not_active Expired - Lifetime
- 2000-06-29 AU AU60612/00A patent/AU774876B2/en not_active Ceased
- 2000-06-29 CA CA2375974A patent/CA2375974C/en not_active Expired - Fee Related
- 2000-06-29 AT AT00946928T patent/ATE373421T1/de not_active IP Right Cessation
- 2000-06-29 WO PCT/US2000/018047 patent/WO2001000019A1/en active IP Right Grant
- 2000-06-29 ES ES00946928T patent/ES2293912T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1194035A4 (en) | 2003-07-02 |
| CA2375974A1 (en) | 2001-01-04 |
| DE60036470D1 (de) | 2007-10-31 |
| US6465247B1 (en) | 2002-10-15 |
| WO2001000019A1 (en) | 2001-01-04 |
| EP1194035A1 (en) | 2002-04-10 |
| ATE373421T1 (de) | 2007-10-15 |
| DE60036470T2 (de) | 2008-06-19 |
| ES2293912T3 (es) | 2008-04-01 |
| AU774876B2 (en) | 2004-07-08 |
| CA2375974C (en) | 2010-11-02 |
| EP1194035B1 (en) | 2007-09-19 |
| AU6061200A (en) | 2001-01-31 |
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