DK1189615T3 - Endoparasiticide synergistic combination containing cyclic depsipeptides and piperazines - Google Patents
Endoparasiticide synergistic combination containing cyclic depsipeptides and piperazinesInfo
- Publication number
- DK1189615T3 DK1189615T3 DK00940235T DK00940235T DK1189615T3 DK 1189615 T3 DK1189615 T3 DK 1189615T3 DK 00940235 T DK00940235 T DK 00940235T DK 00940235 T DK00940235 T DK 00940235T DK 1189615 T3 DK1189615 T3 DK 1189615T3
- Authority
- DK
- Denmark
- Prior art keywords
- piperazines
- endoparasiticide
- depsipeptides
- cyclic depsipeptides
- containing cyclic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
The invention relates to the use of piperazines for potentiating the endoparasiticidal action of cyclic depsipeptides in endoparasiticidal agents. Said depsipeptides are comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms. The invention also relates to agents of this type and to the use of piperazines and cyclic depsipeptides, said depsipeptides being comprised of amino acids and hydroxycarboxylic acids serving as ring structural elements and having 24 ring atoms, in order to produce endoparasiticidal agents.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19921887A DE19921887A1 (en) | 1999-05-12 | 1999-05-12 | Synergistic ectoparasiticide combination for use in human or veterinary medicine, comprising cyclic depsipeptide and piperazine compound as potentiating agent |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1189615T3 true DK1189615T3 (en) | 2004-06-07 |
Family
ID=7907825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK00940235T DK1189615T3 (en) | 1999-05-12 | 2000-05-04 | Endoparasiticide synergistic combination containing cyclic depsipeptides and piperazines |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP1189615B1 (en) |
JP (1) | JP2002544224A (en) |
KR (1) | KR100704717B1 (en) |
CN (1) | CN1224391C (en) |
AT (1) | ATE258795T1 (en) |
AU (1) | AU768910B2 (en) |
BR (1) | BR0010499A (en) |
CA (1) | CA2373827C (en) |
CZ (1) | CZ300782B6 (en) |
DE (2) | DE19921887A1 (en) |
DK (1) | DK1189615T3 (en) |
ES (1) | ES2211558T3 (en) |
HK (1) | HK1047228B (en) |
HR (1) | HRP20010918B1 (en) |
HU (1) | HUP0201201A3 (en) |
MX (1) | MXPA01011455A (en) |
NO (1) | NO328870B1 (en) |
PL (1) | PL200951B1 (en) |
PT (1) | PT1189615E (en) |
RS (1) | RS50169B (en) |
RU (1) | RU2250779C2 (en) |
SK (1) | SK285494B6 (en) |
TR (2) | TR200103240T2 (en) |
UA (1) | UA72520C2 (en) |
WO (1) | WO2000069425A2 (en) |
ZA (1) | ZA200108238B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10008128A1 (en) * | 2000-02-22 | 2001-08-23 | Bayer Ag | Endoparasiticide composition effective on topical administration, comprises solution of depsipeptide in solvent such as 1,2-isopropylidene-glycerol |
DE10358525A1 (en) * | 2003-12-13 | 2005-07-07 | Bayer Healthcare Ag | Endoparasiticides Means for topical application |
KR101671325B1 (en) * | 2015-01-09 | 2016-11-02 | 한국생명공학연구원 | Novel cyclic depsipeptide-based compound, separation method thereof, and antibacterial pharmaceutical composition containing the same as an active ingredient |
LT3298027T (en) | 2015-05-20 | 2021-08-10 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
SG11201805368YA (en) * | 2015-12-28 | 2018-07-30 | Merial Inc | Anthelmintic depsipeptide compounds |
WO2018093920A1 (en) | 2016-11-16 | 2018-05-24 | Merial, Inc. | Anthelmintic depsipeptide compounds |
US20230339874A1 (en) * | 2020-09-11 | 2023-10-26 | The Governing Council Of The University Of Toronto | Piperazinyl compounds and methods for treating nematode infections |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA842571B (en) * | 1983-04-07 | 1985-11-27 | Merck & Co Inc | Novel synergistic antiparasitic combinations |
JPS6471865A (en) * | 1987-09-11 | 1989-03-16 | Nichibai Boeki Kk | 1-alkylcarbamoyl-4-methylpiperazine derivative |
NO176766C (en) * | 1989-02-07 | 1995-05-24 | Meiji Seika Kaisha | Process for the preparation of a compound having anthelmintic activity |
AU686222B2 (en) * | 1993-09-06 | 1998-02-05 | Astellas Pharma Inc. | Cyclodepsipeptide compound |
DE4400464A1 (en) * | 1994-01-11 | 1995-07-13 | Bayer Ag | Endoparasiticidal agents |
DE19520275A1 (en) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Endoparasiticidal agents |
AU6860296A (en) * | 1995-09-07 | 1997-03-27 | Pharmacia & Upjohn Company | Cycloanthelmintic inhibitors |
AU6229898A (en) * | 1997-02-19 | 1998-09-09 | Bayer Aktiengesellschaft | Derivatives of cyclodepsipeptide, pf1022 substance |
JP2002502398A (en) * | 1997-06-04 | 2002-01-22 | バイエル・アクチエンゲゼルシヤフト | Desoxycyclodepsipeptide and its use for controlling endoparasites |
US6288038B1 (en) * | 1998-08-04 | 2001-09-11 | Nisshin Seifun Group Inc. | Depsipeptide derivatives bearing piperazinone rings |
-
1999
- 1999-05-12 DE DE19921887A patent/DE19921887A1/en not_active Withdrawn
-
2000
- 2000-04-05 UA UA2001128532A patent/UA72520C2/en unknown
- 2000-05-04 RS YUP-805/01A patent/RS50169B/en unknown
- 2000-05-04 AU AU55237/00A patent/AU768910B2/en not_active Ceased
- 2000-05-04 RU RU2001133380/15A patent/RU2250779C2/en not_active IP Right Cessation
- 2000-05-04 TR TR2001/03240T patent/TR200103240T2/en unknown
- 2000-05-04 JP JP2000617884A patent/JP2002544224A/en active Pending
- 2000-05-04 MX MXPA01011455A patent/MXPA01011455A/en active IP Right Grant
- 2000-05-04 KR KR1020017013555A patent/KR100704717B1/en not_active IP Right Cessation
- 2000-05-04 CA CA002373827A patent/CA2373827C/en not_active Expired - Fee Related
- 2000-05-04 ES ES00940235T patent/ES2211558T3/en not_active Expired - Lifetime
- 2000-05-04 PL PL351376A patent/PL200951B1/en not_active IP Right Cessation
- 2000-05-04 WO PCT/EP2000/004014 patent/WO2000069425A2/en active IP Right Grant
- 2000-05-04 EP EP00940235A patent/EP1189615B1/en not_active Expired - Lifetime
- 2000-05-04 DK DK00940235T patent/DK1189615T3/en active
- 2000-05-04 TR TR2004/01875T patent/TR200401875T2/en unknown
- 2000-05-04 BR BR0010499-0A patent/BR0010499A/en not_active Application Discontinuation
- 2000-05-04 CZ CZ20014060A patent/CZ300782B6/en not_active IP Right Cessation
- 2000-05-04 AT AT00940235T patent/ATE258795T1/en active
- 2000-05-04 HU HU0201201A patent/HUP0201201A3/en unknown
- 2000-05-04 CN CNB00807450XA patent/CN1224391C/en not_active Expired - Fee Related
- 2000-05-04 SK SK1626-2001A patent/SK285494B6/en not_active IP Right Cessation
- 2000-05-04 DE DE50005213T patent/DE50005213D1/en not_active Expired - Lifetime
- 2000-05-04 PT PT00940235T patent/PT1189615E/en unknown
-
2001
- 2001-10-08 ZA ZA200108238A patent/ZA200108238B/en unknown
- 2001-11-05 NO NO20015398A patent/NO328870B1/en not_active IP Right Cessation
- 2001-12-11 HR HR20010918A patent/HRP20010918B1/en not_active IP Right Cessation
-
2002
- 2002-11-26 HK HK02108544.2A patent/HK1047228B/en not_active IP Right Cessation
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