DK117484D0 - 1- (2-CARBETHOXY-4-BENZALKYLAMIDO-PHENOXY) -3-AMINO-2-PROPANOLS AND PROCEDURES FOR PREPARING THEREOF AND THE USE OF THE COMPOUNDS AS MEDICINAL PRODUCTS - Google Patents

1- (2-CARBETHOXY-4-BENZALKYLAMIDO-PHENOXY) -3-AMINO-2-PROPANOLS AND PROCEDURES FOR PREPARING THEREOF AND THE USE OF THE COMPOUNDS AS MEDICINAL PRODUCTS

Info

Publication number
DK117484D0
DK117484D0 DK1174/84A DK117484A DK117484D0 DK 117484 D0 DK117484 D0 DK 117484D0 DK 1174/84 A DK1174/84 A DK 1174/84A DK 117484 A DK117484 A DK 117484A DK 117484 D0 DK117484 D0 DK 117484D0
Authority
DK
Denmark
Prior art keywords
branched
atom
formula
lower alkyl
alkyl radical
Prior art date
Application number
DK1174/84A
Other languages
Danish (da)
Other versions
DK117484A (en
Inventor
Etienne Bouley
Jean Lacrampe
Jean-Marie Teulon
Original Assignee
Carpibem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8304150A external-priority patent/FR2542737B1/en
Priority claimed from FR8318509A external-priority patent/FR2555169B2/en
Application filed by Carpibem filed Critical Carpibem
Publication of DK117484D0 publication Critical patent/DK117484D0/en
Publication of DK117484A publication Critical patent/DK117484A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Claims for the Contracting States : BE CH DE FR GB IT LI LU NL SE Compounds characterized in that they respond to formula : see diagramm : EP0122827,P20,F2 in which : - R and R' may each designate an atom of hydrogen, an atom of halogen, a nitro group or alkyl or alkoxy radicals with C1-C5, branched or not, or a SCH3 or CF3 group ; - R1 represents a lower alkyl radical with 1 to 5 carbon atoms, branched or not ; - R2 represents a lower alkyl radical with 1 to 5 carbon atoms, branched or not ; and - n designates an integer less than 5. 1. Claims for the Contracting State : AT A process for preparing novel compounds responding to formula see diagramm : EP0122827,P21,F2 in which : - R and R' may each designate an atom of hydrogen, an atom of halogen, a nitro group or alkyl or alkoxy radicals with C1-C5, branched or not, or a SCH3 or CF3 group ; - R1 represents a lower alkyl radical with C1 -C5 , branched or not ; - R2 represents a lower alkyl radical with C1 -C5 , branched or not ; and - n designates an integer less than 5, characterized in that said process comprises the step of reacting a base of formula NH2 -R2 where R2 is as defined hereinabove, on a compound of formula (II) without solvent or in a conventional organic solvent such as alcohols, at a temperature of between 20 degrees C and 150 degrees C, see diagramm : EP0122827,P21,F3 R, R', R1 and n being as defined hereinabove.
DK117484A 1983-03-14 1984-02-28 1- (2-CARBETHOXY-4-BENZALKYLAMIDO-PHENOXY) -3-AMINO-2-PROPANOLS AND PROCEDURES FOR PREPARING THEREOF AND THE USE OF THE COMPOUNDS AS MEDICINAL PRODUCTS DK117484A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8304150A FR2542737B1 (en) 1983-03-14 1983-03-14 NOVELS (CARBETHOXY-2 BENZALKYLAMIDO-4 PHENOXY) -1 AMINO-3 PROPANOLS-2, THEIR PREPARATIONS AND THEIR THERAPEUTIC USES
FR8318509A FR2555169B2 (en) 1983-11-21 1983-11-21 NOVEL (CARBETHOXY-2 BENZALKYLAMIDO-4 PHENOXYL) -1 AMINO-3 PROPANOLS-2, THEIR PREPARATIONS AND THEIR THERAPEUTIC USES

Publications (2)

Publication Number Publication Date
DK117484D0 true DK117484D0 (en) 1984-02-28
DK117484A DK117484A (en) 1984-09-15

Family

ID=26223333

Family Applications (1)

Application Number Title Priority Date Filing Date
DK117484A DK117484A (en) 1983-03-14 1984-02-28 1- (2-CARBETHOXY-4-BENZALKYLAMIDO-PHENOXY) -3-AMINO-2-PROPANOLS AND PROCEDURES FOR PREPARING THEREOF AND THE USE OF THE COMPOUNDS AS MEDICINAL PRODUCTS

Country Status (12)

Country Link
EP (1) EP0122827B1 (en)
KR (1) KR910002945B1 (en)
AT (1) ATE20879T1 (en)
AU (1) AU567332B2 (en)
CA (1) CA1218378A (en)
DE (1) DE3460323D1 (en)
DK (1) DK117484A (en)
ES (1) ES530503A0 (en)
GR (1) GR81821B (en)
IE (1) IE57094B1 (en)
PH (1) PH19184A (en)
PT (1) PT78238B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617020A1 (en) * 1992-04-02 1994-09-28 Shudo, Koichi, Prof. Dr. Carboxylic acid derivatives having retinoic acid-like activity
JP3854154B2 (en) * 2000-04-19 2006-12-06 ニューロテック カンパニー リミテッド Compounds, compositions and methods for preventing neurodegeneration resulting from acute and chronic damage to the central nervous system
US6573402B1 (en) 2000-04-20 2003-06-03 Neurotech Co., Ltd. Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system
EP1551793B1 (en) 2002-06-19 2016-01-20 AmKor Pharma, Inc. Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same
KR101333753B1 (en) 2006-04-13 2013-11-28 주식회사 아라온테크 Pharmaceutical composition for treating or preventing degenerative and inflammatory diseases
KR100852962B1 (en) 2007-11-12 2008-08-20 주식회사 뉴로테크 Manufacturing method of 2-hydroxy-5-phenylalkylaminobenzoic acid derivatives and their salts
CA2708804C (en) 2007-12-14 2016-01-12 3M Innovative Properties Company Fiber aggregate
EA021092B1 (en) 2007-12-14 2015-04-30 Шлюмбергер Текнолоджи Б.В. Method of treating subterranean wells using changeable additives
MX2010006456A (en) 2007-12-14 2010-09-28 Schlumberger Technology Bv Proppants and uses thereof.
KR101204108B1 (en) * 2009-02-09 2012-11-22 주식회사 지엔티파마 Medicinal use of 5-benzylaminosalicylic acid derivative or its salt

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852468A (en) * 1967-02-27 1974-12-03 Ici Ltd Alkanolamine derivatives as {62 -adrenergic blocking agents
MX158644A (en) * 1982-07-20 1989-02-21 Menarini Sas PROCEDURE FOR PREPARING A DERIVATIVE 1-ALKYLAMINE-3- (4 (P-ALKYL OXYBENZAMIDE) -PHENOXY) -2PROPANOL

Also Published As

Publication number Publication date
DE3460323D1 (en) 1986-08-28
EP0122827B1 (en) 1986-07-23
DK117484A (en) 1984-09-15
ES8504681A1 (en) 1985-05-01
IE840528L (en) 1984-09-14
AU567332B2 (en) 1987-11-19
CA1218378A (en) 1987-02-24
AU2553784A (en) 1984-09-20
IE57094B1 (en) 1992-04-22
EP0122827A1 (en) 1984-10-24
PH19184A (en) 1986-01-23
PT78238B (en) 1986-04-24
PT78238A (en) 1984-04-01
KR910002945B1 (en) 1991-05-11
GR81821B (en) 1984-12-12
ATE20879T1 (en) 1986-08-15
KR840009078A (en) 1984-12-24
ES530503A0 (en) 1985-05-01

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