DK117225B - Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser. - Google Patents

Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser.

Info

Publication number
DK117225B
DK117225B DK173064AA DK173064A DK117225B DK 117225 B DK117225 B DK 117225B DK 173064A A DK173064A A DK 173064AA DK 173064 A DK173064 A DK 173064A DK 117225 B DK117225 B DK 117225B
Authority
DK
Denmark
Prior art keywords
estrane
androstane
bromoethyl
chloro
mono
Prior art date
Application number
DK173064AA
Other languages
Danish (da)
English (en)
Inventor
K Hoegberg
H Fex
I Koenyves
P Kneip
Original Assignee
Leo Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB14160/63A external-priority patent/GB1016959A/en
Application filed by Leo Ab filed Critical Leo Ab
Publication of DK117225B publication Critical patent/DK117225B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05C19/00—Apparatus specially adapted for applying particulate materials to surfaces
    • B05C19/02—Apparatus specially adapted for applying particulate materials to surfaces using fluidised-bed techniques
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Paints Or Removers (AREA)
  • Glass Compositions (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
DK173064AA 1963-04-09 1964-04-08 Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser. DK117225B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB14160/63A GB1016959A (en) 1963-04-09 1963-04-09 Substituted steroid hormones

Publications (1)

Publication Number Publication Date
DK117225B true DK117225B (da) 1970-03-31

Family

ID=10036092

Family Applications (1)

Application Number Title Priority Date Filing Date
DK173064AA DK117225B (da) 1963-04-09 1964-04-08 Fremgangsmåde til fremstilling af mono- eller di-N-bis-(β-klor- eller bromætyl)-karbamidsyreestere af østran-, androstan- eller pregnanforbindelser.

Country Status (10)

Country Link
US (2) US3299104A (cs)
BE (1) BE646319A (cs)
BR (1) BR6458190D0 (cs)
CH (1) CH452514A (cs)
DK (1) DK117225B (cs)
ES (1) ES298429A1 (cs)
FI (1) FI41742B (cs)
FR (1) FR3331M (cs)
NO (1) NO123943B (cs)
SE (1) SE314977B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499158A (en) * 1964-04-24 1970-03-03 Raytheon Co Circuits utilizing the threshold properties of recombination radiation semiconductor devices
GB1523035A (en) 1976-03-10 1978-08-31 Leo Ab Derivatives of estradiol - 17 - dihydrogen phosphates
EP0105404A1 (en) * 1982-09-30 1984-04-18 Merck & Co. Inc. Derivatives of steroid compounds linked to cyotoxic agents and process for their preparation
SE8802402D0 (sv) * 1988-06-28 1988-06-28 Pharmacia Ab Novel esters
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
JP2554005B2 (ja) * 1993-02-18 1996-11-13 株式会社パーマケム・アジア エストラムスチンフォスフェート又はその塩類の精製方法
US6500669B1 (en) * 1994-05-04 2002-12-31 Massachusetts Institute Of Technology Programmable genotoxic agents and uses therefor
US5882941A (en) * 1994-05-04 1999-03-16 Massachusette Institute Of Technology Programmable genotoxic agents and uses therefor
GB9419153D0 (en) * 1994-09-22 1994-11-09 Erba Carlo Spa Estramustine formulations with improved pharmaceutical properties
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
JP2016519684A (ja) 2013-04-08 2016-07-07 デニス エム ブラウン 準最適に投与された薬物療法の有効性を改善するための及び／又は副作用を低減するための方法および組成物
US9394237B2 (en) 2014-02-03 2016-07-19 Quadriga Biosciences, Inc. β-substituted β-amino acids and analogs as chemotherapeutic agents
CN106132406B (zh) 2014-02-03 2020-03-27 夸德里加生物科学公司 作为化疗剂的β-取代的γ-氨基酸和类似物
KR20180035894A (ko) 2015-08-03 2018-04-06 콰드리가 바이오사이언시스 인코포레이티드 화학치료제로서의 베타-치환된 베타-아미노산 및 유사체 및 이들의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2885413A (en) * 1956-12-17 1959-05-05 Upjohn Co 11-oxygenated estradiol compounds and derivatives
US3081298A (en) * 1959-08-28 1963-03-12 Ciba Geigy Corp New cyclohemiacetals and cyclohemiacetal esters of the pregnane series and a processfor their manufacture

Also Published As

Publication number Publication date
NO123943B (cs) 1972-02-07
ES298429A1 (es) 1964-10-16
FR3331M (fr) 1965-05-24
BE646319A (cs) 1964-07-31
US3299104A (en) 1967-01-17
USRE29199E (en) 1977-05-03
FI41742B (cs) 1969-10-31
BR6458190D0 (pt) 1973-12-26
SE314977B (cs) 1969-09-22
CH452514A (de) 1968-03-15

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