DK1161239T3 - 3- cyclopropylmethoxy-4-difluormethoxy-N-(3,5-dichlorpyrid-4-yl)benzamid til behandling af dissemineret sklerose - Google Patents

3- cyclopropylmethoxy-4-difluormethoxy-N-(3,5-dichlorpyrid-4-yl)benzamid til behandling af dissemineret sklerose

Info

Publication number
DK1161239T3
DK1161239T3 DK00910736T DK00910736T DK1161239T3 DK 1161239 T3 DK1161239 T3 DK 1161239T3 DK 00910736 T DK00910736 T DK 00910736T DK 00910736 T DK00910736 T DK 00910736T DK 1161239 T3 DK1161239 T3 DK 1161239T3
Authority
DK
Denmark
Prior art keywords
dichloropyrid
cyclopropylmethoxy
difluoromethoxy
benzamide
treatment
Prior art date
Application number
DK00910736T
Other languages
Danish (da)
English (en)
Inventor
Hans-Peter Kley
Armin Hatzelmann
Christian Schudt
Karl Sanders
Hermann Amschler
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1161239T3 publication Critical patent/DK1161239T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK00910736T 1999-03-10 2000-03-01 3- cyclopropylmethoxy-4-difluormethoxy-N-(3,5-dichlorpyrid-4-yl)benzamid til behandling af dissemineret sklerose DK1161239T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99104793 1999-03-10
PCT/EP2000/001703 WO2000053182A2 (en) 1999-03-10 2000-03-01 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis
EP00910736A EP1161239B1 (en) 1999-03-10 2000-03-01 3-cyclopropylmethoxy-4-difluoromethoxy-n-(3,5-dichloropyrid-4-yl)benzamide in the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
DK1161239T3 true DK1161239T3 (da) 2005-02-14

Family

ID=8237737

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00910736T DK1161239T3 (da) 1999-03-10 2000-03-01 3- cyclopropylmethoxy-4-difluormethoxy-N-(3,5-dichlorpyrid-4-yl)benzamid til behandling af dissemineret sklerose

Country Status (12)

Country Link
US (1) US6531493B1 (es)
EP (1) EP1161239B1 (es)
JP (1) JP2002538207A (es)
AT (1) ATE279924T1 (es)
AU (1) AU3284000A (es)
CA (1) CA2364258C (es)
DE (1) DE60015098T2 (es)
DK (1) DK1161239T3 (es)
ES (1) ES2231162T3 (es)
PT (1) PT1161239E (es)
SI (1) SI1161239T1 (es)
WO (1) WO2000053182A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1188438A1 (en) * 2000-09-15 2002-03-20 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production
EP1199074A1 (en) * 2000-09-15 2002-04-24 Warner-Lambert Company Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production
WO2002088079A2 (en) * 2001-05-01 2002-11-07 Bristol-Myers Squibb Company Dual inhibitors of pde 7 and pde 4
US20030092706A1 (en) * 2001-11-09 2003-05-15 Johannes Barsig Combination
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ATE485821T1 (de) 2002-05-28 2010-11-15 Nycomed Gmbh Ophthalmologische zubereitung enthaltend roflumilast in der behandlung von krankheiten der augen
US6822114B1 (en) 2002-10-08 2004-11-23 Albemarle Corporation Process for production of fluoroalkoxy-substituted benzamides and their intermediates
PT1606261E (pt) 2003-03-10 2010-01-11 Nycomed Gmbh Novo processo para a preparação de roflumilast
DE102004046235A1 (de) 2004-09-22 2006-03-30 Altana Pharma Ag Arzneimittelzubereitung
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0652868B1 (en) * 1992-07-28 2004-11-10 Aventis Pharma Limited INHIBITORS OF c-AMP PHOSPHODIESTERASE
CN1046939C (zh) 1993-07-02 1999-12-01 比克·古尔顿·劳姆贝尔格化学公司 氟烷氧基取代的苯甲酰胺类及其制备方法和应用
EP0758233B1 (en) * 1994-04-21 2003-12-03 Schering Aktiengesellschaft Pde iv inhibitors for treating multiple sclerosis

Also Published As

Publication number Publication date
ES2231162T3 (es) 2005-05-16
CA2364258C (en) 2008-12-30
SI1161239T1 (en) 2005-06-30
DE60015098D1 (de) 2004-11-25
EP1161239B1 (en) 2004-10-20
AU3284000A (en) 2000-09-28
EP1161239A2 (en) 2001-12-12
US6531493B1 (en) 2003-03-11
DE60015098T2 (de) 2006-02-02
JP2002538207A (ja) 2002-11-12
ATE279924T1 (de) 2004-11-15
WO2000053182A3 (en) 2001-04-12
PT1161239E (pt) 2005-02-28
CA2364258A1 (en) 2000-09-14
WO2000053182A2 (en) 2000-09-14

Similar Documents

Publication Publication Date Title
SE0100901D0 (sv) New composition
DK1200418T3 (da) Nematodicide trifluorbutener
DK1178958T3 (da) N-cyanomethylamider som proteaseinhibitorer
IS6957A (is) Tatrat sölt af 5,8,14,-tríasatetrasýkló[10.3.1.02,11.04,9]-hexadeka-2(11),3,5,7,9,-pentaen og lyfjafræðilegar samsetningar af þeim
DE50202328D1 (de) Amidofunktionelle aminopolydiorganosiloxane
BR0317715A (pt) Composições e processos de uso de collajolie
ID26043A (id) Turunan-turunan 1,3,5-triazina tertrisubstitusi untuk pengobatan infeksi-infeksi hiv
BR0209580A (pt) Derivados de ciclohexan-1, 4 diamina substituìdos
HUP0101439A2 (hu) A II antagonistát tartalmazó nyújtott felszabadulású készítmény, valamint eljárás ennek előállítására és alkalmazása
DK1097173T3 (da) Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler
BR0114903A (pt) 7-azaindóis, sua aplicação como inibidores da fosfodiesterase 4 e processos para a sua preparação
ATE303384T1 (de) 1-biaryl-1,8-naphthyridin-4-one als phosphodieseterase-inhibitoren
IT1320120B1 (it) 2-(3,5-bis-trifluorometil-fenil)-n-metil-n-(6-morfolin-4-il-4-0-tolil-piridin-3-il) -isobutirrammide.
DK1161239T3 (da) 3- cyclopropylmethoxy-4-difluormethoxy-N-(3,5-dichlorpyrid-4-yl)benzamid til behandling af dissemineret sklerose
DK1330458T3 (da) N-(1,2,4-triazoloazinyl)thiophensulfonamidforbindelser som herbicider
DE60112960D1 (de) Kondensierte pyridoindolderivate
SE9801494D0 (sv) Novel use
DK0996435T3 (da) Aminosyrederivater anvendelige til behandling af slagtilfælde
HUP0202592A2 (hu) Lazofoxifen transzdermális adagolása
NO20030868D0 (no) N-(3,5-diklor-2-metoksyfenyl)-4-metoksy-3-piperazin-1-yl- benzensulfonamid
DK1177191T3 (da) Substituerede benzimidazoler, fremstilling og anvendelse deraf som midler til bekæmpelse af parasitiske protozoer
DE60121048D1 (de) PYRAZINOi1'2':1,6öPYRIDOi3,4-BöINDOLDERIVATE
FR2842667B3 (fr) Moto-reducteur notamment pour des betonneuses, des gachoirs et des machines similaires
ATE242763T1 (de) Methoximinophenylessigsäureamide
DK0720597T3 (da) Triarylethylenderivater til terapeutisk anvendelse