DK1158962T3 - Process for preparing solid cyclodextrin-containing dosage forms - Google Patents

Process for preparing solid cyclodextrin-containing dosage forms

Info

Publication number
DK1158962T3
DK1158962T3 DK00916925T DK00916925T DK1158962T3 DK 1158962 T3 DK1158962 T3 DK 1158962T3 DK 00916925 T DK00916925 T DK 00916925T DK 00916925 T DK00916925 T DK 00916925T DK 1158962 T3 DK1158962 T3 DK 1158962T3
Authority
DK
Denmark
Prior art keywords
dosage forms
preparing solid
containing dosage
solid cyclodextrin
cyclodextrin
Prior art date
Application number
DK00916925T
Other languages
Danish (da)
Inventor
Gunther Berndl
Stephan Lehmann
Ulrich Reinhold
Dirk Simon
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Application granted granted Critical
Publication of DK1158962T3 publication Critical patent/DK1158962T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Agronomy & Crop Science (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a method for producing solid dosage forms containing at least one physiologically compatible polymer binding agent, at least one active agent and at least one cyclodextrin as components. According to the method, the components are mixed and plasticised at a temperature below 220 DEG C, without the addition of a solvent. The plastic mixture obtained is shaped into the dosage form. The invention also relates to the dosage forms obtained by said method.
DK00916925T 1999-03-12 2000-03-10 Process for preparing solid cyclodextrin-containing dosage forms DK1158962T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19911097A DE19911097A1 (en) 1999-03-12 1999-03-12 Process for the preparation of solid dosage forms containing cyclodextrin
PCT/EP2000/002142 WO2000054751A1 (en) 1999-03-12 2000-03-10 Method for producing solid dosage forms containing cyclodextrin

Publications (1)

Publication Number Publication Date
DK1158962T3 true DK1158962T3 (en) 2003-01-06

Family

ID=7900771

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00916925T DK1158962T3 (en) 1999-03-12 2000-03-10 Process for preparing solid cyclodextrin-containing dosage forms

Country Status (10)

Country Link
EP (1) EP1158962B1 (en)
JP (1) JP4861552B2 (en)
AT (1) ATE228828T1 (en)
BR (1) BR0008872B1 (en)
CA (1) CA2367020C (en)
DE (2) DE19911097A1 (en)
DK (1) DK1158962T3 (en)
ES (1) ES2187457T3 (en)
PT (1) PT1158962E (en)
WO (1) WO2000054751A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1175205B1 (en) 1999-11-12 2006-06-14 Abbott Laboratories Solid dispersion comprising ritonavir, fenofibrate or griseofulvin
WO2001083520A2 (en) 2000-05-02 2001-11-08 Theravance,Inc Polyacid glycopeptide derivatives
SI1278549T1 (en) 2000-05-02 2009-04-30 Theravance Inc Composition containing a cyclodextrin and a glycopeptide antibiotic
DE10026698A1 (en) 2000-05-30 2001-12-06 Basf Ag Self-emulsifying active ingredient formulation and use of this formulation
WO2001098329A1 (en) 2000-06-22 2001-12-27 Theravance, Inc. Polyhydroxy glycopeptide derivatives
US6872804B2 (en) 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
UA75083C2 (en) 2000-06-22 2006-03-15 Тераванс, Інк. Derivatives of glycopeptidephosphonates
AU2001259303A1 (en) 2000-06-22 2002-01-02 Advanced Medicine, Inc. Glycopeptide carboxy-saccharide derivatives
FR2828380B1 (en) * 2001-08-10 2005-07-29 Fontarome COMPOSITE COMPOSITE COMPOSITION CONTAINING AROMATIC SUBSTANCES AND / OR VOLATILE NON-AROMATIC SUBSTANCES AND / OR SENSITIVE TO EXTERNAL AGENTS, AND PROCESS FOR PRODUCING THE SAME
DE10141682A1 (en) * 2001-08-25 2003-03-06 Beiersdorf Ag Cyclodextrin is used in production of cosmetic and dermatological compositions to give improved filler distribution on the skin
DE10157350A1 (en) * 2001-11-22 2003-05-28 Stockhausen Chem Fab Gmbh Production of controlled release plant treatment composition, comprises kneading water-absorbing polymer containing absorbed water with active agent, e.g. fungicide or insecticide
US7001893B2 (en) * 2002-10-28 2006-02-21 Council Of Scientific And Industrial Research Inclusion complex of Rifampicin, an anti-tubercular drug, with β-cyclodextrin or 2-hydroxypropyl β-cyclodextrin and a process thereof
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US7955630B2 (en) * 2004-09-30 2011-06-07 Kraft Foods Global Brands Llc Thermally stable, high tensile strength encapsulated actives
ES2310948B2 (en) 2005-02-25 2009-09-16 Universidade De Santiago De Compostela PROCEDURE FOR OBTAINING HYDROGELS OF CYCLODEXTRINES WITH GLICIDILETERS, THE COMPOSITIONS OBTAINED AND THEIR APPLICATIONS.
RS62097B1 (en) * 2016-02-04 2021-08-31 Czap Research And Development Llc Controlled-release and stratified cyclodextrin inclusion complex vehicles
DE102016014603A1 (en) 2016-06-30 2018-01-04 Thomas Herkenroth Synthetic ayahuasca
WO2020213010A1 (en) * 2019-04-16 2020-10-22 Celagenex Research (India) Pvt. Ltd. Synergistic lipid controlling compositions
CN113081989B (en) * 2021-03-29 2022-10-21 海南普利制药股份有限公司 Allopurinol sustained release tablet
CN113861347A (en) * 2021-11-02 2021-12-31 南京信息工程大学 Modified cyclodextrin high-molecular slow-release mint-flavor material as well as preparation method and application thereof
CN114588123B (en) * 2022-04-13 2023-12-22 苏州中化药品工业有限公司 High-stability cetirizine hydrochloride tablet and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0624903A (en) * 1992-04-09 1994-02-01 Nippon Bayeragrochem Kk Plant treating agent
DE4446470A1 (en) * 1994-12-23 1996-06-27 Basf Ag Process for the production of dividable tablets
AU725204B2 (en) * 1995-11-23 2000-10-05 Janssen Pharmaceutica N.V. Solid mixtures of cyclodextrins prepared via melt-extrusion

Also Published As

Publication number Publication date
ATE228828T1 (en) 2002-12-15
EP1158962B1 (en) 2002-12-04
DE19911097A1 (en) 2000-09-14
CA2367020C (en) 2008-12-16
PT1158962E (en) 2003-04-30
JP2002539151A (en) 2002-11-19
BR0008872A (en) 2002-01-02
EP1158962A1 (en) 2001-12-05
ES2187457T3 (en) 2003-06-16
BR0008872B1 (en) 2011-05-17
CA2367020A1 (en) 2000-09-21
DE50000866D1 (en) 2003-01-16
WO2000054751A1 (en) 2000-09-21
JP4861552B2 (en) 2012-01-25

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