DK112684A - Substituerede phenylfuranoner med angiogeneseinhiberende virkning - Google Patents

Substituerede phenylfuranoner med angiogeneseinhiberende virkning Download PDF

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Publication number
DK112684A
DK112684A DK112684A DK112684A DK112684A DK 112684 A DK112684 A DK 112684A DK 112684 A DK112684 A DK 112684A DK 112684 A DK112684 A DK 112684A DK 112684 A DK112684 A DK 112684A
Authority
DK
Denmark
Prior art keywords
angiogenese
substituted phenyl
inhibitive effect
phenyl furanones
furanones
Prior art date
Application number
DK112684A
Other languages
Danish (da)
English (en)
Other versions
DK112684D0 (da
Inventor
Gary Allen Koppel
Russell Lavern Barton
Stephen Lyle Briggs
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK112684D0 publication Critical patent/DK112684D0/da
Publication of DK112684A publication Critical patent/DK112684A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
DK112684A 1983-03-14 1984-02-28 Substituerede phenylfuranoner med angiogeneseinhiberende virkning DK112684A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/475,272 US4552895A (en) 1983-03-14 1983-03-14 Furo[3,2-b]furan-2-(3H)-ones

Publications (2)

Publication Number Publication Date
DK112684D0 DK112684D0 (da) 1984-02-28
DK112684A true DK112684A (da) 1984-09-15

Family

ID=23886882

Family Applications (1)

Application Number Title Priority Date Filing Date
DK112684A DK112684A (da) 1983-03-14 1984-02-28 Substituerede phenylfuranoner med angiogeneseinhiberende virkning

Country Status (8)

Country Link
US (1) US4552895A (ko)
EP (1) EP0119795A1 (ko)
JP (1) JPS59176299A (ko)
KR (1) KR860000768B1 (ko)
DK (1) DK112684A (ko)
GB (1) GB2136803B (ko)
GR (1) GR81927B (ko)
HU (1) HUT36125A (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5098933A (en) * 1986-04-29 1992-03-24 Theracel Corporation Pharmaceutically useful Michael addition products of unsaturated aldehydes and ketones and ascorbic acid
JP2779652B2 (ja) * 1988-12-27 1998-07-23 武田薬品工業株式会社 生理活性物質tan―1120,その還元体,それらの製造法および用途ならびに微生物
FR2913422B1 (fr) * 2007-03-09 2009-04-17 Oreal Procede de traitement cosmetique employant des analogues d'ascorbigene, compositions cosmetiques et composes
CN108558797B (zh) * 2018-05-28 2020-04-17 华南师范大学 双醚化呋喃酮含氟衍生物及其制备方法与在制备抗肿瘤药物中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3734929A (en) * 1971-08-27 1973-05-22 Eastman Kodak Co Hexahydro-3,3,6,6-tetramethylfluro-(3,2-b)-furan-2,5-dione and method of its preparation
US4329290A (en) * 1976-07-01 1982-05-11 Sawyer Philip Nicholas Antithrombotic derivatives of ammonium ascorbate
US4208434A (en) * 1978-07-11 1980-06-17 The Coca-Cola Company Color stable food containing anthocyanic pigments and bio-available vitamin C and process for its production
US4231939A (en) * 1979-11-26 1980-11-04 Miles Laboratories, Inc. 2,5-Dioxo-3H,6H-furo[(3,2-b]furan-3a,6a-diacetic acid and salts thereof
DE3111092A1 (de) * 1981-03-20 1982-09-30 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 1.4-3.6-dianhydro-hexitolen
JPS57156479A (en) * 1981-03-24 1982-09-27 Santen Pharmaceut Co Ltd Ascorbic acid derivative
IL67646A0 (en) * 1982-01-15 1983-05-15 Lilly Co Eli Ascorbic acid ethers and related compounds

Also Published As

Publication number Publication date
HUT36125A (en) 1985-08-28
KR840008149A (ko) 1984-12-13
KR860000768B1 (ko) 1986-06-23
GR81927B (ko) 1984-12-12
GB2136803A (en) 1984-09-26
JPS59176299A (ja) 1984-10-05
GB2136803B (en) 1986-09-10
US4552895A (en) 1985-11-12
EP0119795A1 (en) 1984-09-26
DK112684D0 (da) 1984-02-28
GB8406251D0 (en) 1984-04-11

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AHB Application shelved due to non-payment