DK111892B - Fremgangsmåde til fremstilling af pyrazinimidoyl-guanidinforbindelser. - Google Patents

Fremgangsmåde til fremstilling af pyrazinimidoyl-guanidinforbindelser.

Info

Publication number
DK111892B
DK111892B DK313366AA DK313366A DK111892B DK 111892 B DK111892 B DK 111892B DK 313366A A DK313366A A DK 313366AA DK 313366 A DK313366 A DK 313366A DK 111892 B DK111892 B DK 111892B
Authority
DK
Denmark
Prior art keywords
pyrazinimidoyl
preparation
guanidine compounds
guanidine
compounds
Prior art date
Application number
DK313366AA
Other languages
Danish (da)
English (en)
Inventor
E Cragoe
J Jones
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK111892B publication Critical patent/DK111892B/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK313366AA 1965-10-04 1966-06-17 Fremgangsmåde til fremstilling af pyrazinimidoyl-guanidinforbindelser. DK111892B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US492868A US3274192A (en) 1965-10-04 1965-10-04 Derivatives of pyrazine and a method for their preparation

Publications (1)

Publication Number Publication Date
DK111892B true DK111892B (da) 1968-10-21

Family

ID=23957936

Family Applications (1)

Application Number Title Priority Date Filing Date
DK313366AA DK111892B (da) 1965-10-04 1966-06-17 Fremgangsmåde til fremstilling af pyrazinimidoyl-guanidinforbindelser.

Country Status (12)

Country Link
US (1) US3274192A (ja)
BE (1) BE682664A (ja)
BR (1) BR6680520D0 (ja)
CH (1) CH469011A (ja)
DE (1) DE1620010A1 (ja)
DK (1) DK111892B (ja)
ES (1) ES328363A1 (ja)
FR (2) FR1560217A (ja)
GB (1) GB1149638A (ja)
IL (1) IL25802A (ja)
NL (1) NL6608466A (ja)
SE (1) SE329622B (ja)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4402959A (en) * 1980-06-02 1983-09-06 Merck & Co., Inc. Antimicrobial compositions
US4518599A (en) * 1982-09-30 1985-05-21 Merck & Co., Inc. 2-Amino-3-cyano-5-halo-6-(substituted)pyrazine
US4517186A (en) * 1982-09-30 1985-05-14 Merck & Co., Inc. 2-Amino-3,5-dicyano-6-(substituted)pyrazine antimicrobial compounds
US4507299A (en) * 1982-12-27 1985-03-26 Merck & Co., Inc. N-[2-amino-5-halo-6-(substituted)-3-pyrazinyl)-methylene]amine antimicrobial compounds
US4481202A (en) * 1982-12-27 1984-11-06 Merek & Co., Inc. 2-Amino-3-carboxylate-5-halo-6-(substituted)pyrazine antimicrobial compounds
US4442096A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. 2-(Substituted)amino-3-cyano-5-halo-6-(substituted)-pyrazine antimicrobial compounds, compositions and use
US4442095A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. N-[(5-Halo-2,6-(substituted)pyrazinyl)methylene]amine antimicrobial compounds, compositions and use
US4442097A (en) * 1982-12-27 1984-04-10 Merck & Co., Inc. 3-Acyl-2-(substituted) amino-5-halo-6-(substituted) pyrazine antimicrobial compounds, compositions and use
US4512991A (en) * 1982-12-27 1985-04-23 Merck & Co., Inc. 3-Acyl-2-amino-5-halo-6-(substituted)pyrazine antimicrobial compounds
US4479953A (en) * 1983-08-25 1984-10-30 Merck & Co., Inc. Pyrazine aldimine compounds as antimicrobial agents
JP4523093B2 (ja) * 1999-09-20 2010-08-11 広栄化学工業株式会社 ２−アミノ−ブロモピラジン類の製造方法
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
DK2931713T3 (en) 2012-12-17 2017-01-30 Parion Sciences Inc CHLORPYRAZINE CARBOXAMIDE DERIVATIVES USED FOR THE TREATMENT OF DISEASES BENEFITED BY INDEPENDENT MOSPHEREWIN
EP3428153A1 (en) 2012-12-17 2019-01-16 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Also Published As

Publication number Publication date
BR6680520D0 (pt) 1973-12-26
IL25802A (en) 1970-05-21
FR1560217A (ja) 1969-03-21
US3274192A (en) 1966-09-20
BE682664A (ja) 1966-12-16
FR5811M (ja) 1968-02-19
DE1620010A1 (de) 1970-02-12
GB1149638A (en) 1969-04-23
SE329622B (ja) 1970-10-19
ES328363A1 (es) 1967-04-01
NL6608466A (ja) 1967-04-05
CH469011A (de) 1969-02-28

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