DK1112999T3 - Reduktion af azider til aminer ved hjælp af phosphiner - Google Patents

Reduktion af azider til aminer ved hjælp af phosphiner

Info

Publication number
DK1112999T3
DK1112999T3 DK00126169T DK00126169T DK1112999T3 DK 1112999 T3 DK1112999 T3 DK 1112999T3 DK 00126169 T DK00126169 T DK 00126169T DK 00126169 T DK00126169 T DK 00126169T DK 1112999 T3 DK1112999 T3 DK 1112999T3
Authority
DK
Denmark
Prior art keywords
azides
phosphines
amines
reduction
acid derivatives
Prior art date
Application number
DK00126169T
Other languages
Danish (da)
English (en)
Inventor
Hans-Juergen Mair
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1112999T3 publication Critical patent/DK1112999T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK00126169T 1999-12-03 2000-11-30 Reduktion af azider til aminer ved hjælp af phosphiner DK1112999T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99124223 1999-12-03

Publications (1)

Publication Number Publication Date
DK1112999T3 true DK1112999T3 (da) 2003-11-24

Family

ID=8239540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00126169T DK1112999T3 (da) 1999-12-03 2000-11-30 Reduktion af azider til aminer ved hjælp af phosphiner

Country Status (12)

Country Link
US (1) US6462226B1 (fr)
EP (1) EP1112999B1 (fr)
JP (1) JP3502342B2 (fr)
KR (1) KR100405924B1 (fr)
CN (1) CN1225457C (fr)
AT (1) ATE246671T1 (fr)
CA (1) CA2327056C (fr)
DE (1) DE60004316T2 (fr)
DK (1) DK1112999T3 (fr)
ES (1) ES2203392T3 (fr)
JO (1) JO2287B1 (fr)
MX (1) MXPA00011933A (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6518048B2 (en) * 2000-04-10 2003-02-11 Hoffmann-La Roche Inc. Stereo-specific synthesis of shimikic acid derivatives with improved efficiency
EP1791808B1 (fr) * 2004-09-02 2010-07-14 F.Hoffmann-La Roche Ag Procede de preparation d'acide 4,5-diamino shikimique
KR20080085061A (ko) 2005-12-28 2008-09-22 에프. 호프만-라 로슈 아게 타미플루 합성에서의 에폭사이드 중간체
US7977077B2 (en) 2006-01-30 2011-07-12 Board Of Trustees Of Michigan State University Synthesis of intermediates of oseltamivir carboxylates
ES2392207T3 (es) * 2007-09-18 2012-12-05 F. Hoffmann-La Roche Ag Proceso a partir de ácido shikímico para obtener oseltamivir fosfato

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU228450B1 (en) * 1995-02-27 2013-03-28 Gilead Sciences Inc Novel selective inhibitors of viral or bacterial neuraminidases
MXPA99001697A (es) 1996-08-23 2004-04-05 Gilead Sciences Inc Preparacion de derivados de carboxilato de ciclohexeno.
US5859284A (en) * 1996-08-23 1999-01-12 Gilead Sciences, Inc. Preparation of carbocyclic compounds

Also Published As

Publication number Publication date
DE60004316T2 (de) 2004-06-24
CN1298868A (zh) 2001-06-13
JP2001187770A (ja) 2001-07-10
KR20010062068A (ko) 2001-07-07
MXPA00011933A (es) 2002-06-04
CA2327056A1 (fr) 2001-06-03
US6462226B1 (en) 2002-10-08
KR100405924B1 (ko) 2003-11-15
ES2203392T3 (es) 2004-04-16
ATE246671T1 (de) 2003-08-15
EP1112999A3 (fr) 2002-01-30
CN1225457C (zh) 2005-11-02
JP3502342B2 (ja) 2004-03-02
CA2327056C (fr) 2005-09-27
JO2287B1 (en) 2005-09-12
EP1112999A2 (fr) 2001-07-04
DE60004316D1 (de) 2003-09-11
EP1112999B1 (fr) 2003-08-06

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