DK1097173T3 - Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler - Google Patents
Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midlerInfo
- Publication number
- DK1097173T3 DK1097173T3 DK99936898T DK99936898T DK1097173T3 DK 1097173 T3 DK1097173 T3 DK 1097173T3 DK 99936898 T DK99936898 T DK 99936898T DK 99936898 T DK99936898 T DK 99936898T DK 1097173 T3 DK1097173 T3 DK 1097173T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- therapeutic agents
- peptides
- relates
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/246—IL-2
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/116,594 US6168785B1 (en) | 1998-07-16 | 1998-07-16 | Biological applications of new peptides of IL-2 and derivatives and use as therapeutic agents |
| PCT/IB1999/001424 WO2000004048A1 (en) | 1998-07-16 | 1999-07-16 | Peptides of il-2 and derivatives thereof and their use as therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1097173T3 true DK1097173T3 (da) | 2008-09-01 |
Family
ID=22368127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99936898T DK1097173T3 (da) | 1998-07-16 | 1999-07-16 | Anvendelse af peptider af IL-2 og derivater deraf som terapeutiske midler |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US6168785B1 (de) |
| EP (1) | EP1097173B1 (de) |
| AT (1) | ATE396205T1 (de) |
| AU (1) | AU5186799A (de) |
| CA (1) | CA2337511A1 (de) |
| CY (1) | CY1108610T1 (de) |
| DE (1) | DE69938786D1 (de) |
| DK (1) | DK1097173T3 (de) |
| ES (1) | ES2308845T3 (de) |
| PT (1) | PT1097173E (de) |
| WO (1) | WO2000004048A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6929791B2 (en) | 1998-07-16 | 2005-08-16 | Institut Pasteur | Peptides of IL-2 and derivatives thereof |
| US6168785B1 (en) * | 1998-07-16 | 2001-01-02 | Institut Pasteur | Biological applications of new peptides of IL-2 and derivatives and use as therapeutic agents |
| US7488590B2 (en) | 1998-10-23 | 2009-02-10 | Amgen Inc. | Modified peptides as therapeutic agents |
| JP3820105B2 (ja) | 1998-10-23 | 2006-09-13 | キリン−アムジエン・インコーポレーテツド | Ｍｐ１受容体に結合し血小板生成活性を有する二量体トロンボポエチンペプチド模倣体 |
| US7662368B2 (en) * | 1999-07-16 | 2010-02-16 | Institut Pasteur | Method of inducing SHC phosphorylation of inducing the SHC/MAPK pathway by administering a peptide of IL-2 |
| ATE401345T1 (de) * | 2002-08-06 | 2008-08-15 | Aplagen Gmbh | Synthetische mimetika von physiologischen bindungsmolekülen |
| CN1675243A (zh) * | 2002-08-06 | 2005-09-28 | 阿普拉根有限责任公司 | 结合分子 |
| ATE473016T1 (de) | 2003-11-04 | 2010-07-15 | Novartis Vaccines & Diagnostic | Verfahren zur behandlung von krebs mit expression des cd40-antigens |
| US20060024722A1 (en) | 2004-07-30 | 2006-02-02 | Mark Fischer-Colbrie | Samples for detection of oncofetal fibronectin and uses thereof |
| CU23297A1 (es) * | 2004-11-16 | 2008-07-24 | Ct De Inmunologa A Molecular | Formulaciones inmunoterapã0/00uticas para la inducciã"n de autoanticuerpos bloqueadores de la uniã"n de interleucina-2 a su receptor. su uso en el tratamiento del cã ncer |
| ES2732623T3 (es) | 2005-01-06 | 2019-11-25 | Innate Pharma Sa | Tratamientos y métodos de combinación anti-KIR |
| US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
| US9901731B2 (en) * | 2006-01-31 | 2018-02-27 | Medtronic, Inc. | Medical electrical lead having improved inductance |
| US9283260B2 (en) | 2006-04-21 | 2016-03-15 | Amgen Inc. | Lyophilized therapeutic peptibody formulations |
| CU23734A1 (es) | 2009-11-27 | 2011-11-15 | Centro Inmunologia Molecular | Polipéptidos inmunomoduladores derivados de la il-2 con actividad antagonista de esta citocina útiles en la terapia del cáncer y enfermedades infecciosas crónicas |
| CA3144697A1 (en) | 2010-11-12 | 2012-05-18 | Nektar Therapeutics | Conjugates of an il-2 moiety and a polymer |
| WO2015162124A1 (en) * | 2014-04-22 | 2015-10-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the diagnostic of an autoimmune disease |
| US20170157215A1 (en) | 2015-12-04 | 2017-06-08 | Jomoco, Corp. | Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates |
| WO2018215936A1 (en) | 2017-05-24 | 2018-11-29 | Novartis Ag | Antibody-cytokine engrafted proteins and methods of use in the treatment of cancer |
| AU2018372167B2 (en) | 2017-11-21 | 2023-12-07 | The Board Of Trustees Of The Leland Stanford Junior University | Partial agonists of interleukin-2 |
| AU2019274409B2 (en) | 2018-05-21 | 2022-07-14 | Nektar Therapeutics | Selective Treg stimulator RUR20KD-IL-2 and related compositions |
| BR112020025287A2 (pt) | 2018-06-25 | 2021-03-09 | University Of Washington | Projeto de novo de miméticos de interleucina potentes e seletivos |
| JP7303391B2 (ja) | 2020-01-14 | 2023-07-04 | シンセカイン インコーポレイテッド | バイアス型ｉｌ２ムテイン、方法、および組成物 |
| IL313567A (en) | 2021-12-14 | 2024-08-01 | Lilly Co Eli | Dose transmitters for selective TREG stimulator RUR20KD-IL-2 and related preparations |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3377363D1 (en) * | 1982-03-31 | 1988-08-18 | Ajinomoto Kk | Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells |
| US4690915A (en) * | 1985-08-08 | 1987-09-01 | The United States Of America As Represented By The Department Of Health And Human Services | Adoptive immunotherapy as a treatment modality in humans |
| US4879111A (en) * | 1986-04-17 | 1989-11-07 | Cetus Corporation | Treatment of infections with lymphokines |
| JPH03500415A (ja) | 1988-07-05 | 1991-01-31 | アムジエン・インコーポレーテツド | インターロイキン２類似体 |
| NZ234674A (en) * | 1989-08-02 | 1992-02-25 | Seragen Inc | Mutant interleukin-2,dna encoding it, host cells, cytotoxic and toxin-mutant il-2 conjugates |
| CU22222A1 (es) * | 1989-08-03 | 1995-01-31 | Cigb | Procedimiento para la expresion de proteinas heterologicas producidas de forma fusionada en escherichia coli, su uso, vectores de expresion y cepas recombinantes |
| US5336488A (en) * | 1991-08-07 | 1994-08-09 | American Cyanamid Company | Method of treating or preventing mastitis in animals with involuting mammary glands by administering recombinant cytokines |
| US6168785B1 (en) | 1998-07-16 | 2001-01-02 | Institut Pasteur | Biological applications of new peptides of IL-2 and derivatives and use as therapeutic agents |
-
1998
- 1998-07-16 US US09/116,594 patent/US6168785B1/en not_active Expired - Fee Related
-
1999
- 1999-07-16 US US09/720,828 patent/US6825334B1/en not_active Expired - Fee Related
- 1999-07-16 AU AU51867/99A patent/AU5186799A/en not_active Abandoned
- 1999-07-16 CA CA002337511A patent/CA2337511A1/en not_active Abandoned
- 1999-07-16 DK DK99936898T patent/DK1097173T3/da active
- 1999-07-16 EP EP99936898A patent/EP1097173B1/de not_active Expired - Lifetime
- 1999-07-16 AT AT99936898T patent/ATE396205T1/de not_active IP Right Cessation
- 1999-07-16 ES ES99936898T patent/ES2308845T3/es not_active Expired - Lifetime
- 1999-07-16 DE DE69938786T patent/DE69938786D1/de not_active Expired - Lifetime
- 1999-07-16 WO PCT/IB1999/001424 patent/WO2000004048A1/en active IP Right Grant
- 1999-07-16 PT PT99936898T patent/PT1097173E/pt unknown
-
2000
- 2000-09-12 US US09/660,465 patent/US6596853B1/en not_active Expired - Fee Related
-
2003
- 2003-12-05 US US10/727,514 patent/US7101965B2/en not_active Expired - Fee Related
-
2008
- 2008-08-12 CY CY20081100848T patent/CY1108610T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2337511A1 (en) | 2000-01-27 |
| US6168785B1 (en) | 2001-01-02 |
| EP1097173A1 (de) | 2001-05-09 |
| ES2308845T3 (es) | 2008-12-01 |
| CY1108610T1 (el) | 2014-04-09 |
| PT1097173E (pt) | 2008-08-26 |
| AU5186799A (en) | 2000-02-07 |
| DE69938786D1 (de) | 2008-07-03 |
| US20040202661A1 (en) | 2004-10-14 |
| WO2000004048A1 (en) | 2000-01-27 |
| EP1097173B1 (de) | 2008-05-21 |
| US7101965B2 (en) | 2006-09-05 |
| ATE396205T1 (de) | 2008-06-15 |
| US6825334B1 (en) | 2004-11-30 |
| US6596853B1 (en) | 2003-07-22 |
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