DK1089976T3 - Fremgangsmåde til fremstilling af 5-bromisoquinolin og dets 8-nitroderivat - Google Patents
Fremgangsmåde til fremstilling af 5-bromisoquinolin og dets 8-nitroderivatInfo
- Publication number
- DK1089976T3 DK1089976T3 DK99927733T DK99927733T DK1089976T3 DK 1089976 T3 DK1089976 T3 DK 1089976T3 DK 99927733 T DK99927733 T DK 99927733T DK 99927733 T DK99927733 T DK 99927733T DK 1089976 T3 DK1089976 T3 DK 1089976T3
- Authority
- DK
- Denmark
- Prior art keywords
- bromoisoquinoline
- preparing
- derivatives
- nitro derivative
- nitro
- Prior art date
Links
- CYJZJGYYTFQQBY-UHFFFAOYSA-N 5-bromoisoquinoline Chemical compound N1=CC=C2C(Br)=CC=CC2=C1 CYJZJGYYTFQQBY-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- YWWZASFPWWPUBN-UHFFFAOYSA-N 1-bromoisoquinoline Chemical class C1=CC=C2C(Br)=NC=CC2=C1 YWWZASFPWWPUBN-UHFFFAOYSA-N 0.000 abstract 2
- ULGOLOXWHJEZNZ-UHFFFAOYSA-N 5-bromo-8-nitroisoquinoline Chemical class C1=NC=C2C([N+](=O)[O-])=CC=C(Br)C2=C1 ULGOLOXWHJEZNZ-UHFFFAOYSA-N 0.000 abstract 1
- DPRIHFQFWWCIGY-UHFFFAOYSA-N 8-bromoisoquinoline Chemical class C1=NC=C2C(Br)=CC=CC2=C1 DPRIHFQFWWCIGY-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199800884 | 1998-06-22 | ||
| PCT/DK1999/000347 WO1999067218A2 (en) | 1998-06-22 | 1999-06-22 | Method of preparing 5- or 8-bromoisoquinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1089976T3 true DK1089976T3 (da) | 2004-01-19 |
Family
ID=8098619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99927733T DK1089976T3 (da) | 1998-06-22 | 1999-06-22 | Fremgangsmåde til fremstilling af 5-bromisoquinolin og dets 8-nitroderivat |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6500954B1 (enExample) |
| EP (1) | EP1089976B1 (enExample) |
| JP (1) | JP2002518480A (enExample) |
| AT (1) | ATE250584T1 (enExample) |
| AU (1) | AU4498799A (enExample) |
| DE (1) | DE69911603T2 (enExample) |
| DK (1) | DK1089976T3 (enExample) |
| WO (1) | WO1999067218A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040058950A1 (en) * | 2002-07-09 | 2004-03-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions based on anticholinergics and PDE-IV inhibitors |
| BR0312727A (pt) * | 2002-07-17 | 2005-04-19 | Warner Lambert Co | Combinação de um inibidor alostérico da metaloproteinase-13 de matriz com celecoxib ou valdecoxib |
| US20040092522A1 (en) * | 2002-08-15 | 2004-05-13 | Field Mark John | Synergistic combinations |
| US7419981B2 (en) * | 2002-08-15 | 2008-09-02 | Pfizer Inc. | Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor |
| ATE374030T1 (de) * | 2003-07-25 | 2007-10-15 | Hoffmann La Roche | Kombination eines mglur2 antagonists und eines ache inhibitors zur behandlung von akuten und/oder chronischen neurologischen krankheiten |
| WO2005025675A1 (en) * | 2003-09-12 | 2005-03-24 | Pfizer Limited | Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors |
| GB0322140D0 (en) * | 2003-09-22 | 2003-10-22 | Pfizer Ltd | Combinations |
| DE102005061997A1 (de) * | 2005-12-23 | 2007-07-05 | Basf Ag | Naphthalintetracarbonsäurederivate und deren Verwendung |
| CN113264880B (zh) * | 2021-05-25 | 2022-08-30 | 湖北工业大学 | 一种4-卤代异喹啉化合物的制备方法 |
-
1999
- 1999-06-22 DK DK99927733T patent/DK1089976T3/da active
- 1999-06-22 EP EP99927733A patent/EP1089976B1/en not_active Expired - Lifetime
- 1999-06-22 WO PCT/DK1999/000347 patent/WO1999067218A2/en not_active Ceased
- 1999-06-22 JP JP2000555872A patent/JP2002518480A/ja active Pending
- 1999-06-22 DE DE69911603T patent/DE69911603T2/de not_active Expired - Lifetime
- 1999-06-22 AT AT99927733T patent/ATE250584T1/de not_active IP Right Cessation
- 1999-06-22 AU AU44987/99A patent/AU4498799A/en not_active Abandoned
-
2000
- 2000-10-10 US US09/685,025 patent/US6500954B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69911603D1 (de) | 2003-10-30 |
| JP2002518480A (ja) | 2002-06-25 |
| WO1999067218A3 (en) | 2000-03-16 |
| US6500954B1 (en) | 2002-12-31 |
| DE69911603T2 (de) | 2004-07-29 |
| EP1089976B1 (en) | 2003-09-24 |
| AU4498799A (en) | 2000-01-10 |
| ATE250584T1 (de) | 2003-10-15 |
| WO1999067218A2 (en) | 1999-12-29 |
| EP1089976A1 (en) | 2001-04-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0835257T3 (da) | Mellemprodukter og fremgangsmåde til fremstilling af camptothecin-derivater (CPT-11) og beslægtede forbindelser | |
| HU9601857D0 (en) | New benzyl-piperidine- or -tetrahydro-pyridine derivatives and processes for producing them | |
| TR200103273T2 (tr) | Hemisentetik yöntem ve yeni bileşimler. | |
| DE69516866D1 (de) | Stereochemische wortmanninderivate | |
| DK1007092T3 (da) | En fremgangsmåde til inhibering af komplementaktivering via det alternative forlöb | |
| NO20062092L (no) | Nye fremgangsmater for fremstilling av N-desmetylzopiklon og optisk rent (+)-N-desmetylzopiklon og optisk rent (-)-N-desmetylzopiklon | |
| HUP9700126A3 (en) | 2-oxo- and 2-thio-1,2-dihydroquinolinyl-oxazotidinone derivatives and pharmaceutical compositions containing them, process for producing the compounds and intermediates of them | |
| DE59606920D1 (de) | Chirale methylphenyloxazolidinone | |
| EA200001129A3 (ru) | Способ получения 4-карбоксиамино-2-замещенного-1,2,3,4-тетрагидрохинолина | |
| DK0863887T3 (da) | Mellemprodukter til hemisyntese af taxaner og fremgangsmåder til deres fremstilling | |
| DK1089976T3 (da) | Fremgangsmåde til fremstilling af 5-bromisoquinolin og dets 8-nitroderivat | |
| NO995531D0 (no) | Nye mellomprodukter og fremgangsmåte for fremstilling derav | |
| NO20023150L (no) | Fremgangsmate for fremstilling av citalopram | |
| DK1140933T3 (da) | Fremgangsmåde til fremstilling af N6-substituerede deaza-adenosinderivater | |
| NO991633D0 (no) | FremgangsmÕte ved biotransformasjon av kolkisinforbindelser til de tilsvarende 3-glykosyl-derivater | |
| DK0937062T3 (da) | Nye cis-3,4-chroman-derivater, der er nyttige i forebyggelsen eller behandlingen af østrogen-relaterede sygdomme eller syndromer | |
| ATE196292T1 (de) | Zwischenprodukte um 2-imidazolin-5onederivate herzustellen. | |
| DK0937057T3 (da) | Hidtil ukendte (-)-enantiomerer af cis-3,4-chromanderivater anvendelige i forebyggelse eller behandling af østrogenrelaterede sygdomme eller syndromer | |
| YU1500A (sh) | Postupak za dobijanje aminskih derivata alkiloksifuranona, dobijena jedinjenja i korišćenje ovih jedinjenja | |
| DK0693055T3 (da) | Hidtil ukendt fremgangsmåde til fremstilling af clonidinderivater | |
| PL356064A1 (en) | Method for preparing 2-(2-arylmorpholin-2-yl)ethanol derivatives and intermediates | |
| NO20020218D0 (no) | Fremgangsmåte for fremstilling av mykner | |
| DK0830356T3 (da) | Fremgangsmåde til syntese af benzo[b]thiophener | |
| BG104964A (bg) | Подобрен метод за получаване на фармацевтично ценни норбензоморфанови производни | |
| NO984227L (no) | Cycloalkylderivater og syntese i fast fase av slike derivater |