DK1089761T3 - Medicines containing bisphosphonic acids and their derivatives for the prophylaxis and treatment of autoimmune diseases and allergies - Google Patents
Medicines containing bisphosphonic acids and their derivatives for the prophylaxis and treatment of autoimmune diseases and allergiesInfo
- Publication number
- DK1089761T3 DK1089761T3 DK99941383T DK99941383T DK1089761T3 DK 1089761 T3 DK1089761 T3 DK 1089761T3 DK 99941383 T DK99941383 T DK 99941383T DK 99941383 T DK99941383 T DK 99941383T DK 1089761 T3 DK1089761 T3 DK 1089761T3
- Authority
- DK
- Denmark
- Prior art keywords
- acid
- derivatives
- bisphosphonic
- autoimmune diseases
- bisphosphonic acids
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
The invention relates to the use of bisphosphonic acids and the derivatives thereof for producing medicaments for preventing and treating autoimmune diseases or allergies combined with the autoantigens specifically used for treating the respective autoimmune disease or combined with the allergens specifically used for treating the respective allergy. Some examples of the bisphosphonic acids or derivatives thereof which are used according to the invention include amino-hydroxy-methylidene-bisphosphonic acid (AMP), 2-amino-1-hydroxyethylidene-1,1-bisphosphonic acid (AEP), pamidronic acid, alendronic acid, 6-amino-1-hydroxyhexylidene-1,1-bisphosphonic acid (AHP), amidinomethylene-bisphosphonic acid (AIMP), ibandronic acid, risedronic acid, zoledronic acid, cimadronic acid, and tiludronic acid. Some examples of autoimmune diseases in which bisphosphonic acids or the derivatives thereof can be used include rheumatoid arthritis, severe myasthenia, diabetes mellitus, uveitis, and scleroderma. The bisphosphonic acids or the derivatives thereof and the autoantigens or allergens can be applied simultaneously or in succession. The preparations of the combinations can be used in solid form, as ointments, as solutions or as sprays.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19828450A DE19828450A1 (en) | 1998-06-26 | 1998-06-26 | Use of bisphosphonic acid compounds and autoantigens or allergens |
| PCT/DE1999/001844 WO2000000182A2 (en) | 1998-06-26 | 1999-06-24 | Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1089761T3 true DK1089761T3 (en) | 2003-02-03 |
Family
ID=7872064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99941383T DK1089761T3 (en) | 1998-06-26 | 1999-06-24 | Medicines containing bisphosphonic acids and their derivatives for the prophylaxis and treatment of autoimmune diseases and allergies |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1089761B1 (en) |
| JP (1) | JP2002519319A (en) |
| KR (1) | KR20010053211A (en) |
| AT (1) | ATE224734T1 (en) |
| AU (1) | AU740605B2 (en) |
| CA (1) | CA2334711C (en) |
| DE (2) | DE19828450A1 (en) |
| DK (1) | DK1089761T3 (en) |
| EA (1) | EA200100080A1 (en) |
| EE (1) | EE200000756A (en) |
| ES (1) | ES2184496T3 (en) |
| HR (1) | HRP20000820A2 (en) |
| HU (1) | HUP0102873A3 (en) |
| ID (1) | ID27515A (en) |
| IL (1) | IL139966A0 (en) |
| IS (1) | IS5748A (en) |
| MX (1) | MXPA00012338A (en) |
| NO (1) | NO20006572L (en) |
| NZ (1) | NZ509505A (en) |
| PL (1) | PL345287A1 (en) |
| PT (1) | PT1089761E (en) |
| SK (1) | SK19602000A3 (en) |
| TR (1) | TR200003821T2 (en) |
| WO (1) | WO2000000182A2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL349438A1 (en) | 1998-12-23 | 2002-07-29 | Jomaa Pharmaka Gmbh | Use of bisphosphonates for the prevention and treatment of infectious processes |
| CN1217666C (en) * | 1998-12-25 | 2005-09-07 | 东丽株式会社 | Interleukin-6 production inhibitors |
| JP2004528365A (en) * | 2001-05-02 | 2004-09-16 | ノバルティス アクチエンゲゼルシャフト | Inhaled bisphosphonate administration method for treatment or prevention of bone resorption and osteoporosis |
| ES2315411T3 (en) | 2001-07-20 | 2009-04-01 | Bioagency Ag | ORGANOFOSPHORATED COMPOUNDS FOR THE ACTIVATION OF T GAMMA / DELTA CELLS. |
| GB0307989D0 (en) * | 2003-04-07 | 2003-05-14 | Mcewen Lab Ltd | Therapeutic composition |
| EP1713489B1 (en) * | 2004-08-23 | 2011-01-19 | Teva Pharmaceutical Industries Ltd | Crystalline form of ibandronate sodium and processes for preparation thereof |
| WO2007032808A1 (en) * | 2005-09-12 | 2007-03-22 | Dr. Reddy's Laboratories Ltd. | Crystalline trihydrate of zoledronic acid |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993005052A1 (en) * | 1991-09-05 | 1993-03-18 | Toray Industries, Inc. | Methanediphosphonic acid derivative, production thereof and medicinal use thereof |
| ATE219945T1 (en) * | 1995-01-23 | 2002-07-15 | Xenotech Inc | COMPOSITION FOR PREVENTING OSTEOLYSIS AND METASTASES |
-
1998
- 1998-06-26 DE DE19828450A patent/DE19828450A1/en not_active Withdrawn
-
1999
- 1999-06-24 EE EEP200000756A patent/EE200000756A/en unknown
- 1999-06-24 SK SK1960-2000A patent/SK19602000A3/en unknown
- 1999-06-24 KR KR1020007014813A patent/KR20010053211A/en not_active Application Discontinuation
- 1999-06-24 TR TR2000/03821T patent/TR200003821T2/en unknown
- 1999-06-24 NZ NZ509505A patent/NZ509505A/en not_active IP Right Cessation
- 1999-06-24 ES ES99941383T patent/ES2184496T3/en not_active Expired - Lifetime
- 1999-06-24 MX MXPA00012338A patent/MXPA00012338A/en unknown
- 1999-06-24 ID IDW20002676A patent/ID27515A/en unknown
- 1999-06-24 IL IL13996699A patent/IL139966A0/en unknown
- 1999-06-24 JP JP2000556767A patent/JP2002519319A/en active Pending
- 1999-06-24 DK DK99941383T patent/DK1089761T3/en active
- 1999-06-24 CA CA002334711A patent/CA2334711C/en not_active Expired - Fee Related
- 1999-06-24 PT PT99941383T patent/PT1089761E/en unknown
- 1999-06-24 DE DE59902856T patent/DE59902856D1/en not_active Expired - Lifetime
- 1999-06-24 PL PL99345287A patent/PL345287A1/en unknown
- 1999-06-24 HU HU0102873A patent/HUP0102873A3/en unknown
- 1999-06-24 AT AT99941383T patent/ATE224734T1/en active
- 1999-06-24 EA EA200100080A patent/EA200100080A1/en unknown
- 1999-06-24 AU AU55033/99A patent/AU740605B2/en not_active Ceased
- 1999-06-24 WO PCT/DE1999/001844 patent/WO2000000182A2/en not_active Application Discontinuation
- 1999-06-24 EP EP99941383A patent/EP1089761B1/en not_active Expired - Lifetime
-
2000
- 2000-11-29 HR HR20000820A patent/HRP20000820A2/en not_active Application Discontinuation
- 2000-12-01 IS IS5748A patent/IS5748A/en unknown
- 2000-12-21 NO NO20006572A patent/NO20006572L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ509505A (en) | 2002-11-26 |
| NO20006572L (en) | 2001-02-21 |
| IL139966A0 (en) | 2002-02-10 |
| EA200100080A1 (en) | 2001-06-25 |
| ATE224734T1 (en) | 2002-10-15 |
| WO2000000182A2 (en) | 2000-01-06 |
| ES2184496T3 (en) | 2003-04-01 |
| DE19828450A1 (en) | 1999-12-30 |
| CA2334711C (en) | 2006-12-05 |
| SK19602000A3 (en) | 2001-07-10 |
| JP2002519319A (en) | 2002-07-02 |
| IS5748A (en) | 2000-12-01 |
| KR20010053211A (en) | 2001-06-25 |
| HUP0102873A3 (en) | 2002-04-29 |
| EP1089761B1 (en) | 2002-09-25 |
| AU5503399A (en) | 2000-01-17 |
| AU740605B2 (en) | 2001-11-08 |
| HRP20000820A2 (en) | 2001-12-31 |
| TR200003821T2 (en) | 2001-06-21 |
| PL345287A1 (en) | 2001-12-03 |
| EE200000756A (en) | 2002-04-15 |
| CA2334711A1 (en) | 2000-01-06 |
| WO2000000182A3 (en) | 2000-03-30 |
| ID27515A (en) | 2001-04-12 |
| DE59902856D1 (en) | 2002-10-31 |
| HUP0102873A2 (en) | 2001-12-28 |
| EP1089761A2 (en) | 2001-04-11 |
| MXPA00012338A (en) | 2003-04-25 |
| NO20006572D0 (en) | 2000-12-21 |
| PT1089761E (en) | 2003-02-28 |
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