DK106191D0 - Mellemprodukter til fremstilling af penemer og carbapenemer - Google Patents

Mellemprodukter til fremstilling af penemer og carbapenemer

Info

Publication number
DK106191D0
DK106191D0 DK911061A DK106191A DK106191D0 DK 106191 D0 DK106191 D0 DK 106191D0 DK 911061 A DK911061 A DK 911061A DK 106191 A DK106191 A DK 106191A DK 106191 D0 DK106191 D0 DK 106191D0
Authority
DK
Denmark
Prior art keywords
peneme
carbapeneme
intermediates
manufacturing
carbapeneme manufacturing
Prior art date
Application number
DK911061A
Other languages
English (en)
Other versions
DK106191A (da
Inventor
Michael P Kirkup
Stuart W Mc Combie
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK106191D0 publication Critical patent/DK106191D0/da
Publication of DK106191A publication Critical patent/DK106191A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
DK106191A 1988-12-05 1991-06-04 Mellemprodukter til fremstilling af penemer og carbapenemer DK106191A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/279,751 US4876365A (en) 1988-12-05 1988-12-05 Intermediate compounds for preparing penems and carbapenems
PCT/US1989/005341 WO1990006316A1 (en) 1988-12-05 1989-12-01 Intermediate compounds for preparing penems and carbapenems

Publications (2)

Publication Number Publication Date
DK106191D0 true DK106191D0 (da) 1991-06-04
DK106191A DK106191A (da) 1991-07-03

Family

ID=23070295

Family Applications (1)

Application Number Title Priority Date Filing Date
DK106191A DK106191A (da) 1988-12-05 1991-06-04 Mellemprodukter til fremstilling af penemer og carbapenemer

Country Status (9)

Country Link
US (1) US4876365A (da)
EP (2) EP0373448A1 (da)
JP (1) JPH04500077A (da)
AU (1) AU4809790A (da)
CA (1) CA2004355A1 (da)
DK (1) DK106191A (da)
IL (1) IL92522A0 (da)
WO (1) WO1990006316A1 (da)
ZA (1) ZA899208B (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems
US5342631A (en) * 1992-12-29 1994-08-30 Wm. Wrigley Jr. Company Wax-free chewing gum including special oligosaccharide binders
HUT73237A (en) * 1993-07-09 1996-07-29 Schering Corp New process for the synthesis of azetidinones
US5631365A (en) 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US6593078B1 (en) 1999-04-16 2003-07-15 Schering Corporation Use of azetidinone compounds
US6584357B1 (en) * 2000-10-17 2003-06-24 Sony Corporation Method and system for forming an acoustic signal from neural timing difference data
US6982251B2 (en) * 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
CN100509058C (zh) * 2001-01-26 2009-07-08 先灵公司 过氧化物酶体增殖物激活受体(ppar)活化剂和甾醇吸收抑制剂的组合药以及对于血管适应症的治疗
SK9502003A3 (en) * 2001-01-26 2003-12-02 Schering Corp Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
EP1353695A2 (en) * 2001-01-26 2003-10-22 Schering Corporation Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
DE60221798T2 (de) * 2001-01-26 2008-06-05 Schering Corp. Kombinationen von gallensäure sequestriermitteln und hemmern der sterol absorption zur behandlung von kardiovaskulären indikationen
AR032643A1 (es) * 2001-01-26 2003-11-19 Schering Corp Combinaciones de inhibidor(es) de absorcion de esterol con agente(s) cardiovascular(es) para el tratamiento de condiciones vasculares
US7071181B2 (en) * 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
US7417039B2 (en) * 2001-01-26 2008-08-26 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
NZ527852A (en) 2001-03-28 2005-03-24 Schering Corp Enantioselective synthesis of azetidinone intermediate compounds
ES2275007T3 (es) * 2001-05-25 2007-06-01 Schering Corporation Uso de derivados de azetidinona sustitudos en el tratamiento de la enfermedad de alzeimer.
HUP0401501A3 (en) * 2001-09-21 2012-02-28 Schering Corp Treating or preventing vascular inflammation using pharmaceutical compositions containing sterol absorption inhibitor(s)
US20030119808A1 (en) * 2001-09-21 2003-06-26 Schering Corporation Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) * 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
ES2272776T3 (es) * 2001-09-21 2007-05-01 Schering Corporation Tratamiento de xantomas con derivados de azetidinona como inhibidores de la absorcion de esterol.
US20030204096A1 (en) * 2002-03-25 2003-10-30 Schering Corporation Enantioselective synthesis of azetidinone intermediate compounds
US7560449B2 (en) * 2002-11-06 2009-07-14 Schering Corporation Methods and therapeutic combinations for the treatment of demyelination
MXPA05009503A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
CA2517573C (en) 2003-03-07 2011-12-06 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
MXPA05009501A (es) 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CA2544309A1 (en) * 2003-11-05 2005-05-26 Schering Corporation Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301074A (en) * 1977-11-17 1981-11-17 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
IL59081A0 (en) * 1979-01-10 1980-05-30 Schering Corp 2-penem compounds and a method for preparing them
US4378314A (en) * 1979-09-21 1983-03-29 Bristol Myers Company Antibacterial agents and metal containing azetidinone intermediates therefore
ATE10838T1 (de) * 1980-02-28 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. 4-substituierte 2-oxoazetidin-verbindungen, verfahren zu deren herstellung und ihre verwendung zur antibiotika-herstellung.
DE3167198D1 (en) * 1980-08-16 1984-12-20 Beecham Group Plc Process for the preparation of 2-thio penem derivatives and intermediates therefor
CA1190236A (en) * 1981-10-23 1985-07-09 Edward J.J. Grabowski Antibiotic synthesis
US4388310A (en) * 1982-03-01 1983-06-14 Merck & Co., Inc. 6-Amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids
US4530793A (en) * 1982-11-29 1985-07-23 Schering Corporation Processes for the production of penems
US4675317A (en) * 1983-01-25 1987-06-23 Merck & Co., Inc. 2-unsaturated alkylthio-pen-2-em-3-carboxylic acids
EP0126709B1 (de) * 1983-03-28 1991-04-03 Ciba-Geigy Ag Verfahren zur Herstellung von optisch aktiven Azetidinonen
US4504485A (en) * 1983-04-04 1985-03-12 Schering Corporation 5R,6S,8R-6-(1-Hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylic acid
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF
GB8321004D0 (en) * 1983-08-04 1983-09-07 Erba Farmitalia Azetidinones
US4584133A (en) * 1983-11-07 1986-04-22 Schering Corporation Process for the production of penems
US4596677A (en) * 1984-04-06 1986-06-24 Bristol-Myers Company Anhydropenicillin intermediates
GB8416652D0 (en) * 1984-06-29 1984-08-01 Erba Farmitalia Penem derivatives
US4663451A (en) * 1985-05-09 1987-05-05 Farmitalia Carlo Erba S.P.A. Process for the synthesis of penems and penams
ATE93520T1 (de) * 1984-10-01 1993-09-15 Ciba Geigy Ag Verfahren zur herstellung von optisch aktiven acyloxyazetidinonen.
US4740595A (en) * 1986-03-13 1988-04-26 Schering Corporation Preparation of azetidinones via N-protected oxirancecarboxamide intermediates
GB8702139D0 (en) * 1987-01-30 1987-03-04 Ici Plc Process
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems

Also Published As

Publication number Publication date
US4876365A (en) 1989-10-24
DK106191A (da) 1991-07-03
ZA899208B (en) 1990-09-26
CA2004355A1 (en) 1990-06-05
WO1990006316A1 (en) 1990-06-14
IL92522A0 (en) 1990-08-31
AU4809790A (en) 1990-06-26
JPH04500077A (ja) 1992-01-09
EP0373448A1 (en) 1990-06-20
EP0447456A1 (en) 1991-09-25

Similar Documents

Publication Publication Date Title
DK106191D0 (da) Mellemprodukter til fremstilling af penemer og carbapenemer
DK40085A (da) Indretning og fremgangsmaade til bekaempelse af skadedyr
BR8901942A (pt) Relogio
DK302187A (da) Indretning til fastholdelse af et kateter og fremgangsmaade til fremstilling af samme indretning
DK674288A (da) Fremgangsmaade til fremstilling af mikrokapsler
DK107586A (da) Transducer og fremgangsmaade til fremstilling af en saadan
DK400088D0 (da) Fremstilling og anvendelse af t-cellesuppressorfaktor
DK0625586T3 (da) Konstruktionselement og fremgangsmåde til fremstilling af dette
DK154523C (da) Laasering og anvendelse af laaseringen
NO172472C (no) For og fremgangsmaate til fremstilling derav
DK349689D0 (da) Fremgangsmaade til fremstilling af keramiske formdele
DK241790D0 (da) Fremgangsmaade til fremstilling af sucralfat og aai-10001
DK24985D0 (da) Tandstikker og fremgangsmaade til fremstilling af samme
DK313787A (da) Muffesamling og fremgangsmaade til fremstilling af samme
DK490785D0 (da) Suturnaal og fremgangsmaade til fremstilling af denne
DK352489A (da) Fremgangsmaade og mellemprodukter til fremstilling af isofluran
DK80889D0 (da) Badeanlaeg og fremgangsmaade til anvendelse af samme
DK75290D0 (da) Stoebt boerste og fremgangsmaade til fremstilling af samme
DK54590A (da) Fremgangsmaade til modifikation og reduktion af kulaske
DK0497774T3 (da) Fremgangsmåde og arrangement til køling af en bygning
DK178289A (da) Fremgangsmaade til fremstilling af gamma-pyroner
NO179337C (no) Bygningselement
DK156737C (da) Fremgangsmaade til opbygning og demontering af konstruktionsdele
DK178991D0 (da) Fremgangsmaade til fremstilling af flexotrykforme
DK448388D0 (da) Kateter og fremgangsmaade til fremstilling af samme