DK1024822T3 - CD8 som inhibitor for det cellulære immunsystem - Google Patents

CD8 som inhibitor for det cellulære immunsystem

Info

Publication number
DK1024822T3
DK1024822T3 DK98950218T DK98950218T DK1024822T3 DK 1024822 T3 DK1024822 T3 DK 1024822T3 DK 98950218 T DK98950218 T DK 98950218T DK 98950218 T DK98950218 T DK 98950218T DK 1024822 T3 DK1024822 T3 DK 1024822T3
Authority
DK
Denmark
Prior art keywords
inhibitor
immune system
cellular immune
ctl
activity
Prior art date
Application number
DK98950218T
Other languages
English (en)
Inventor
Bent Karsten John Rad Jakobsen
Andrew Kelvin John Radc Sewell
George Fu Gao
Ulrich Conrad Hypo Verei Gerth
Original Assignee
Avidex Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avidex Ltd filed Critical Avidex Ltd
Application granted granted Critical
Publication of DK1024822T3 publication Critical patent/DK1024822T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70517—CD8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DK98950218T 1997-10-28 1998-10-28 CD8 som inhibitor for det cellulære immunsystem DK1024822T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9722779.7A GB9722779D0 (en) 1997-10-28 1997-10-28 Human CD8 as an inhibitor of the cellular immune system
PCT/GB1998/003235 WO1999021576A1 (en) 1997-10-28 1998-10-28 Cd8 as an inhibitor of the cellular immune system

Publications (1)

Publication Number Publication Date
DK1024822T3 true DK1024822T3 (da) 2002-08-05

Family

ID=10821228

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98950218T DK1024822T3 (da) 1997-10-28 1998-10-28 CD8 som inhibitor for det cellulære immunsystem

Country Status (17)

Country Link
US (1) US20070191278A1 (da)
EP (1) EP1024822B1 (da)
JP (1) JP2001521005A (da)
KR (1) KR100585246B1 (da)
CN (1) CN1256147C (da)
AT (1) ATE215833T1 (da)
AU (1) AU752910B2 (da)
CA (1) CA2308463A1 (da)
DE (1) DE69804839T2 (da)
DK (1) DK1024822T3 (da)
ES (1) ES2175798T3 (da)
GB (1) GB9722779D0 (da)
HK (1) HK1031099A1 (da)
NO (1) NO20002148L (da)
NZ (1) NZ504240A (da)
PT (1) PT1024822E (da)
WO (1) WO1999021576A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9929993D0 (en) * 1999-12-17 2000-02-09 Avidex Ltd Substances
GB0107628D0 (en) * 2001-03-27 2001-05-16 Avidex Ltd Substances
GB0114533D0 (en) 2001-06-14 2001-08-08 Avidex Ltd Substances
GB0115071D0 (en) * 2001-06-20 2001-08-15 Avidex Ltd Substances
US20050084967A1 (en) 2002-06-28 2005-04-21 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
GB2398300A (en) * 2003-02-17 2004-08-18 Isis Innovation Method and compositions for boosting immune response
EP1778296B1 (en) * 2004-07-20 2012-06-06 Isogenis, Inc. Specific inhibition of autoimmunity and diseases associated with autoantigens
GB0510627D0 (en) 2005-05-25 2005-06-29 Avidex Ltd Polypeptides
US8871515B2 (en) 2008-09-17 2014-10-28 Isogenis, Inc. Construction of fully-deleted adenovirus-based gene delivery vectors and uses thereof
SG10201510092QA (en) * 2010-12-09 2016-01-28 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
WO2016149404A1 (en) 2015-03-16 2016-09-22 California Institute Of Technology Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making
CN115109120A (zh) * 2016-04-04 2022-09-27 英蒂分子公司 Cd8-特异性捕获剂、组合物及使用和制备方法
EP3519425B1 (en) 2016-09-29 2024-02-28 Indi Molecular, Inc. Compositions for detection, inhibition and imaging of indoleamine 2,3-dioxygenase 1 (ido1) and methods of making and using same
EP3638687A1 (en) 2017-06-15 2020-04-22 Indi Molecular, Inc. Il-17f and il-17a-specific capture agents, compositions, and methods of using and making
WO2022098743A1 (en) 2020-11-03 2022-05-12 Indi Molecular, Inc. Compositions, imaging, and therapeutic methods targeting folate receptor 1 (folr1)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2050346A1 (en) * 1989-03-15 1990-09-16 Mark L. Tykocinski Cd8-based pharmaceuticals
US5601828A (en) * 1989-03-15 1997-02-11 Tkb Associates Limited Partnership CD8 derivatives and methods of use for cellular modulation and enhancement of cellular engraftment
US5242687A (en) * 1989-03-15 1993-09-07 Tkb Associates Limited Partnership Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells
US5645837A (en) * 1995-01-17 1997-07-08 Thomas Jefferson University Peptides that inhibit T cell activation and methods of using the same

Also Published As

Publication number Publication date
ATE215833T1 (de) 2002-04-15
CN1256147C (zh) 2006-05-17
EP1024822B1 (en) 2002-04-10
WO1999021576A1 (en) 1999-05-06
KR20010024570A (ko) 2001-03-26
CN1283120A (zh) 2001-02-07
JP2001521005A (ja) 2001-11-06
ES2175798T3 (es) 2002-11-16
DE69804839D1 (de) 2002-05-16
US20070191278A1 (en) 2007-08-16
NO20002148L (no) 2000-06-27
DE69804839T2 (de) 2002-10-10
AU752910B2 (en) 2002-10-03
AU9637498A (en) 1999-05-17
HK1031099A1 (en) 2001-06-01
NZ504240A (en) 2002-11-26
CA2308463A1 (en) 1999-05-06
EP1024822A1 (en) 2000-08-09
KR100585246B1 (ko) 2006-06-01
GB9722779D0 (en) 1997-12-24
PT1024822E (pt) 2002-09-30
NO20002148D0 (no) 2000-04-27

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