DK1001956T3 - 2,3-Benzodiazepinderivater - Google Patents
2,3-BenzodiazepinderivaterInfo
- Publication number
- DK1001956T3 DK1001956T3 DK98936578T DK98936578T DK1001956T3 DK 1001956 T3 DK1001956 T3 DK 1001956T3 DK 98936578 T DK98936578 T DK 98936578T DK 98936578 T DK98936578 T DK 98936578T DK 1001956 T3 DK1001956 T3 DK 1001956T3
- Authority
- DK
- Denmark
- Prior art keywords
- benzodiazepine derivatives
- benzodiazepines
- epilepsy
- stereoisomers
- variables
- Prior art date
Links
- RPBDCDQMCRHNLM-UHFFFAOYSA-N C1=NNC=C2C=CC=CC2=C1 Chemical class C1=NNC=C2C=CC=CC2=C1 RPBDCDQMCRHNLM-UHFFFAOYSA-N 0.000 title abstract 2
- 208000007101 Muscle Cramp Diseases 0.000 abstract 1
- 208000005392 Spasm Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9701325A HUP9701325A1 (hu) | 1997-07-31 | 1997-07-31 | Új 2,3-benzodiazepin-származékok |
| PCT/HU1998/000071 WO1999006408A1 (en) | 1997-07-31 | 1998-07-27 | New 2,3-benzodiazepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1001956T3 true DK1001956T3 (da) | 2003-08-18 |
Family
ID=89995445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98936578T DK1001956T3 (da) | 1997-07-31 | 1998-07-27 | 2,3-Benzodiazepinderivater |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6482819B1 (ko) |
| EP (1) | EP1001956B1 (ko) |
| JP (1) | JP2001512124A (ko) |
| KR (2) | KR100521959B1 (ko) |
| AT (1) | ATE239729T1 (ko) |
| AU (1) | AU741162B2 (ko) |
| CA (1) | CA2296586C (ko) |
| DE (1) | DE69814401T2 (ko) |
| DK (1) | DK1001956T3 (ko) |
| ES (1) | ES2202879T3 (ko) |
| HU (1) | HUP9701325A1 (ko) |
| PT (1) | PT1001956E (ko) |
| WO (1) | WO1999006408A1 (ko) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10041671C1 (de) * | 2000-08-10 | 2002-06-13 | Schering Ag | Verfahren zur Herstellung von Imidazo[1,2-c][2,3]benzodiazepinen sowie Phenylessigsäureester und Oxazol-Derivate als Zwischenprodukte bei deren Herstellung |
| EP2338492A1 (en) * | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
| CN112321401B (zh) * | 2020-11-10 | 2023-04-28 | 西安石油大学 | 一种催化氧化异色满制备2-羟乙基苯基酮的方法 |
| EP4403185A1 (en) | 2021-09-15 | 2024-07-24 | University of The Ryukyus | Pharmaceutical composition for treating cognitive decline or for treating overweightness or obesity |
| WO2023042887A1 (ja) | 2021-09-15 | 2023-03-23 | 国立大学法人 琉球大学 | 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU219778B (hu) | 1990-12-21 | 2001-07-30 | Gyógyszerkutató Intézet Közös Vállalat | Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények |
| DE4428835A1 (de) | 1994-08-01 | 1996-02-08 | Schering Ag | Neue 3-substituierte 3H-2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel |
| CA2198751C (en) * | 1994-08-31 | 2006-07-11 | Benjamin Alan Anderson | Dihydro-2,3-benzodiazepine derivatives |
| DE19604919A1 (de) | 1996-02-01 | 1997-08-07 | Schering Ag | Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel |
-
1997
- 1997-07-31 HU HU9701325A patent/HUP9701325A1/hu unknown
-
1998
- 1998-07-27 DK DK98936578T patent/DK1001956T3/da active
- 1998-07-27 PT PT98936578T patent/PT1001956E/pt unknown
- 1998-07-27 ES ES98936578T patent/ES2202879T3/es not_active Expired - Lifetime
- 1998-07-27 CA CA002296586A patent/CA2296586C/en not_active Expired - Fee Related
- 1998-07-27 AU AU85540/98A patent/AU741162B2/en not_active Ceased
- 1998-07-27 US US09/463,440 patent/US6482819B1/en not_active Expired - Fee Related
- 1998-07-27 KR KR10-2000-7000873A patent/KR100521959B1/ko not_active IP Right Cessation
- 1998-07-27 WO PCT/HU1998/000071 patent/WO1999006408A1/en active IP Right Grant
- 1998-07-27 DE DE69814401T patent/DE69814401T2/de not_active Expired - Fee Related
- 1998-07-27 JP JP2000505166A patent/JP2001512124A/ja not_active Ceased
- 1998-07-27 AT AT98936578T patent/ATE239729T1/de not_active IP Right Cessation
- 1998-07-27 EP EP98936578A patent/EP1001956B1/en not_active Expired - Lifetime
- 1998-07-28 KR KR1020007000864A patent/KR20010022287A/ko active Search and Examination
Also Published As
| Publication number | Publication date |
|---|---|
| US6482819B1 (en) | 2002-11-19 |
| HUP9701325A1 (hu) | 2000-08-28 |
| HU9701325D0 (en) | 1997-09-29 |
| ES2202879T3 (es) | 2004-04-01 |
| AU741162B2 (en) | 2001-11-22 |
| KR20010022294A (ko) | 2001-03-15 |
| EP1001956B1 (en) | 2003-05-07 |
| WO1999006408A1 (en) | 1999-02-11 |
| EP1001956A1 (en) | 2000-05-24 |
| DE69814401T2 (de) | 2004-02-26 |
| CA2296586A1 (en) | 1999-02-11 |
| KR20010022287A (ko) | 2001-03-15 |
| ATE239729T1 (de) | 2003-05-15 |
| PT1001956E (pt) | 2003-09-30 |
| CA2296586C (en) | 2007-04-03 |
| JP2001512124A (ja) | 2001-08-21 |
| AU8554098A (en) | 1999-02-22 |
| DE69814401D1 (de) | 2003-06-12 |
| KR100521959B1 (ko) | 2005-10-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY117896A (en) | Quinazoline derivatives | |
| GEP20022676B (en) | 4-Phenyl-Pyridine Derivatives, Method for Their Production and Their Use for Treatment of Disorders Caused by Antagonist of NK-1 Receptors | |
| BR9709959A (pt) | Derivados tricìclicos de fenilamino substituìdo para o tratamento de doenças hiperproliferativas | |
| TR200003478T2 (tr) | Antikanser maddeleri olarak faydalı izotiyazol türevleri | |
| UA66825C2 (uk) | Азаполіциклічні сполуки, конденсовані з арилом, фармацевтична композиція, спосіб лікування та спосіб зниження нікотинової залежності | |
| BR9901491A (pt) | 7-hetero-biciclo [2.2.1] - heptanos. | |
| MY133392A (en) | Novel substituted pyrazole derivatives | |
| UA72881C2 (uk) | Похідні тієнопіридину, фармацевтична композиція з використанням таких сполук (варіанти), проміжна сполука | |
| BR0108610A (pt) | Compostos azapolicìclicos condensados com arila | |
| MY133473A (en) | Haterocyclic glycyl beta-alanine derivatives. | |
| WO2001010846A3 (en) | 1,4-diazepine derivatives for the treatment of diseases related to the central nervous system | |
| DK1056704T3 (da) | Antitumormidler | |
| BG104983A (en) | Aryl fused azapolycyclic compounds | |
| BG103687A (en) | Atropisomers of 3-heteroaryl-4(3h)-quinazolinones for the treatment of neurodegenerative processes and conditions related to the central nervous system | |
| ES2191099T3 (es) | Derivados de hidantoina como productos intermedios para principios activos farmaceuticos. | |
| MX9708416A (es) | Derivados de piperazino como antagonistas de neuroquininas. | |
| ATE239729T1 (de) | 2,3-benzodiazepin-derivate | |
| MY133169A (en) | Substituted heterocyclic benzocycloalkenes and the use thereof as substances having an analgesic effect | |
| ATE261724T1 (de) | Antikonvulsive derivate zur behandlung von posttraumatischen stresserkrankungen | |
| DE69822937D1 (de) | Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen | |
| GEP19991780B (en) | Use of Pyrrolidine Derivatives for Treating Alcoholism | |
| BG105549A (en) | Use of n-substituted azabicycloalkane derivatives for treating diseases of the central nervous system | |
| DE69614508D1 (de) | Thiol derivate mit metallopeptidase inhibierender aktivitat | |
| BG105247A (en) | N-substituted azabicycloheptane derivatives, production and use thereof | |
| BR0008791A (pt) | Derivados anticonvulsivos, úteis no tratamento de tremor essencial |