DK1000034T3 - Substituerede 6-alkylphenanthridiner - Google Patents
Substituerede 6-alkylphenanthridinerInfo
- Publication number
- DK1000034T3 DK1000034T3 DK98942571T DK98942571T DK1000034T3 DK 1000034 T3 DK1000034 T3 DK 1000034T3 DK 98942571 T DK98942571 T DK 98942571T DK 98942571 T DK98942571 T DK 98942571T DK 1000034 T3 DK1000034 T3 DK 1000034T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkylphenanthridines
- substituted
- ipharmaceutically
- compositions
- compounds
- Prior art date
Links
- 229940099471 Phosphodiesterase inhibitor Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002571 phosphodiesterase inhibitor Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97112794 | 1997-07-25 | ||
| PCT/EP1998/004476 WO1999005112A1 (en) | 1997-07-25 | 1998-07-18 | Substituted 6-alkylphenanthridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1000034T3 true DK1000034T3 (da) | 2003-01-27 |
Family
ID=8227118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98942571T DK1000034T3 (da) | 1997-07-25 | 1998-07-18 | Substituerede 6-alkylphenanthridiner |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6214839B1 (enExample) |
| EP (1) | EP1000034B1 (enExample) |
| JP (1) | JP2001510826A (enExample) |
| AT (1) | ATE224372T1 (enExample) |
| AU (1) | AU9066498A (enExample) |
| DE (1) | DE69808099T2 (enExample) |
| DK (1) | DK1000034T3 (enExample) |
| ES (1) | ES2184318T3 (enExample) |
| PT (1) | PT1000034E (enExample) |
| SI (1) | SI1000034T1 (enExample) |
| WO (1) | WO1999005112A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20020158B1 (en) | 1999-08-21 | 2007-08-31 | Altana Pharma Ag | Action of synergistic combination |
| ES2236288T3 (es) * | 2000-07-14 | 2005-07-16 | Altana Pharma Ag | 6-heteroarilfenantridinas. |
| AU2001281965A1 (en) * | 2000-07-14 | 2002-01-30 | Byk Gulden Lomberg Chemische Fabrik G.M.B.H. | Novel 6-phenylphenanthridines |
| WO2004019945A1 (en) * | 2002-08-29 | 2004-03-11 | Altana Pharma Ag | 3-hydroxy-6-phenylphenanthridines as pde-4 inhibitors |
| EP1539164B1 (en) | 2002-08-29 | 2006-12-20 | ALTANA Pharma AG | 2-hydroxy-6-phenylphenanthridines as pde-4 inhibitors |
| EP1624893A2 (en) | 2003-04-01 | 2006-02-15 | Applied Research Systems ARS Holding N.V. | Inhibitors of phosphodiesterases in infertility |
| WO2005077906A1 (en) | 2004-02-18 | 2005-08-25 | Altana Pharma Ag | Novel guanidinyl-substituted hydroxy-6-phenylphenenthridines as effective phosphodiesterase (pde) 4 inhibitors |
| AU2005219576B2 (en) | 2004-03-03 | 2011-06-30 | Takeda Gmbh | Novel hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors |
| AR049419A1 (es) * | 2004-03-03 | 2006-08-02 | Altana Pharma Ag | Hidroxi-6-fenilfenantridinas sustituidas con heterociclilo |
| CN1926113B (zh) * | 2004-03-10 | 2010-06-23 | 尼科梅德有限责任公司 | 新的酰氨基取代的羟基-6-苯基菲啶化合物及其作为pde4抑制剂的应用 |
| EP1791496B1 (en) | 2004-08-31 | 2019-07-31 | C.R. Bard, Inc. | Self-sealing ptfe graft with kink resistance |
| NZ589278A (en) | 2005-03-02 | 2012-04-27 | Nycomed Gmbh | Selected salts of 6-heterocyclyl substituted hexahydrophenanthridine derivatives |
| CA2611119A1 (en) * | 2005-06-08 | 2006-12-14 | C.R. Bard Inc. | Grafts and stents having inorganic bio-compatible calcium salt |
| US8066758B2 (en) | 2005-06-17 | 2011-11-29 | C. R. Bard, Inc. | Vascular graft with kink resistance after clamping |
| EP1945138A4 (en) | 2005-11-09 | 2010-02-10 | Bard Inc C R | IMPLANTS AND STENT PROSTHESES |
| US9198749B2 (en) | 2006-10-12 | 2015-12-01 | C. R. Bard, Inc. | Vascular grafts with multiple channels and methods for making |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1199773B (de) * | 1962-02-23 | 1965-09-02 | Hoffmann La Roche | Verfahren zur Herstellung von 6-Methyl-8, 9-methylendioxy-1, 2, 3, 4, 4a, 5, 6, 10b-octahydrophenanthridin und dessen Salzen |
| US3243438A (en) | 1962-02-23 | 1966-03-29 | Hoffmann La Roche | Octahydro phenanthridine compounds |
| US4309545A (en) * | 1980-07-28 | 1982-01-05 | Pfizer Inc. | Oximino-1-hydroxyoctahydrobenzo[c]quinolines and derivatives thereof |
-
1998
- 1998-07-18 PT PT98942571T patent/PT1000034E/pt unknown
- 1998-07-18 ES ES98942571T patent/ES2184318T3/es not_active Expired - Lifetime
- 1998-07-18 US US09/462,507 patent/US6214839B1/en not_active Expired - Fee Related
- 1998-07-18 DK DK98942571T patent/DK1000034T3/da active
- 1998-07-18 SI SI9830300T patent/SI1000034T1/xx unknown
- 1998-07-18 EP EP98942571A patent/EP1000034B1/en not_active Expired - Lifetime
- 1998-07-18 WO PCT/EP1998/004476 patent/WO1999005112A1/en not_active Ceased
- 1998-07-18 AU AU90664/98A patent/AU9066498A/en not_active Abandoned
- 1998-07-18 JP JP2000504111A patent/JP2001510826A/ja not_active Withdrawn
- 1998-07-18 DE DE69808099T patent/DE69808099T2/de not_active Expired - Fee Related
- 1998-07-18 AT AT98942571T patent/ATE224372T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU9066498A (en) | 1999-02-16 |
| DE69808099T2 (de) | 2003-05-15 |
| DE69808099D1 (de) | 2002-10-24 |
| ATE224372T1 (de) | 2002-10-15 |
| JP2001510826A (ja) | 2001-08-07 |
| ES2184318T3 (es) | 2003-04-01 |
| SI1000034T1 (en) | 2003-04-30 |
| US6214839B1 (en) | 2001-04-10 |
| WO1999005112A1 (en) | 1999-02-04 |
| EP1000034B1 (en) | 2002-09-18 |
| EP1000034A1 (en) | 2000-05-17 |
| PT1000034E (pt) | 2003-02-28 |
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