DK0991428T3 - Delta-1,2-bicyklo-[4,4,0]-funktionelle farvestoffer til kontrastforstærkning ved optisk billeddannelse - Google Patents
Delta-1,2-bicyklo-[4,4,0]-funktionelle farvestoffer til kontrastforstærkning ved optisk billeddannelseInfo
- Publication number
- DK0991428T3 DK0991428T3 DK97925619T DK97925619T DK0991428T3 DK 0991428 T3 DK0991428 T3 DK 0991428T3 DK 97925619 T DK97925619 T DK 97925619T DK 97925619 T DK97925619 T DK 97925619T DK 0991428 T3 DK0991428 T3 DK 0991428T3
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- alkoxyalkyl
- hydroxyalkyl
- group
- different
- Prior art date
Links
- 239000000975 dye Substances 0.000 title abstract 2
- 238000012634 optical imaging Methods 0.000 title 1
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 5
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 4
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 4
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000005358 mercaptoalkyl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000027 (C1-C10) alkoxy group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 abstract 1
- 125000003396 thiol group Chemical class [H]S* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/645,310 US5672332A (en) | 1996-05-13 | 1996-05-13 | Delta 1,2 bicyclo 4,4,0! functional dyes for contrast enhancement in optical imaging |
| PCT/US1997/008385 WO1997042978A1 (en) | 1996-05-13 | 1997-05-09 | Δ1,2bicyclo[4,4,0] functional dyes for contrast enhancement in optical imaging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0991428T3 true DK0991428T3 (da) | 2003-11-17 |
Family
ID=24588511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97925619T DK0991428T3 (da) | 1996-05-13 | 1997-05-09 | Delta-1,2-bicyklo-[4,4,0]-funktionelle farvestoffer til kontrastforstærkning ved optisk billeddannelse |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5672332A (da) |
| EP (1) | EP0991428B1 (da) |
| JP (1) | JP2001521488A (da) |
| AT (1) | ATE246007T1 (da) |
| CA (1) | CA2253951C (da) |
| DE (1) | DE69723880T2 (da) |
| DK (1) | DK0991428T3 (da) |
| ES (1) | ES2202622T3 (da) |
| PT (1) | PT991428E (da) |
| WO (1) | WO1997042978A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030180221A1 (en) * | 1998-09-18 | 2003-09-25 | Schering Ag | Near infrared fluorescent contrast agent and fluorescence imaging |
| US7547721B1 (en) | 1998-09-18 | 2009-06-16 | Bayer Schering Pharma Ag | Near infrared fluorescent contrast agent and fluorescence imaging |
| JP2000095758A (ja) | 1998-09-18 | 2000-04-04 | Schering Ag | 近赤外蛍光造影剤および蛍光造影方法 |
| US20070092450A1 (en) * | 2000-10-16 | 2007-04-26 | Mallinckrodt Inc. | Tissue-specific exogenous optical agents |
| US20040180809A1 (en) * | 2000-10-16 | 2004-09-16 | Mallinckrodt Inc. | Tissue-specific exogenous optical agents |
| US6761878B2 (en) * | 2001-10-17 | 2004-07-13 | Mallinckrodt, Inc. | Pathological tissue detection and treatment employing targeted benzoindole optical agents |
| AU2002360766A1 (en) * | 2001-12-21 | 2003-07-30 | Threshold Pharmaceuticals, Inc. | Methods for cancer imaging |
| US20030152577A1 (en) * | 2002-02-07 | 2003-08-14 | Mallinckrodt Inc. | Dye-bioconjugates for simultaneous optical diagnostic and therapeutic applications |
| EP2393420B1 (en) * | 2009-02-06 | 2018-05-30 | Beth Israel Deaconess Medical Center, Inc. | Charge-balanced imaging agents |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4973572A (en) * | 1987-12-21 | 1990-11-27 | Eastman Kodak Company | Infrared absorbing cyanine dyes for dye-donor element used in laser-induced thermal dye transfer |
| US5108882A (en) * | 1989-09-26 | 1992-04-28 | Eastman Kodak Company | Infrared-sensitive photographic element containing at least two photosensitive layers |
| US5013642A (en) * | 1989-11-15 | 1991-05-07 | Eastman Kodak Company | Photographic element |
| US5346801A (en) * | 1992-04-01 | 1994-09-13 | Konica Corporation | Method of forming images |
| DE69503116T2 (de) * | 1994-02-28 | 1999-02-18 | Imation Corp (N.D.Ges.D. Staates Delaware), Oakdale, Minn. | Sensibilisatoren für photothermographische elemente |
| US5541054B1 (en) * | 1995-04-20 | 1998-11-17 | Imation Corp | Spectral sensitizing dyes for photothermographic elements |
-
1996
- 1996-05-13 US US08/645,310 patent/US5672332A/en not_active Expired - Lifetime
-
1997
- 1997-05-09 DE DE69723880T patent/DE69723880T2/de not_active Expired - Lifetime
- 1997-05-09 AT AT97925619T patent/ATE246007T1/de not_active IP Right Cessation
- 1997-05-09 WO PCT/US1997/008385 patent/WO1997042978A1/en active IP Right Grant
- 1997-05-09 EP EP97925619A patent/EP0991428B1/en not_active Expired - Lifetime
- 1997-05-09 PT PT97925619T patent/PT991428E/pt unknown
- 1997-05-09 DK DK97925619T patent/DK0991428T3/da active
- 1997-05-09 ES ES97925619T patent/ES2202622T3/es not_active Expired - Lifetime
- 1997-05-09 CA CA002253951A patent/CA2253951C/en not_active Expired - Fee Related
- 1997-05-09 JP JP54115597A patent/JP2001521488A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DE69723880T2 (de) | 2004-05-27 |
| EP0991428A4 (en) | 2000-04-12 |
| PT991428E (pt) | 2003-12-31 |
| JP2001521488A (ja) | 2001-11-06 |
| CA2253951A1 (en) | 1997-11-20 |
| WO1997042978A1 (en) | 1997-11-20 |
| EP0991428B1 (en) | 2003-07-30 |
| EP0991428A1 (en) | 2000-04-12 |
| US5672332A (en) | 1997-09-30 |
| DE69723880D1 (de) | 2003-09-04 |
| ES2202622T3 (es) | 2004-04-01 |
| CA2253951C (en) | 2003-04-22 |
| ATE246007T1 (de) | 2003-08-15 |
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