DK0957921T3 - 17alpha-dihydroequilenin til forebyggelse af kognitiv dysfunktion - Google Patents
17alpha-dihydroequilenin til forebyggelse af kognitiv dysfunktionInfo
- Publication number
- DK0957921T3 DK0957921T3 DK97946571T DK97946571T DK0957921T3 DK 0957921 T3 DK0957921 T3 DK 0957921T3 DK 97946571 T DK97946571 T DK 97946571T DK 97946571 T DK97946571 T DK 97946571T DK 0957921 T3 DK0957921 T3 DK 0957921T3
- Authority
- DK
- Denmark
- Prior art keywords
- dihydroequilenin
- cognitive dysfunction
- 17alpha
- prevention
- alzheimer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/753,988 US5719137A (en) | 1996-12-03 | 1996-12-03 | Method of preventing neurodegeneration and cognitive dysfunction using 17α-dihydroequilenin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0957921T3 true DK0957921T3 (da) | 2006-12-11 |
Family
ID=25033016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97946571T DK0957921T3 (da) | 1996-12-03 | 1997-11-11 | 17alpha-dihydroequilenin til forebyggelse af kognitiv dysfunktion |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5719137A (da) |
| EP (1) | EP0957921B1 (da) |
| JP (1) | JP2001505574A (da) |
| AT (1) | ATE340578T1 (da) |
| AU (1) | AU5171898A (da) |
| CA (1) | CA2272891A1 (da) |
| DE (1) | DE69736746T2 (da) |
| DK (1) | DK0957921T3 (da) |
| ES (1) | ES2277361T3 (da) |
| WO (1) | WO1998024448A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6271221B1 (en) | 1996-12-10 | 2001-08-07 | American Home Products Corporation | Use of equilenin as an antioxidant |
| US5994337A (en) * | 1997-01-13 | 1999-11-30 | Wake Forest University | Effects of 17α-dihydroequilenin on plasma lipid and lipoprotein, glucose, insulin concentrations, coronary artery vasomotor function, and reproductive organ and mammary gland proliferation in atherosclerotic mammals |
| WO1998043647A1 (en) | 1997-03-28 | 1998-10-08 | Massachusetts Institute Of Technology, Inc. | Regulation of amyloid precursor protein (app) expression by estrogenic compounds |
| WO1999055894A1 (en) | 1998-04-29 | 1999-11-04 | Oklahoma Medical Research Foundation | Construction of retroviral producer cells from adenoviral and retroviral vectors |
| US20060040904A1 (en) * | 2004-08-17 | 2006-02-23 | Ahmed Salah U | Vaginal cream compositions, kits thereof and methods of using thereof |
| WO2006084082A1 (en) * | 2005-02-03 | 2006-08-10 | Duramed Pharmaceuticals, Inc. | Compositions of unconjugated estrogens and methods for their use |
| EP2289487A1 (en) * | 2005-12-27 | 2011-03-02 | Teva Women's Health, Inc. | Conjugated estrogen compositions, applicators, kits, and methods of making and use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3507889A (en) * | 1968-06-11 | 1970-04-21 | American Home Prod | Process for the preparation of 17alpha-dihydroequilenin and related compounds |
| US4154820A (en) * | 1976-02-23 | 1979-05-15 | Akzona Incorporated | Compositions containing alkali metal sulfate salts of conjugated estrogens and antioxidants as stabilizers |
| US4379780A (en) * | 1980-09-29 | 1983-04-12 | American Home Products Corporation | 17 α-Dihydroequilin hapten and assay method |
| IL107343A (en) * | 1992-11-02 | 2003-10-31 | Wyeth Corp | PHARMACEUTICAL COMPOSITION FOR LOWERING BLOOD LIPID LEVEL, COMPRISING, 17alpha-DIHYDROEQUILENIN |
| US5545635A (en) * | 1995-05-23 | 1996-08-13 | Eli Lilly And Company | Inhibiting bone loss with equilenin |
-
1996
- 1996-12-03 US US08/753,988 patent/US5719137A/en not_active Expired - Fee Related
-
1997
- 1997-11-11 EP EP97946571A patent/EP0957921B1/en not_active Expired - Lifetime
- 1997-11-11 CA CA002272891A patent/CA2272891A1/en not_active Withdrawn
- 1997-11-11 WO PCT/US1997/020279 patent/WO1998024448A1/en active IP Right Grant
- 1997-11-11 DE DE69736746T patent/DE69736746T2/de not_active Expired - Fee Related
- 1997-11-11 ES ES97946571T patent/ES2277361T3/es not_active Expired - Lifetime
- 1997-11-11 AT AT97946571T patent/ATE340578T1/de not_active IP Right Cessation
- 1997-11-11 JP JP52558498A patent/JP2001505574A/ja not_active Ceased
- 1997-11-11 AU AU51718/98A patent/AU5171898A/en not_active Abandoned
- 1997-11-11 DK DK97946571T patent/DK0957921T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0957921A1 (en) | 1999-11-24 |
| AU5171898A (en) | 1998-06-29 |
| EP0957921B1 (en) | 2006-09-27 |
| WO1998024448A1 (en) | 1998-06-11 |
| US5719137A (en) | 1998-02-17 |
| EP0957921A4 (en) | 2002-10-02 |
| JP2001505574A (ja) | 2001-04-24 |
| DE69736746D1 (de) | 2006-11-09 |
| CA2272891A1 (en) | 1998-06-11 |
| ES2277361T3 (es) | 2007-07-01 |
| ATE340578T1 (de) | 2006-10-15 |
| DE69736746T2 (de) | 2007-08-16 |
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