DK0920413T3 - Kompleksdannende reagens til boronforbindelser og tilsvarende komplekser - Google Patents

Kompleksdannende reagens til boronforbindelser og tilsvarende komplekser

Info

Publication number
DK0920413T3
DK0920413T3 DK97934313T DK97934313T DK0920413T3 DK 0920413 T3 DK0920413 T3 DK 0920413T3 DK 97934313 T DK97934313 T DK 97934313T DK 97934313 T DK97934313 T DK 97934313T DK 0920413 T3 DK0920413 T3 DK 0920413T3
Authority
DK
Denmark
Prior art keywords
general formula
reagents
complex
boron compound
complexes
Prior art date
Application number
DK97934313T
Other languages
English (en)
Inventor
Mark L Stolowitz
Robert J Kaiser
Kevin P Lund
Steven M Torkelson
Original Assignee
Prolinx Inc
Systemix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/689,341 external-priority patent/US5847192A/en
Priority claimed from US08/691,929 external-priority patent/US5744627A/en
Application filed by Prolinx Inc, Systemix Inc filed Critical Prolinx Inc
Application granted granted Critical
Publication of DK0920413T3 publication Critical patent/DK0920413T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • C07D207/444Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
    • C07D207/448Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide
    • C07D207/452Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide with hydrocarbon radicals, substituted by hetero atoms, directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/51Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/10Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • C07D213/71Sulfur atoms to which a second hetero atom is attached
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02Boron compounds
    • C07F5/025Boronic and borinic acid compounds
DK97934313T 1996-08-05 1997-07-24 Kompleksdannende reagens til boronforbindelser og tilsvarende komplekser DK0920413T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/689,341 US5847192A (en) 1994-01-28 1996-08-05 Boronic compound complexing reagents and complexes
US08/691,929 US5744627A (en) 1994-01-28 1996-08-05 Boronic compound complexing reagents and complexes
PCT/US1997/013143 WO1998005629A1 (en) 1996-08-05 1997-07-24 Boronic compound complexing reagents and complexes

Publications (1)

Publication Number Publication Date
DK0920413T3 true DK0920413T3 (da) 2003-03-03

Family

ID=27104393

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97934313T DK0920413T3 (da) 1996-08-05 1997-07-24 Kompleksdannende reagens til boronforbindelser og tilsvarende komplekser

Country Status (11)

Country Link
EP (1) EP0920413B1 (da)
JP (1) JP4270522B2 (da)
AT (1) ATE227704T1 (da)
AU (1) AU727144B2 (da)
CA (1) CA2262451C (da)
DE (1) DE69717117T2 (da)
DK (1) DK0920413T3 (da)
ES (1) ES2187800T3 (da)
PT (1) PT920413E (da)
RU (1) RU99104137A (da)
WO (1) WO1998005629A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133409A (en) * 1996-12-19 2000-10-17 Aventis Pharmaceuticals Products Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
US6392010B1 (en) 1996-12-19 2002-05-21 Aventis Pharmaceuticals Inc. Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
AU7730500A (en) * 1999-09-30 2001-04-30 Nanogen, Inc. Biomolecular attachment sites on microelectronic arrays and methods thereof
US6960298B2 (en) 2001-12-10 2005-11-01 Nanogen, Inc. Mesoporous permeation layers for use on active electronic matrix devices
US8747870B2 (en) 2006-04-20 2014-06-10 University Of Utah Research Foundation Polymeric compositions and methods of making and using thereof
EP2012803A4 (en) * 2006-04-20 2012-08-01 Univ Utah Res Found POLYMER COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF
US10154804B2 (en) 2007-01-31 2018-12-18 Medtronic Minimed, Inc. Model predictive method and system for controlling and supervising insulin infusion
CN104892457B (zh) * 2011-07-25 2017-07-28 中国医学科学院医药生物技术研究所 一种异羟肟酸类衍生物、其药物组合物、制备方法及用途
EP2897070A1 (en) 2012-08-30 2015-07-22 Medtronic MiniMed, Inc. Safeguarding techniques for a closed-loop insulin infusion system
US9526834B2 (en) 2012-08-30 2016-12-27 Medtronic Minimed, Inc. Safeguarding measures for a closed-loop insulin infusion system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK98996A3 (en) * 1994-01-28 1997-02-05 Prolinx Inc Bioconjugate complexes

Also Published As

Publication number Publication date
AU727144B2 (en) 2000-12-07
EP0920413B1 (en) 2002-11-13
CA2262451A1 (en) 1998-02-12
DE69717117D1 (de) 2002-12-19
JP2001507333A (ja) 2001-06-05
WO1998005629A1 (en) 1998-02-12
RU99104137A (ru) 2001-01-20
DE69717117T2 (de) 2003-07-17
AU3740297A (en) 1998-02-25
CA2262451C (en) 2006-10-24
JP4270522B2 (ja) 2009-06-03
ATE227704T1 (de) 2002-11-15
EP0920413A1 (en) 1999-06-09
ES2187800T3 (es) 2003-06-16
PT920413E (pt) 2003-03-31

Similar Documents

Publication Publication Date Title
DE69126816T2 (de) Metallkomplexe, die Addukte von Säure und Dioximliganden enthalten, zur Markierung von Proteinen und anderen Amin enthaltenden Verbindungen
DE60012485D1 (de) Salicylamid-lanthanid komplexe zur verwendung als lumineszenzmarker
ATE285394T1 (de) Phthalamid-lanthanid komplexe zur verwendung als lumineszenzmarker
BG103856A (en) The application of single-dimensional nuclear magnetic resonance for ligand identification with biomolecular targets
DK0920413T3 (da) Kompleksdannende reagens til boronforbindelser og tilsvarende komplekser
NO972155L (no) Fremgangsmåte og opplösning for dannelse av et konversjonsbelegg på en metalloverflate
CY1105381T1 (el) Αλατα βορονικου οξεως
IT8619236A0 (it) Chelati di ioni metallici paramagnetici.
IT8026043A0 (it) Sistema substrato di amplificazione della luminescenza chimica perimmuno-chimica.
DK0915832T3 (da) Kompleksdannende reagenser til boronforbindelser og højstabile komplekser
DK0741734T3 (da) Phenylborsyrekomplekser
DK1047669T3 (da) Perfluor-N-alkylsulfonsyrederivater
EP0247848A3 (en) Water-compatible reducible compounds and their use in analytical compositions and methods
ATE189225T1 (de) Cyclische verbindungen des dreiwertigen phosphors
Suzuki et al. Determination of manganese in biological materials by atomic absorption spectroscopy
ATE250065T1 (de) Verfahren zur demethoxycarbonylisierung von porphirinicverbindungen, wie pheophorbiderivate
AU1494401A (en) Methods for creating a compound library and identifying lead chemical templates and ligands for target molecules
WO2001029555A3 (de) Monofluorierte polycyclische aromatische verbindungen und ihre verwendung als begleitsubstanzen polycyclischer aromatischer verbindungen
DE3882674T2 (de) Verfahren zur bindung von biologischen reagenzien an poroese traeger.
Zoroddu et al. Interactions of tetrakis-(μ-trifluoroacetamidato)-dirhodium (II) with 2, 4-diaminopyrimidines
AU6771981A (en) Chemical luminescence amplification substrate system for immuno chemistry
RO112628B1 (ro) Procedeu de obţinere a soluţiei giemsa-reactiv analitic special
刘伟生 et al. Complexes of Rare Earth Picrates with 1, 10-Phenanthroline-N-Oxide
Ting The Preparation and Application of Dilithium Tetracarbonyl Iron (II)
ATE89284T1 (de) Aminoanthracendion-bis-platinkomplexe, nuetzlich als antitumor-agenzien.