DK0850217T3 - Fremgangsmåde til fremstilling af arylalkynyl-N-hydroxy-carbamid-derivater med lipoxygenaseinhibitor-aktivitet - Google Patents
Fremgangsmåde til fremstilling af arylalkynyl-N-hydroxy-carbamid-derivater med lipoxygenaseinhibitor-aktivitetInfo
- Publication number
- DK0850217T3 DK0850217T3 DK96931435T DK96931435T DK0850217T3 DK 0850217 T3 DK0850217 T3 DK 0850217T3 DK 96931435 T DK96931435 T DK 96931435T DK 96931435 T DK96931435 T DK 96931435T DK 0850217 T3 DK0850217 T3 DK 0850217T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- arylalkynyl
- hydroxy
- inhibitor activity
- lipoxygenase inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
- C07C43/29—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
- C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
- C07C273/1827—X being H
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
- C07C43/295—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US357895P | 1995-09-12 | 1995-09-12 | |
| PCT/US1996/013892 WO1997010206A1 (en) | 1995-09-12 | 1996-08-27 | Process for the preparation of arylalkynyl-n-hydroxyurea derivatives having lipoxygenase inhibitory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0850217T3 true DK0850217T3 (da) | 2000-09-11 |
Family
ID=21706542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96931435T DK0850217T3 (da) | 1995-09-12 | 1996-08-27 | Fremgangsmåde til fremstilling af arylalkynyl-N-hydroxy-carbamid-derivater med lipoxygenaseinhibitor-aktivitet |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5714633A (da) |
| EP (1) | EP0850217B1 (da) |
| JP (1) | JP4400933B2 (da) |
| AT (1) | ATE191466T1 (da) |
| CA (1) | CA2238936C (da) |
| DE (1) | DE69607632T2 (da) |
| DK (1) | DK0850217T3 (da) |
| ES (1) | ES2145483T3 (da) |
| GR (1) | GR3033791T3 (da) |
| MX (1) | MX9801926A (da) |
| PT (1) | PT850217E (da) |
| WO (1) | WO1997010206A1 (da) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184238B1 (en) | 1996-12-26 | 2001-02-06 | Nikken Chemicals Co., Ltd. | N-hydroxyurea derivative and pharmaceutical composition containing the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5185363A (en) * | 1986-04-25 | 1993-02-09 | Abbott Laboratories | Urea based lipoxygenase inhibiting compounds |
| ATE144247T1 (de) * | 1990-07-25 | 1996-11-15 | Abbott Lab | Acetylenderivate mit lipoxygenase inhibitorischer wirkung |
| US5476873A (en) * | 1990-07-25 | 1995-12-19 | Abbott Laboratories | Acetylene derivatives having lipoxygenase inhibitory activity |
| US5288751A (en) * | 1992-11-06 | 1994-02-22 | Abbott Laboratories | [(Substituted) phenyalkyl]furylalkynyl-and [substituted) phenyalkyl] thienylalkynyl-N-hydroxyurea inhibitors or leukotriene biosynthesis |
| JP3487858B2 (ja) * | 1993-11-05 | 2004-01-19 | アボツト・ラボラトリーズ | Ｎ−［４−［（置換フェニル）アルキルチエニル］−及びｎ−４−［（置換フェニル）アルキルフリル］−ブト−３−イン−２−イル］−ｎ−ヒドロキシ尿素化合物の製造方法 |
-
1996
- 1996-08-16 US US08/698,674 patent/US5714633A/en not_active Expired - Fee Related
- 1996-08-27 CA CA002238936A patent/CA2238936C/en not_active Expired - Fee Related
- 1996-08-27 MX MX9801926A patent/MX9801926A/es unknown
- 1996-08-27 DE DE69607632T patent/DE69607632T2/de not_active Expired - Fee Related
- 1996-08-27 PT PT96931435T patent/PT850217E/pt unknown
- 1996-08-27 ES ES96931435T patent/ES2145483T3/es not_active Expired - Lifetime
- 1996-08-27 WO PCT/US1996/013892 patent/WO1997010206A1/en active IP Right Grant
- 1996-08-27 EP EP96931435A patent/EP0850217B1/en not_active Expired - Lifetime
- 1996-08-27 DK DK96931435T patent/DK0850217T3/da active
- 1996-08-27 JP JP53520796A patent/JP4400933B2/ja not_active Expired - Fee Related
- 1996-08-27 AT AT96931435T patent/ATE191466T1/de not_active IP Right Cessation
-
2000
- 2000-06-27 GR GR20000401490T patent/GR3033791T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2145483T3 (es) | 2000-07-01 |
| CA2238936C (en) | 2009-01-27 |
| ATE191466T1 (de) | 2000-04-15 |
| GR3033791T3 (en) | 2000-10-31 |
| WO1997010206A1 (en) | 1997-03-20 |
| MX9801926A (es) | 1998-05-31 |
| CA2238936A1 (en) | 1997-03-20 |
| US5714633A (en) | 1998-02-03 |
| DE69607632T2 (de) | 2000-09-21 |
| PT850217E (pt) | 2000-08-31 |
| JPH11501659A (ja) | 1999-02-09 |
| DE69607632D1 (de) | 2000-05-11 |
| EP0850217A1 (en) | 1998-07-01 |
| JP4400933B2 (ja) | 2010-01-20 |
| EP0850217B1 (en) | 2000-04-05 |
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