DK0833626T3 - Mono- og disulfosubstituerede anthraquioner og deres anvendelse til behandlingen af knoglematrixforstyrrelser - Google Patents

Mono- og disulfosubstituerede anthraquioner og deres anvendelse til behandlingen af knoglematrixforstyrrelser

Info

Publication number
DK0833626T3
DK0833626T3 DK96922001T DK96922001T DK0833626T3 DK 0833626 T3 DK0833626 T3 DK 0833626T3 DK 96922001 T DK96922001 T DK 96922001T DK 96922001 T DK96922001 T DK 96922001T DK 0833626 T3 DK0833626 T3 DK 0833626T3
Authority
DK
Denmark
Prior art keywords
treatment
bone matrix
anthraquions
disulfo
mono
Prior art date
Application number
DK96922001T
Other languages
Danish (da)
English (en)
Inventor
Sergio Rosini
Dino Benetti
Ruggero Aloisi
Giuseppe Guainai
Original Assignee
H Gen B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Gen B V filed Critical H Gen B V
Application granted granted Critical
Publication of DK0833626T3 publication Critical patent/DK0833626T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/17Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
DK96922001T 1995-06-23 1996-06-17 Mono- og disulfosubstituerede anthraquioner og deres anvendelse til behandlingen af knoglematrixforstyrrelser DK0833626T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001357A IT1276781B1 (it) 1995-06-23 1995-06-23 Derivati antrachinonmono- e disolfon- sostituiti e composizioni farmaceutiche che li contengono per il trattamento delle patologie
PCT/EP1996/002597 WO1997000675A1 (en) 1995-06-23 1996-06-17 Mono- and disulfo-substituted anthraquinones and their use for the treatment of bone matrix disorders

Publications (1)

Publication Number Publication Date
DK0833626T3 true DK0833626T3 (da) 2003-06-30

Family

ID=11371864

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96922001T DK0833626T3 (da) 1995-06-23 1996-06-17 Mono- og disulfosubstituerede anthraquioner og deres anvendelse til behandlingen af knoglematrixforstyrrelser

Country Status (16)

Country Link
US (1) US5856358A (ru)
EP (1) EP0833626B1 (ru)
JP (1) JP3307650B2 (ru)
AT (1) ATE233553T1 (ru)
AU (1) AU6303996A (ru)
CA (1) CA2225277A1 (ru)
CZ (1) CZ293326B6 (ru)
DE (1) DE69626514T2 (ru)
DK (1) DK0833626T3 (ru)
ES (1) ES2193248T3 (ru)
IT (1) IT1276781B1 (ru)
MX (1) MX9800049A (ru)
PT (1) PT833626E (ru)
RU (1) RU2202534C2 (ru)
SK (1) SK281853B6 (ru)
WO (1) WO1997000675A1 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9608133D0 (en) * 1996-04-19 1996-06-26 Gemini International Holdings Diagnostic method and apparatus
FR2757397B1 (fr) * 1996-12-23 1999-03-05 Mazal Pharma Composition pharmaceutique a base de rheine ou de diacerheine a biodisponibilite amelioree
JPH11236333A (ja) * 1997-12-30 1999-08-31 Pfizer Prod Inc 抗ガン剤として有用なイミダゾリン−4−オン誘導体
US6117869A (en) * 1998-08-04 2000-09-12 Warner-Lambert Company Compounds for and methods of inhibiting matrix metalloproteinases
US6174903B1 (en) 1998-12-28 2001-01-16 Pfizer Inc. Imidazolidin-4-one derivatives useful as anticancer agents
US6610750B1 (en) * 2000-09-15 2003-08-26 Laboratoires Negma Treatment of osteoarthritis
AUPR229600A0 (en) * 2000-12-22 2001-01-25 Commonwealth Scientific And Industrial Research Organisation New oxygen scavenging compositions
US6600057B2 (en) * 2000-12-29 2003-07-29 Kimberly-Clark Worldwide, Inc. Matrix metalloproteinase inhibitors
US8790714B2 (en) * 2007-08-03 2014-07-29 Nucitec, S.A. De C.V. Compositions and methods for treatment and prevention of osteoarthritis
CA2781706A1 (en) * 2009-11-24 2011-06-03 The Ohio State University Transcription factor inhibitors and related compositions, formulations and methods
KR101567925B1 (ko) * 2010-04-08 2015-11-10 티더블유아이 바이오테크놀로지 인코포레이티드 당뇨병 보조치료요법으로서 디아세레인을 사용하는 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2025954A (en) * 1978-07-21 1980-01-30 Ciba Geigy Ag Anthraquinone Sulphonamides
IT1244773B (it) * 1991-03-12 1994-08-08 Gentili Ist Spa N-(4,5-diidrossi-e 4,5,8-triidrossi-9,10-diidro-9,10-diosso-2- antracen-il)carbonil) amminoacidi utilizzabili nella terapia delle affezioni osteoarticolari

Also Published As

Publication number Publication date
EP0833626A1 (en) 1998-04-08
WO1997000675A1 (en) 1997-01-09
ITMI951357A0 (it) 1995-06-23
CZ293326B6 (cs) 2004-04-14
DE69626514T2 (de) 2003-12-24
CA2225277A1 (en) 1997-01-09
AU6303996A (en) 1997-01-22
SK281853B6 (sk) 2001-08-06
SK176097A3 (en) 1998-06-03
DE69626514D1 (de) 2003-04-10
EP0833626B1 (en) 2003-03-05
ATE233553T1 (de) 2003-03-15
JP3307650B2 (ja) 2002-07-24
ITMI951357A1 (it) 1996-12-23
CZ419397A3 (cs) 1998-07-15
JPH11509186A (ja) 1999-08-17
PT833626E (pt) 2003-07-31
MX9800049A (es) 1998-11-30
IT1276781B1 (it) 1997-11-03
US5856358A (en) 1999-01-05
RU2202534C2 (ru) 2003-04-20
ES2193248T3 (es) 2003-11-01

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