DK0772620T3 - Anti-messenger-oligonucleotider og urokinase-recepter-reversion af den invasive fænotype af transformerede humane fibroblas - Google Patents
Anti-messenger-oligonucleotider og urokinase-recepter-reversion af den invasive fænotype af transformerede humane fibroblasInfo
- Publication number
- DK0772620T3 DK0772620T3 DK95926907T DK95926907T DK0772620T3 DK 0772620 T3 DK0772620 T3 DK 0772620T3 DK 95926907 T DK95926907 T DK 95926907T DK 95926907 T DK95926907 T DK 95926907T DK 0772620 T3 DK0772620 T3 DK 0772620T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- oligonucleotides
- urokinase
- messenger
- prescription
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI941560A IT1271684B (it) | 1994-07-22 | 1994-07-22 | Oligonucleotidi antisenso complementari all'rna messaggero del recettore umano della urochinasi |
PCT/EP1995/002793 WO1996003414A1 (en) | 1994-07-22 | 1995-07-17 | Antimessenger oligonucleotides and urokinase receptor reversion of the invasive phenotype of transformed human fibroblasts by antimessenger oligonucleotide inhibition of urokinase receptor gene expression |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0772620T3 true DK0772620T3 (da) | 2000-03-27 |
Family
ID=11369344
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95926907T DK0772620T3 (da) | 1994-07-22 | 1995-07-17 | Anti-messenger-oligonucleotider og urokinase-recepter-reversion af den invasive fænotype af transformerede humane fibroblas |
Country Status (11)
Country | Link |
---|---|
US (1) | US5872106A (da) |
EP (1) | EP0772620B1 (da) |
JP (1) | JP3687919B2 (da) |
AT (1) | ATE185144T1 (da) |
AU (1) | AU3112395A (da) |
DE (1) | DE69512522T2 (da) |
DK (1) | DK0772620T3 (da) |
ES (1) | ES2136868T3 (da) |
GR (1) | GR3031985T3 (da) |
IT (1) | IT1271684B (da) |
WO (1) | WO1996003414A1 (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5994309A (en) | 1997-07-25 | 1999-11-30 | Angstrom Pharmaceuticals, Inc. | Anti-invasive and anti-angiogenic compositions and methods |
JP4688294B2 (ja) * | 1998-12-30 | 2011-05-25 | オリゴス・イーティーシー・インコーポレイテッド | 酸安定性骨格で修飾された末端がブロックされた核酸及びその治療的使用 |
US20050048045A1 (en) * | 2003-07-02 | 2005-03-03 | Board Of Regents, The University Of Texas System | Regulation of urokinase receptor expression by phosphoglycerate kinase |
WO2017043490A1 (ja) * | 2015-09-07 | 2017-03-16 | 協和発酵バイオ株式会社 | 自然免疫誘導効果が増強した二重鎖リボ核酸 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69033653T2 (de) * | 1989-04-07 | 2001-06-07 | Cancerforskningsfonden Af 1989 | Plasminogen-aktivator-rezeptor vom urokinasetyp |
-
1994
- 1994-07-22 IT ITMI941560A patent/IT1271684B/it active IP Right Grant
-
1995
- 1995-07-17 JP JP50542496A patent/JP3687919B2/ja not_active Expired - Fee Related
- 1995-07-17 DK DK95926907T patent/DK0772620T3/da active
- 1995-07-17 US US08/776,062 patent/US5872106A/en not_active Expired - Fee Related
- 1995-07-17 AT AT95926907T patent/ATE185144T1/de not_active IP Right Cessation
- 1995-07-17 WO PCT/EP1995/002793 patent/WO1996003414A1/en active IP Right Grant
- 1995-07-17 EP EP95926907A patent/EP0772620B1/en not_active Expired - Lifetime
- 1995-07-17 AU AU31123/95A patent/AU3112395A/en not_active Abandoned
- 1995-07-17 ES ES95926907T patent/ES2136868T3/es not_active Expired - Lifetime
- 1995-07-17 DE DE69512522T patent/DE69512522T2/de not_active Expired - Fee Related
-
1999
- 1999-11-29 GR GR990403078T patent/GR3031985T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU3112395A (en) | 1996-02-22 |
ITMI941560A0 (it) | 1994-07-22 |
DE69512522D1 (de) | 1999-11-04 |
DE69512522T2 (de) | 2000-01-13 |
JP3687919B2 (ja) | 2005-08-24 |
JPH10502823A (ja) | 1998-03-17 |
ATE185144T1 (de) | 1999-10-15 |
EP0772620B1 (en) | 1999-09-29 |
GR3031985T3 (en) | 2000-03-31 |
ES2136868T3 (es) | 1999-12-01 |
EP0772620A1 (en) | 1997-05-14 |
ITMI941560A1 (it) | 1996-01-22 |
US5872106A (en) | 1999-02-16 |
WO1996003414A1 (en) | 1996-02-08 |
IT1271684B (it) | 1997-06-04 |
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