DK0766577T3 - Device for sampling substances using alternating polarity - Google Patents

Device for sampling substances using alternating polarity

Info

Publication number
DK0766577T3
DK0766577T3 DK95924591T DK95924591T DK0766577T3 DK 0766577 T3 DK0766577 T3 DK 0766577T3 DK 95924591 T DK95924591 T DK 95924591T DK 95924591 T DK95924591 T DK 95924591T DK 0766577 T3 DK0766577 T3 DK 0766577T3
Authority
DK
Denmark
Prior art keywords
sampling
substance
chambers
polarity
subject
Prior art date
Application number
DK95924591T
Other languages
Danish (da)
Inventor
Janet Tamada
Original Assignee
Cygnus Therapeutic Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Cygnus Therapeutic Systems filed Critical Cygnus Therapeutic Systems
Application granted granted Critical
Publication of DK0766577T3 publication Critical patent/DK0766577T3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6832—Means for maintaining contact with the body using adhesives
    • A61B5/6833—Adhesive patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Emergency Medicine (AREA)
  • Optics & Photonics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Electrolytic Production Of Metals (AREA)
  • Amplifiers (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

A method for sampling of a substance from a subject is provided, which comprises placing one or more sampling chambers on a collection site on a tissue surface on the subject; conducting electric current through the tissue to extract a substance from the subject in a first direction in one or more sampling chambers that functions alternatively as both an anode and cathode during the course of the method; reversing the polarity to cause direct current to flow in second direction opposite the first direction; and analyzing the sampling chamber or chambers for the concentration of a substance or a substance metabolite. There is also provided a device for sampling of a substance from an organism on continuously or intermittently using alternating polarity method based on the application of low intensity electric fields of alternating polarity across the skin (iontophoresis) to enhance the transport of a substance (such as glucose, lactic acid, pyruvic acid, and the like) from body tissues to a sampling chamber. The device comprises an electrical power supply; a transdermal system that contains one or more sampling chambers that function as both anode and cathode during the course of sampling; a means to alternates or reverses the polarity during the iontophoretic sampling; and means for analyzing for the concentration of a substance or a substance metabolite.
DK95924591T 1994-06-24 1995-06-23 Device for sampling substances using alternating polarity DK0766577T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/265,844 US5771890A (en) 1994-06-24 1994-06-24 Device and method for sampling of substances using alternating polarity
PCT/US1995/007579 WO1996000109A1 (en) 1994-06-24 1995-06-23 Device and method for sampling of substances using alternating polarity

Publications (1)

Publication Number Publication Date
DK0766577T3 true DK0766577T3 (en) 2004-03-22

Family

ID=23012093

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95924591T DK0766577T3 (en) 1994-06-24 1995-06-23 Device for sampling substances using alternating polarity

Country Status (11)

Country Link
US (4) US5771890A (en)
EP (1) EP0766577B1 (en)
JP (1) JP3350053B2 (en)
AT (1) ATE255936T1 (en)
AU (1) AU2902695A (en)
CA (1) CA2193884C (en)
DE (1) DE69532282T2 (en)
DK (1) DK0766577T3 (en)
ES (1) ES2211909T3 (en)
PT (1) PT766577E (en)
WO (1) WO1996000109A1 (en)

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EP0766577B1 (en) 2003-12-10
CA2193884A1 (en) 1996-01-04
JPH10505761A (en) 1998-06-09
DE69532282T2 (en) 2004-12-09
ES2211909T3 (en) 2004-07-16
WO1996000109A1 (en) 1996-01-04
AU2902695A (en) 1996-01-19
US20020002328A1 (en) 2002-01-03
EP0766577A1 (en) 1997-04-09
US6298254B2 (en) 2001-10-02
US5771890A (en) 1998-06-30
US20010020124A1 (en) 2001-09-06
PT766577E (en) 2004-03-31
ATE255936T1 (en) 2003-12-15
US6687522B2 (en) 2004-02-03
US6023629A (en) 2000-02-08
JP3350053B2 (en) 2002-11-25
DE69532282D1 (en) 2004-01-22
CA2193884C (en) 2002-08-20

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