DK0763516T3 - Fremstilling og anvendelse af rene enantiomerer af 8-halogen-6-hydroxyoctansyrer, deres alkylestere og deres salte med rene enantiomerer af alfa-methylbenzylamin - Google Patents

Fremstilling og anvendelse af rene enantiomerer af 8-halogen-6-hydroxyoctansyrer, deres alkylestere og deres salte med rene enantiomerer af alfa-methylbenzylamin

Info

Publication number
DK0763516T3
DK0763516T3 DK96114418T DK96114418T DK0763516T3 DK 0763516 T3 DK0763516 T3 DK 0763516T3 DK 96114418 T DK96114418 T DK 96114418T DK 96114418 T DK96114418 T DK 96114418T DK 0763516 T3 DK0763516 T3 DK 0763516T3
Authority
DK
Denmark
Prior art keywords
pure enantiomers
halo
methylbenzylamine
alpha
salts
Prior art date
Application number
DK96114418T
Other languages
English (en)
Inventor
Dr Gewald Rainer
Dr Laban Gunter
Dr Beisswenger Thomas
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Application granted granted Critical
Publication of DK0763516T3 publication Critical patent/DK0763516T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
    • C07C59/115—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
DK96114418T 1995-09-13 1996-09-10 Fremstilling og anvendelse af rene enantiomerer af 8-halogen-6-hydroxyoctansyrer, deres alkylestere og deres salte med rene enantiomerer af alfa-methylbenzylamin DK0763516T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19533882A DE19533882A1 (de) 1995-09-13 1995-09-13 Herstellung und Verwendung der reinen Enantiomere der 8-Halogen-6-hydroxyoctansäuren, ihrer Alkylester und ihrer Salze mit reinen Enantiomeren des alpha-Methylbenzylamins

Publications (1)

Publication Number Publication Date
DK0763516T3 true DK0763516T3 (da) 2001-09-17

Family

ID=7772034

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96114418T DK0763516T3 (da) 1995-09-13 1996-09-10 Fremstilling og anvendelse af rene enantiomerer af 8-halogen-6-hydroxyoctansyrer, deres alkylestere og deres salte med rene enantiomerer af alfa-methylbenzylamin

Country Status (10)

Country Link
US (1) US5869713A (da)
EP (1) EP0763516B1 (da)
JP (1) JPH09169692A (da)
AT (1) ATE202332T1 (da)
DE (2) DE19533882A1 (da)
DK (1) DK0763516T3 (da)
ES (1) ES2159665T3 (da)
GR (1) GR3036631T3 (da)
PT (1) PT763516E (da)
RU (1) RU2175965C2 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10137381A1 (de) 2001-07-31 2003-02-13 Viatris Gmbh Neue Modifikationen des Trometamolsalzes der R-Thioctsäure sowie Verfahren zu ihrer Herstellung
DE10152113C1 (de) 2001-10-23 2003-03-06 Viatris Gmbh Verfahren zur Herstellung von (R)- und (S)-8-Chlor-6-hydroxy-octansäurealkylestern durch enzymatische Reduktion

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2980716A (en) * 1954-06-11 1961-04-18 Research Corp Method for preparing 6, 8-dihalooctanoic esters
US2975198A (en) * 1954-07-08 1961-03-14 Research Corp Lipoic acid intermediates
EP0812590A3 (de) 1989-11-09 1999-06-09 ASTA Medica Aktiengesellschaft Verwendung von R-Alpha-Liponsäure zur Zytoprotektion
DE4037440A1 (de) 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
DE4137773A1 (de) * 1991-11-16 1993-05-19 Degussa Herstellung und verwendung von salzen der reinen enantiomere der (alpha)-liponsaeure

Also Published As

Publication number Publication date
DE19533882A1 (de) 1997-03-20
ATE202332T1 (de) 2001-07-15
EP0763516B1 (de) 2001-06-20
RU2175965C2 (ru) 2001-11-20
ES2159665T3 (es) 2001-10-16
GR3036631T3 (en) 2001-12-31
DE59607119D1 (de) 2001-07-26
PT763516E (pt) 2001-11-30
US5869713A (en) 1999-02-09
EP0763516A1 (de) 1997-03-19
JPH09169692A (ja) 1997-06-30

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