DK0749482T3 - Rekombinante humaniserede anti-Lewis Y antistoffer - Google Patents

Rekombinante humaniserede anti-Lewis Y antistoffer

Info

Publication number
DK0749482T3
DK0749482T3 DK95912894T DK95912894T DK0749482T3 DK 0749482 T3 DK0749482 T3 DK 0749482T3 DK 95912894 T DK95912894 T DK 95912894T DK 95912894 T DK95912894 T DK 95912894T DK 0749482 T3 DK0749482 T3 DK 0749482T3
Authority
DK
Denmark
Prior art keywords
lewis
humanized
antibodies
specific antibodies
antigen
Prior art date
Application number
DK95912894T
Other languages
English (en)
Inventor
Dr Kathryn Armour
Pilar Garin-Chesa
Thomas P Wallace
William J Harris
Francis J Carr
Lloyd J Old
Elisabeth Stockert
Sydney Welt
Kunio Kitamura
Original Assignee
Sloan Kettering Inst Cancer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sloan Kettering Inst Cancer filed Critical Sloan Kettering Inst Cancer
Application granted granted Critical
Publication of DK0749482T3 publication Critical patent/DK0749482T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK95912894T 1994-03-08 1995-03-08 Rekombinante humaniserede anti-Lewis Y antistoffer DK0749482T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/207,861 US6310185B1 (en) 1994-03-08 1994-03-08 Recombinant human anti-Lewis Y antibodies
PCT/US1995/003096 WO1995024484A1 (en) 1994-03-08 1995-03-08 Recombinant humanized anti-lewis y antibodies

Publications (1)

Publication Number Publication Date
DK0749482T3 true DK0749482T3 (da) 2003-09-29

Family

ID=22772277

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95912894T DK0749482T3 (da) 1994-03-08 1995-03-08 Rekombinante humaniserede anti-Lewis Y antistoffer

Country Status (10)

Country Link
US (3) US6310185B1 (da)
EP (1) EP0749482B1 (da)
AT (1) ATE242326T1 (da)
AU (1) AU696286B2 (da)
CA (1) CA2185114C (da)
DE (1) DE69530975T2 (da)
DK (1) DK0749482T3 (da)
ES (1) ES2199985T3 (da)
PT (1) PT749482E (da)
WO (1) WO1995024484A1 (da)

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US6310185B1 (en) * 1994-03-08 2001-10-30 Memorial Sloan Kettering Cancer Center Recombinant human anti-Lewis Y antibodies
US7118493B2 (en) * 1999-11-01 2006-10-10 Callaway Golf Company Multiple material golf club head
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US6739983B2 (en) * 1999-11-01 2004-05-25 Callaway Golf Company Golf club head with customizable center of gravity
TW577761B (en) 1999-11-01 2004-03-01 Callaway Golf Co Multiple material golf club head
US6663504B2 (en) 1999-11-01 2003-12-16 Callaway Golf Company Multiple material golf club head
US7128661B2 (en) * 1999-11-01 2006-10-31 Callaway Golf Company Multiple material golf club head
US7125344B2 (en) * 1999-11-01 2006-10-24 Callaway Golf Company Multiple material golf club head
US6491592B2 (en) 1999-11-01 2002-12-10 Callaway Golf Company Multiple material golf club head
US6582323B2 (en) 1999-11-01 2003-06-24 Callaway Golf Company Multiple material golf club head
CZ20032208A3 (cs) * 2001-02-23 2004-01-14 Immunex Corporation Zvýšený výtěžek aktivních proteinů
SG187991A1 (en) 2002-05-02 2013-03-28 Wyeth Corp Calicheamicin derivative-carrier conjugates
EP2322209A3 (en) 2002-08-20 2012-02-01 Glykos Finland Oy Tumor specific oligosaccharide epitopes and use thereof
US6984181B2 (en) * 2002-09-25 2006-01-10 Callaway Golf Company Multiple material golf putter head
JP4206915B2 (ja) * 2002-12-27 2009-01-14 三菱マテリアル株式会社 パワーモジュール用基板
US20060011388A1 (en) * 2003-01-31 2006-01-19 Mohammed Boudrare Drill bit and cutter element having multiple extensions
US6929079B2 (en) * 2003-02-21 2005-08-16 Smith International, Inc. Drill bit cutter element having multiple cusps
US6883624B2 (en) * 2003-01-31 2005-04-26 Smith International, Inc. Multi-lobed cutter element for drill bit
EP1660538A1 (en) * 2003-08-14 2006-05-31 Wyeth Anti-lewis y anti-idiotypic antibodies and uses thereof
AR048098A1 (es) * 2004-03-15 2006-03-29 Wyeth Corp Conjugados de caliqueamicina
US7300773B2 (en) * 2004-08-27 2007-11-27 Wyeth Research Ireland Limited Production of TNFR-Ig
TWI384069B (zh) * 2004-08-27 2013-02-01 Pfizer Ireland Pharmaceuticals 多胜肽之製法
RU2451082C2 (ru) * 2004-08-27 2012-05-20 Вайет Рисёрч Айрлэнд Лимитед Производство полипептидов
TWI374935B (en) * 2004-08-27 2012-10-21 Pfizer Ireland Pharmaceuticals Production of α-abeta
US7549935B2 (en) * 2005-01-03 2009-06-23 Callaway Golf Company Golf club head
US7166038B2 (en) * 2005-01-03 2007-01-23 Callaway Golf Company Golf club head
US7591737B2 (en) * 2005-01-03 2009-09-22 Callaway Golf Company Golf club head
US7559851B2 (en) * 2005-01-03 2009-07-14 Callaway Golf Company Golf club with high moment of inertia
US7169060B2 (en) 2005-01-03 2007-01-30 Callaway Golf Company Golf club head
US7568982B2 (en) 2005-01-03 2009-08-04 Callaway Golf Company Golf club with high moment of inertia
US7311613B2 (en) * 2005-01-03 2007-12-25 Callaway Golf Company Golf club head
US7163468B2 (en) 2005-01-03 2007-01-16 Callaway Golf Company Golf club head
US7488261B2 (en) * 2005-01-03 2009-02-10 Callaway Golf Company Golf club with high moment of inertia
US20080206239A1 (en) 2005-02-03 2008-08-28 Antitope Limited Human Antibodies And Proteins
US7690442B2 (en) * 2005-05-17 2010-04-06 Smith International, Inc. Drill bit and cutting inserts for hard/abrasive formations
US7757789B2 (en) * 2005-06-21 2010-07-20 Smith International, Inc. Drill bit and insert having bladed interface between substrate and coating
FI20055417A0 (fi) 2005-07-20 2005-07-20 Glykos Finland Oy Syöpäpesifiset glykaanit ja niiden käyttö
US8883162B2 (en) 2005-10-19 2014-11-11 Ibc Pharmaceuticals, Inc. Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors
US9862770B2 (en) 2005-10-19 2018-01-09 Ibc Pharmaceuticals, Inc. Multivalent antibody complexes targeting IGF-1R show potent toxicity against solid tumors
US20100226884A1 (en) 2009-01-20 2010-09-09 Immunomedics, Inc. Novel Class of Monospecific and Bispecific Humanized Antibodies that Target the Insulin-like Growth Factor Type I Receptor (IGF-1R)
CA2628756A1 (en) * 2005-12-06 2007-06-14 Wyeth Interleukin-11 compositions and methods of use
SG170091A1 (en) 2006-03-10 2011-04-29 Wyeth Corp Anti-5t4 antibodies and uses thereof
EP2012586A4 (en) * 2006-04-10 2010-08-18 Abbott Biotech Ltd USES AND COMPOSITIONS FOR THE TREATMENT OF ANKYLOSANTE SPONDYLARTHRITIS
US20100021451A1 (en) 2006-06-08 2010-01-28 Wong Robert L Uses and compositions for treatment of ankylosing spondylitis
US7743855B2 (en) * 2006-09-05 2010-06-29 Smith International, Inc. Drill bit with cutter element having multifaceted, slanted top cutting surface
US7798258B2 (en) * 2007-01-03 2010-09-21 Smith International, Inc. Drill bit with cutter element having crossing chisel crests
US8205692B2 (en) * 2007-01-03 2012-06-26 Smith International, Inc. Rock bit and inserts with a chisel crest having a broadened region
US7631709B2 (en) 2007-01-03 2009-12-15 Smith International, Inc. Drill bit and cutter element having chisel crest with protruding pilot portion
US7686106B2 (en) * 2007-01-03 2010-03-30 Smith International, Inc. Rock bit and inserts with wear relief grooves
US7819754B2 (en) * 2007-09-13 2010-10-26 Callaway Golf Company Golf club with removable components
US7753809B2 (en) * 2007-12-19 2010-07-13 Cackett Matthew T Driver with deep AFT cavity
US8414422B2 (en) * 2009-12-16 2013-04-09 Callaway Golf Company External weight for golf club head
EP2525820B1 (en) * 2010-01-19 2016-05-11 Immunomedics, Inc. Novel class of monospecific and bispecific humanized antibodies that target the insulin-like growth factor type i receptor (igf-1r)
EP2606119A1 (en) 2010-08-20 2013-06-26 Wyeth LLC Cell culture of growth factor-free adapted cells
US8607899B2 (en) 2011-02-18 2013-12-17 National Oilwell Varco, L.P. Rock bit and cutter teeth geometries
WO2013006479A2 (en) 2011-07-01 2013-01-10 Amgen Inc. Mammalian cell culture
WO2013057628A1 (en) 2011-10-21 2013-04-25 Pfizer Inc. Addition of iron to improve cell culture
GB201910899D0 (en) * 2019-07-31 2019-09-11 Scancell Ltd Binding members
CN113214402B (zh) * 2021-06-03 2022-06-07 上海交通大学 分离的抗原结合蛋白及其应用

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US5225539A (en) * 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
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US5242824A (en) * 1988-12-22 1993-09-07 Oncogen Monoclonal antibody to human carcinomas
IL94872A (en) * 1989-06-30 1995-03-30 Oncogen Monoclonal or chimeric antibodies that react with human carcinoma, recombinant proteins that contain their anti-binding site, pharmaceutical preparations and kits that contain the
GB9019812D0 (en) * 1990-09-11 1990-10-24 Scotgen Ltd Novel antibodies for treatment and prevention of infection in animals and man
ATE188708T1 (de) * 1991-08-21 2000-01-15 Novartis Ag Antikörperderivate
US6310185B1 (en) * 1994-03-08 2001-10-30 Memorial Sloan Kettering Cancer Center Recombinant human anti-Lewis Y antibodies

Also Published As

Publication number Publication date
US6518415B1 (en) 2003-02-11
EP0749482A1 (en) 1996-12-27
EP0749482B1 (en) 2003-06-04
WO1995024484A1 (en) 1995-09-14
US5874060A (en) 1999-02-23
DE69530975T2 (de) 2004-05-19
AU696286B2 (en) 1998-09-03
CA2185114A1 (en) 1995-09-14
ATE242326T1 (de) 2003-06-15
US6310185B1 (en) 2001-10-30
PT749482E (pt) 2003-10-31
AU1990795A (en) 1995-09-25
ES2199985T3 (es) 2004-03-01
DE69530975D1 (de) 2003-07-10
CA2185114C (en) 2008-01-22

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