DK0740657T3 - 4-Arylisoindoler med analgetisk virkning - Google Patents
4-Arylisoindoler med analgetisk virkningInfo
- Publication number
- DK0740657T3 DK0740657T3 DK95904262T DK95904262T DK0740657T3 DK 0740657 T3 DK0740657 T3 DK 0740657T3 DK 95904262 T DK95904262 T DK 95904262T DK 95904262 T DK95904262 T DK 95904262T DK 0740657 T3 DK0740657 T3 DK 0740657T3
- Authority
- DK
- Denmark
- Prior art keywords
- arylisoindoles
- analgesic effect
- image
- alkylcarbonyloxy
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/173,326 US5543530A (en) | 1993-12-23 | 1993-12-23 | 4-arylisoindole analgesics |
| PCT/US1994/014050 WO1995017384A1 (en) | 1993-12-23 | 1994-12-02 | 4-arylisoindole analgesics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0740657T3 true DK0740657T3 (da) | 2002-06-24 |
Family
ID=22631518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK95904262T DK0740657T3 (da) | 1993-12-23 | 1994-12-02 | 4-Arylisoindoler med analgetisk virkning |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5543530A (da) |
| EP (1) | EP0740657B1 (da) |
| JP (1) | JP3541952B2 (da) |
| AT (1) | ATE214049T1 (da) |
| AU (1) | AU700505B2 (da) |
| CA (1) | CA2179634C (da) |
| DE (1) | DE69430074T2 (da) |
| DK (1) | DK0740657T3 (da) |
| ES (1) | ES2173169T3 (da) |
| IL (1) | IL112110A0 (da) |
| MX (1) | MX9500231A (da) |
| PT (1) | PT740657E (da) |
| WO (1) | WO1995017384A1 (da) |
| ZA (1) | ZA9410280B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5541217A (en) * | 1995-05-17 | 1996-07-30 | Ortho Pharmaceutical Corporation | 4-arylcyclopenta[c]pyrrole analgesics |
| US5602167A (en) * | 1995-05-17 | 1997-02-11 | Ortho Pharmaceutical Corporation | 4-arylcyclohepta[c] pyrrole analgesics |
| MXPA05001726A (es) * | 2002-08-14 | 2005-05-27 | Abbott Lab | Compuestos azabiciclicos son agentes activos del sistema nervioso central. |
| US7135484B2 (en) | 2002-08-14 | 2006-11-14 | Abbott Laboratories | Azabicyclic compounds are central nervous system active agents |
| CN102911108A (zh) * | 2012-11-16 | 2013-02-06 | 葛长乐 | 一种反式全氢异吲哚及其盐的制备方法 |
| JP7390401B2 (ja) * | 2019-05-30 | 2023-12-01 | シャンハイ インスティテュート オブ マテリア メディカ、チャイニーズ アカデミー オブ サイエンシーズ | 縮合環化合物、その製造方法及び用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4042707A (en) * | 1976-02-19 | 1977-08-16 | E. I. Du Pont De Nemours And Company | 3α-Arylhydroisoindoles |
| US4689329A (en) * | 1986-02-04 | 1987-08-25 | Mcneilab, Inc. | 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates |
| FR2654726B1 (fr) * | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone et leur preparation. |
| US5216018A (en) * | 1992-02-14 | 1993-06-01 | Du Pont Merck Pharmaceutical Company | Hydroisoindolines and hydroisoquinolines as psychotropic |
| US5508424A (en) * | 1993-03-26 | 1996-04-16 | Ortho Pharmaceutical Corporation | 4-arylisoindole analgesics |
-
1993
- 1993-12-23 US US08/173,326 patent/US5543530A/en not_active Expired - Lifetime
-
1994
- 1994-12-02 AU AU13018/95A patent/AU700505B2/en not_active Expired
- 1994-12-02 WO PCT/US1994/014050 patent/WO1995017384A1/en active IP Right Grant
- 1994-12-02 JP JP51745095A patent/JP3541952B2/ja not_active Expired - Lifetime
- 1994-12-02 DE DE69430074T patent/DE69430074T2/de not_active Expired - Lifetime
- 1994-12-02 PT PT95904262T patent/PT740657E/pt unknown
- 1994-12-02 CA CA002179634A patent/CA2179634C/en not_active Expired - Lifetime
- 1994-12-02 AT AT95904262T patent/ATE214049T1/de active
- 1994-12-02 EP EP95904262A patent/EP0740657B1/en not_active Expired - Lifetime
- 1994-12-02 ES ES95904262T patent/ES2173169T3/es not_active Expired - Lifetime
- 1994-12-02 DK DK95904262T patent/DK0740657T3/da active
- 1994-12-22 IL IL11211094A patent/IL112110A0/xx unknown
- 1994-12-22 ZA ZA9410280A patent/ZA9410280B/xx unknown
-
1995
- 1995-01-02 MX MX9500231A patent/MX9500231A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU1301895A (en) | 1995-07-10 |
| DE69430074T2 (de) | 2002-09-05 |
| MX9500231A (es) | 1997-02-28 |
| ATE214049T1 (de) | 2002-03-15 |
| DE69430074D1 (de) | 2002-04-11 |
| PT740657E (pt) | 2002-07-31 |
| US5543530A (en) | 1996-08-06 |
| CA2179634A1 (en) | 1995-06-29 |
| JP3541952B2 (ja) | 2004-07-14 |
| WO1995017384A1 (en) | 1995-06-29 |
| JPH09507064A (ja) | 1997-07-15 |
| ZA9410280B (en) | 1996-06-24 |
| AU700505B2 (en) | 1999-01-07 |
| EP0740657B1 (en) | 2002-03-06 |
| ES2173169T3 (es) | 2002-10-16 |
| CA2179634C (en) | 2005-09-13 |
| EP0740657A1 (en) | 1996-11-06 |
| IL112110A0 (en) | 1995-03-15 |
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