DK0700395T3 - Indolderivater som steroid 5-alfa-reduktase-inhibitorer - Google Patents
Indolderivater som steroid 5-alfa-reduktase-inhibitorerInfo
- Publication number
- DK0700395T3 DK0700395T3 DK94917676.2T DK94917676T DK0700395T3 DK 0700395 T3 DK0700395 T3 DK 0700395T3 DK 94917676 T DK94917676 T DK 94917676T DK 0700395 T3 DK0700395 T3 DK 0700395T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- steroid
- reductase inhibitors
- indole derivatives
- alpha reductase
- Prior art date
Links
- 239000002677 5-alpha reductase inhibitor Substances 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 108010029908 3-oxo-5-alpha-steroid 4-dehydrogenase Proteins 0.000 abstract 1
- 102000001779 3-oxo-5-alpha-steroid 4-dehydrogenase Human genes 0.000 abstract 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004299 tetrazol-5-yl group Chemical group [H]N1N=NC(*)=N1 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939311008A GB9311008D0 (en) | 1993-05-28 | 1993-05-28 | Indoles |
| GB939317529A GB9317529D0 (en) | 1993-05-28 | 1993-08-20 | Indoles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0700395T3 true DK0700395T3 (da) | 1997-10-13 |
Family
ID=26302960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94917676.2T DK0700395T3 (da) | 1993-05-28 | 1994-05-26 | Indolderivater som steroid 5-alfa-reduktase-inhibitorer |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US5696146A (da) |
| EP (1) | EP0700395B1 (da) |
| JP (1) | JP2757969B2 (da) |
| AT (1) | ATE154352T1 (da) |
| AU (1) | AU6930494A (da) |
| CA (1) | CA2163778C (da) |
| DE (1) | DE69403793T2 (da) |
| DK (1) | DK0700395T3 (da) |
| ES (1) | ES2102863T3 (da) |
| FI (1) | FI113864B (da) |
| GR (1) | GR3024366T3 (da) |
| HU (1) | HU9501935D0 (da) |
| IL (1) | IL109728A0 (da) |
| WO (1) | WO1994027990A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9204365D0 (en) * | 1992-02-28 | 1992-04-08 | Pfizer Ltd | Indoles |
| GB9317096D0 (en) * | 1993-08-17 | 1993-09-29 | Pfizer Ltd | Indoles |
| RU2009116632A (ru) | 2006-10-02 | 2010-11-10 | Кортендо Инвест, Аб (Se) | Энантиомер кетоконазола у людей |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9011335D0 (en) * | 1990-05-21 | 1990-07-11 | Fujisawa Pharmaceutical Co | Indolebutyric acid derivatives and process for preparation thereof |
| GB9204365D0 (en) * | 1992-02-28 | 1992-04-08 | Pfizer Ltd | Indoles |
| GB9317096D0 (en) * | 1993-08-17 | 1993-09-29 | Pfizer Ltd | Indoles |
-
1994
- 1994-05-23 IL IL10972894A patent/IL109728A0/xx unknown
- 1994-05-26 DK DK94917676.2T patent/DK0700395T3/da active
- 1994-05-26 ES ES94917676T patent/ES2102863T3/es not_active Expired - Lifetime
- 1994-05-26 HU HU9501935A patent/HU9501935D0/hu unknown
- 1994-05-26 US US08/553,589 patent/US5696146A/en not_active Expired - Fee Related
- 1994-05-26 AT AT94917676T patent/ATE154352T1/de not_active IP Right Cessation
- 1994-05-26 EP EP94917676A patent/EP0700395B1/en not_active Expired - Lifetime
- 1994-05-26 WO PCT/EP1994/001760 patent/WO1994027990A1/en active IP Right Grant
- 1994-05-26 AU AU69304/94A patent/AU6930494A/en not_active Abandoned
- 1994-05-26 DE DE69403793T patent/DE69403793T2/de not_active Expired - Fee Related
- 1994-05-26 CA CA002163778A patent/CA2163778C/en not_active Expired - Fee Related
- 1994-05-26 JP JP7500251A patent/JP2757969B2/ja not_active Expired - Lifetime
-
1995
- 1995-11-27 FI FI955707A patent/FI113864B/fi not_active IP Right Cessation
-
1997
- 1997-08-06 GR GR970402013T patent/GR3024366T3/el unknown
- 1997-12-02 US US08/982,735 patent/US5922747A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2163778A1 (en) | 1994-12-08 |
| AU6930494A (en) | 1994-12-20 |
| CA2163778C (en) | 1999-04-27 |
| EP0700395B1 (en) | 1997-06-11 |
| DE69403793D1 (de) | 1997-07-17 |
| FI955707A (fi) | 1995-11-27 |
| US5696146A (en) | 1997-12-09 |
| JP2757969B2 (ja) | 1998-05-25 |
| GR3024366T3 (en) | 1997-11-28 |
| IL109728A0 (en) | 1994-08-26 |
| FI113864B (fi) | 2004-06-30 |
| US5922747A (en) | 1999-07-13 |
| ATE154352T1 (de) | 1997-06-15 |
| EP0700395A1 (en) | 1996-03-13 |
| WO1994027990A1 (en) | 1994-12-08 |
| JPH08506350A (ja) | 1996-07-09 |
| FI955707A0 (fi) | 1995-11-27 |
| ES2102863T3 (es) | 1997-08-01 |
| DE69403793T2 (de) | 1997-09-25 |
| HU9501935D0 (en) | 1995-09-28 |
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