DK0692962T3 - Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme - Google Patents

Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme

Info

Publication number
DK0692962T3
DK0692962T3 DK94912437T DK94912437T DK0692962T3 DK 0692962 T3 DK0692962 T3 DK 0692962T3 DK 94912437 T DK94912437 T DK 94912437T DK 94912437 T DK94912437 T DK 94912437T DK 0692962 T3 DK0692962 T3 DK 0692962T3
Authority
DK
Denmark
Prior art keywords
steroid
antagonists
receptor
prophylaxis
therapy
Prior art date
Application number
DK94912437T
Other languages
Danish (da)
English (en)
Inventor
Rainer Denecke
Original Assignee
Altramed Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altramed Holdings Ltd filed Critical Altramed Holdings Ltd
Application granted granted Critical
Publication of DK0692962T3 publication Critical patent/DK0692962T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94912437T 1993-04-10 1994-03-30 Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme DK0692962T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4311870A DE4311870C2 (de) 1993-04-10 1993-04-10 Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen
PCT/DE1994/000366 WO1994023708A1 (fr) 1993-04-10 1994-03-30 Utilisation d'antagonistes steroïdiens pour le traitement et la prophylaxie de maladies du type demence

Publications (1)

Publication Number Publication Date
DK0692962T3 true DK0692962T3 (da) 1998-09-28

Family

ID=6485255

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94912437T DK0692962T3 (da) 1993-04-10 1994-03-30 Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme

Country Status (11)

Country Link
US (2) US6232350B1 (fr)
EP (2) EP0692962B1 (fr)
JP (1) JPH08508507A (fr)
AT (1) ATE163543T1 (fr)
AU (1) AU690110B2 (fr)
CA (1) CA2160132C (fr)
DE (2) DE4311870C2 (fr)
DK (1) DK0692962T3 (fr)
ES (1) ES2114188T3 (fr)
GR (1) GR3026392T3 (fr)
WO (1) WO1994023708A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0735821A4 (fr) * 1993-12-21 1998-04-01 Lilly Co Eli Procedes permettant de traiter ou de prevenir les pathologies associees aux peptides amylo dogenes
US5552415A (en) * 1993-12-21 1996-09-03 Eli Lilly And Company Method of inhibiting Alzheimer's Disease
US6562862B1 (en) * 1994-10-20 2003-05-13 Eli Lilly And Company Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
CZ212097A3 (en) * 1995-01-20 1997-11-12 Novo Nordisk As Use of 3,4-diphenylchromans for preparing a medicament intended for treating or prophylaxis of cerebral degenerative diseases
HUP0002852A3 (en) 1997-08-15 2001-11-28 Univ Durham A method of preventing or treating estrogen-dependent diseases and disorders using triphenil-ethylene derivatives
GB9824207D0 (en) * 1998-11-04 1998-12-30 Zeneca Ltd Neurological disorders
AR027878A1 (es) * 1999-11-05 2003-04-16 Wyeth Corp Metodos para identificar y utilizar compuestos inhibidores de amiloides
US7067550B2 (en) * 2000-11-03 2006-06-27 Massachusetts Institute Of Technology Treatments for neurotoxicity in Alzheimer's Disease
WO2005105063A1 (fr) * 2004-05-03 2005-11-10 Universita' Degli Studi Di Firenze Compositions pharmaceutiques contenant des s.e.r.m. et utilisees dans le traitement de la maladie d'alzheimer
ES2428313T3 (es) 2005-03-24 2013-11-07 Emory University Métodos para el tratamiento de lesiones del sistema nervioso central mediante un protocolo de administración decreciente
US7473687B2 (en) 2005-03-24 2009-01-06 Emory University Methods for the treatment of a traumatic central nervous system injury

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3046719C2 (de) * 1980-12-11 1983-02-17 Klinge Pharma GmbH, 8000 München 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
US5491173A (en) * 1982-06-25 1996-02-13 Orion-Yhtyma Oy Tri-phenyl alkene derivatives and their preparation and use
US4791099A (en) * 1984-10-29 1988-12-13 Chaovanee Aroonsakul Method of treatment for central nervous system diseases such as Alzheimer's's disease
ES2078890T3 (es) * 1986-10-09 1996-01-01 Upjohn Co Amino esteroides en c20 a c26.
GB9207437D0 (en) * 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites
CA2134772A1 (fr) * 1992-05-01 1993-11-11 Btg International Limited 1,1,2-triphenylbutenes substitues et leur utilisation pour le traitement et le diagnostic du cancer
US5264619B1 (en) * 1993-01-15 1996-05-14 Cosmos Pharm Corp Anti-androgenic cyclo and bicyclo alkenes
US5455275A (en) * 1994-05-11 1995-10-03 Eli Lilly And Company Methods for inhibiting endometriosis and uterine fibroid disease with 1,1,2-triphenylbut-1-ene derivatives
US5470883A (en) * 1994-05-23 1995-11-28 Stromberg; Brent V. Method of treating peripheral vasoconstriction with tamoxifen citrate
IL120269A0 (en) * 1996-02-28 1997-06-10 Pfizer 1,1,2-triphenylbut-1-ene derivatives for treating Alzheimer's disease

Also Published As

Publication number Publication date
GR3026392T3 (en) 1998-06-30
EP0797990A2 (fr) 1997-10-01
CA2160132A1 (fr) 1994-10-27
DE59405394D1 (de) 1998-04-09
DE4311870A1 (de) 1994-10-13
JPH08508507A (ja) 1996-09-10
ES2114188T3 (es) 1998-05-16
DE4311870C2 (de) 1998-07-30
EP0692962A1 (fr) 1996-01-24
EP0797990A3 (fr) 1997-10-08
EP0692962B1 (fr) 1998-03-04
US6232350B1 (en) 2001-05-15
AU6501494A (en) 1994-11-08
US20010018434A1 (en) 2001-08-30
WO1994023708A1 (fr) 1994-10-27
ATE163543T1 (de) 1998-03-15
AU690110B2 (en) 1998-04-23
CA2160132C (fr) 2002-01-15

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