DK0692962T3 - Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme - Google Patents

Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme

Info

Publication number
DK0692962T3
DK0692962T3 DK94912437T DK94912437T DK0692962T3 DK 0692962 T3 DK0692962 T3 DK 0692962T3 DK 94912437 T DK94912437 T DK 94912437T DK 94912437 T DK94912437 T DK 94912437T DK 0692962 T3 DK0692962 T3 DK 0692962T3
Authority
DK
Denmark
Prior art keywords
steroid
antagonists
receptor
prophylaxis
therapy
Prior art date
Application number
DK94912437T
Other languages
English (en)
Inventor
Rainer Denecke
Original Assignee
Altramed Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altramed Holdings Ltd filed Critical Altramed Holdings Ltd
Application granted granted Critical
Publication of DK0692962T3 publication Critical patent/DK0692962T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK94912437T 1993-04-10 1994-03-30 Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme DK0692962T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4311870A DE4311870C2 (de) 1993-04-10 1993-04-10 Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen
PCT/DE1994/000366 WO1994023708A1 (de) 1993-04-10 1994-03-30 Verwendung von steroid-antagonisten zur therapie und prophylaxe von demenz-erkrankungen

Publications (1)

Publication Number Publication Date
DK0692962T3 true DK0692962T3 (da) 1998-09-28

Family

ID=6485255

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94912437T DK0692962T3 (da) 1993-04-10 1994-03-30 Anvendelse af steroid-antagonister til terapi og profylakse af demens-sygdomme

Country Status (11)

Country Link
US (2) US6232350B1 (da)
EP (2) EP0692962B1 (da)
JP (1) JPH08508507A (da)
AT (1) ATE163543T1 (da)
AU (1) AU690110B2 (da)
CA (1) CA2160132C (da)
DE (2) DE4311870C2 (da)
DK (1) DK0692962T3 (da)
ES (1) ES2114188T3 (da)
GR (1) GR3026392T3 (da)
WO (1) WO1994023708A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552415A (en) * 1993-12-21 1996-09-03 Eli Lilly And Company Method of inhibiting Alzheimer's Disease
WO1995017095A1 (en) * 1993-12-21 1995-06-29 Eli Lilly And Company Methods for the treatment or prevention of conditions associated with amyloidogenic reptides
US6562862B1 (en) * 1994-10-20 2003-05-13 Eli Lilly And Company Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
CZ212097A3 (en) * 1995-01-20 1997-11-12 Novo Nordisk As Use of 3,4-diphenylchromans for preparing a medicament intended for treating or prophylaxis of cerebral degenerative diseases
RU2214236C2 (ru) * 1997-08-15 2003-10-20 Дьюк Юниверсити Способ профилактики или лечения эстрогензависимых заболеваний и расстройств
GB9824207D0 (en) * 1998-11-04 1998-12-30 Zeneca Ltd Neurological disorders
AR027878A1 (es) * 1999-11-05 2003-04-16 Wyeth Corp Metodos para identificar y utilizar compuestos inhibidores de amiloides
US7067550B2 (en) * 2000-11-03 2006-06-27 Massachusetts Institute Of Technology Treatments for neurotoxicity in Alzheimer's Disease
WO2005105063A1 (en) * 2004-05-03 2005-11-10 Universita' Degli Studi Di Firenze Pharmaceutical compositions containing serms for the treatment of alzheimer's disease
US7473687B2 (en) 2005-03-24 2009-01-06 Emory University Methods for the treatment of a traumatic central nervous system injury
PL2030622T3 (pl) 2005-03-24 2011-07-29 Univ Emory Wskazanie dawkowania progesteronu w leczeniu urazowego uszkodzenia mózgu

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3046719C2 (de) * 1980-12-11 1983-02-17 Klinge Pharma GmbH, 8000 München 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
US5491173A (en) * 1982-06-25 1996-02-13 Orion-Yhtyma Oy Tri-phenyl alkene derivatives and their preparation and use
US4791099A (en) * 1984-10-29 1988-12-13 Chaovanee Aroonsakul Method of treatment for central nervous system diseases such as Alzheimer's's disease
EP0263213B1 (en) * 1986-10-09 1995-09-06 The Upjohn Company C20 Through C26 amino steroids
GB9207437D0 (en) * 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites
AU674146B2 (en) * 1992-05-01 1996-12-12 British Technology Group Limited Substituted 1,1,2-triphenylbutenes and their use in the treatment and diagnosis of cancer
US5264619B1 (en) * 1993-01-15 1996-05-14 Cosmos Pharm Corp Anti-androgenic cyclo and bicyclo alkenes
US5455275A (en) * 1994-05-11 1995-10-03 Eli Lilly And Company Methods for inhibiting endometriosis and uterine fibroid disease with 1,1,2-triphenylbut-1-ene derivatives
US5470883A (en) * 1994-05-23 1995-11-28 Stromberg; Brent V. Method of treating peripheral vasoconstriction with tamoxifen citrate
IL120269A0 (en) * 1996-02-28 1997-06-10 Pfizer 1,1,2-triphenylbut-1-ene derivatives for treating Alzheimer's disease

Also Published As

Publication number Publication date
EP0797990A2 (de) 1997-10-01
ATE163543T1 (de) 1998-03-15
AU690110B2 (en) 1998-04-23
DE4311870A1 (de) 1994-10-13
EP0692962B1 (de) 1998-03-04
WO1994023708A1 (de) 1994-10-27
AU6501494A (en) 1994-11-08
DE4311870C2 (de) 1998-07-30
DE59405394D1 (de) 1998-04-09
US6232350B1 (en) 2001-05-15
EP0797990A3 (de) 1997-10-08
CA2160132C (en) 2002-01-15
US20010018434A1 (en) 2001-08-30
GR3026392T3 (en) 1998-06-30
CA2160132A1 (en) 1994-10-27
JPH08508507A (ja) 1996-09-10
ES2114188T3 (es) 1998-05-16
EP0692962A1 (de) 1996-01-24

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