DK0690845T3 - Piperazinderivater som 5-HT1A-ligander - Google Patents
Piperazinderivater som 5-HT1A-liganderInfo
- Publication number
- DK0690845T3 DK0690845T3 DK94909244T DK94909244T DK0690845T3 DK 0690845 T3 DK0690845 T3 DK 0690845T3 DK 94909244 T DK94909244 T DK 94909244T DK 94909244 T DK94909244 T DK 94909244T DK 0690845 T3 DK0690845 T3 DK 0690845T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- cycloalkyl
- lower alkyl
- date
- piperazine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939306103A GB9306103D0 (en) | 1993-03-24 | 1993-03-24 | Piperazine derivatives |
| PCT/GB1994/000539 WO1994021610A1 (en) | 1993-03-24 | 1994-03-17 | Piperazine derivatives as 5-ht1a ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0690845T3 true DK0690845T3 (da) | 1999-02-22 |
Family
ID=10732658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94909244T DK0690845T3 (da) | 1993-03-24 | 1994-03-17 | Piperazinderivater som 5-HT1A-ligander |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5693642A (da) |
| EP (1) | EP0690845B1 (da) |
| JP (1) | JPH08508031A (da) |
| AT (1) | ATE170841T1 (da) |
| AU (1) | AU6216394A (da) |
| DE (1) | DE69413213T2 (da) |
| DK (1) | DK0690845T3 (da) |
| ES (1) | ES2122245T3 (da) |
| GB (1) | GB9306103D0 (da) |
| TW (1) | TW281673B (da) |
| WO (1) | WO1994021610A1 (da) |
| ZA (1) | ZA941934B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5990114A (en) * | 1996-02-28 | 1999-11-23 | Recordati, S.A., Chemical And Pharmaceutical Company | Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence |
| US6271234B1 (en) | 1997-08-01 | 2001-08-07 | Recordati S.A., Chemical And Pharmaceutical Company | 1,4-disubstituted piperazines |
| JP2001512110A (ja) * | 1997-08-01 | 2001-08-21 | レコルダチ エッセ．ア．，ケミカル アンド ファーマシューティカル カンパニー | １，４−ジ置換ピペラジン |
| UA66370C2 (en) * | 1997-12-16 | 2004-05-17 | Lilly Co Eli | Arylpiperazines having activity to setotonin 1 receptors |
| CA2334254A1 (en) * | 1998-06-15 | 1999-12-23 | American Home Products Corporation | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents |
| US6376494B1 (en) | 1998-06-15 | 2002-04-23 | American Home Products Corporation | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents |
| US6743796B2 (en) | 2001-05-07 | 2004-06-01 | Wyeth | Piperazinyl-isatins |
| US20040072839A1 (en) * | 2002-06-14 | 2004-04-15 | Amedeo Leonardi | 1-Phenylalkylpiperazines |
| US7071197B2 (en) * | 2002-06-14 | 2006-07-04 | Recordati S.A. | N,N-disubstituted diazocycloalkanes |
| US7419980B2 (en) | 2003-10-14 | 2008-09-02 | Wyeth | Fused-aryl and heteroaryl derivatives and methods of their use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9021535D0 (en) * | 1990-10-03 | 1990-11-14 | Wyeth John & Brother Ltd | Piperazine derivatives |
| IL101722A (en) * | 1991-05-02 | 1996-05-14 | Wyeth John & Brother Ltd | History of piperazine, their preparation and pharmaceutical preparations containing them |
-
1993
- 1993-03-24 GB GB939306103A patent/GB9306103D0/en active Pending
-
1994
- 1994-03-17 EP EP94909244A patent/EP0690845B1/en not_active Expired - Lifetime
- 1994-03-17 DK DK94909244T patent/DK0690845T3/da active
- 1994-03-17 US US08/436,411 patent/US5693642A/en not_active Expired - Lifetime
- 1994-03-17 AU AU62163/94A patent/AU6216394A/en not_active Abandoned
- 1994-03-17 JP JP6520792A patent/JPH08508031A/ja active Pending
- 1994-03-17 DE DE69413213T patent/DE69413213T2/de not_active Expired - Fee Related
- 1994-03-17 AT AT94909244T patent/ATE170841T1/de not_active IP Right Cessation
- 1994-03-17 ES ES94909244T patent/ES2122245T3/es not_active Expired - Lifetime
- 1994-03-17 WO PCT/GB1994/000539 patent/WO1994021610A1/en active IP Right Grant
- 1994-03-18 ZA ZA941934A patent/ZA941934B/xx unknown
- 1994-03-23 TW TW083102520A patent/TW281673B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| ZA941934B (en) | 1995-09-18 |
| GB9306103D0 (en) | 1993-05-12 |
| ES2122245T3 (es) | 1998-12-16 |
| DE69413213T2 (de) | 1999-05-06 |
| WO1994021610A1 (en) | 1994-09-29 |
| EP0690845A1 (en) | 1996-01-10 |
| EP0690845B1 (en) | 1998-09-09 |
| ATE170841T1 (de) | 1998-09-15 |
| JPH08508031A (ja) | 1996-08-27 |
| DE69413213D1 (de) | 1998-10-15 |
| US5693642A (en) | 1997-12-02 |
| AU6216394A (en) | 1994-10-11 |
| TW281673B (da) | 1996-07-21 |
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