DK0672140T3 - Transficeret cellelinje, som udtrykker cDNA'er, der koder for human NMDA-R2A receptor subunit og isoformer af den humane NMDA-R1 receptor subunit - Google Patents

Transficeret cellelinje, som udtrykker cDNA'er, der koder for human NMDA-R2A receptor subunit og isoformer af den humane NMDA-R1 receptor subunit

Info

Publication number
DK0672140T3
DK0672140T3 DK93924747T DK93924747T DK0672140T3 DK 0672140 T3 DK0672140 T3 DK 0672140T3 DK 93924747 T DK93924747 T DK 93924747T DK 93924747 T DK93924747 T DK 93924747T DK 0672140 T3 DK0672140 T3 DK 0672140T3
Authority
DK
Denmark
Prior art keywords
receptor subunit
human nmda
nmda
cell line
subunit
Prior art date
Application number
DK93924747T
Other languages
English (en)
Inventor
Bourdelles Beatrice Le
Janice Ann Myers
Paul John Whiting
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929223769A external-priority patent/GB9223769D0/en
Priority claimed from GB939307026A external-priority patent/GB9307026D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of DK0672140T3 publication Critical patent/DK0672140T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK93924747T 1992-11-12 1993-11-11 Transficeret cellelinje, som udtrykker cDNA'er, der koder for human NMDA-R2A receptor subunit og isoformer af den humane NMDA-R1 receptor subunit DK0672140T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929223769A GB9223769D0 (en) 1992-11-12 1992-11-12 Receptor cloning
GB939307026A GB9307026D0 (en) 1993-04-02 1993-04-02 Receptor cloning
PCT/GB1993/002324 WO1994011501A1 (en) 1992-11-12 1993-11-11 cDNAs ENCODING HUMAN NMDA-22A RECEPTOR SUBUNIT AND ISOFORMS OF THE HUMAN NMDA-R1 RECEPTOR SUBUNIT, TRANSFECTED CELL LINE EXPRESSING THEM

Publications (1)

Publication Number Publication Date
DK0672140T3 true DK0672140T3 (da) 2003-03-31

Family

ID=26301962

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93924747T DK0672140T3 (da) 1992-11-12 1993-11-11 Transficeret cellelinje, som udtrykker cDNA'er, der koder for human NMDA-R2A receptor subunit og isoformer af den humane NMDA-R1 receptor subunit

Country Status (9)

Country Link
US (1) US6130058A (da)
EP (1) EP0672140B1 (da)
JP (1) JPH08503362A (da)
AT (1) ATE233319T1 (da)
AU (1) AU5429794A (da)
CA (1) CA2148599C (da)
DE (1) DE69332715T2 (da)
DK (1) DK0672140T3 (da)
WO (1) WO1994011501A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2110934A1 (en) 1992-12-11 1994-06-12 Robert L. Foldes Human cns receptors of the nmda-r1 family
JPH08509607A (ja) 1993-04-20 1996-10-15 ザ ソールク インスチチュート バイオテクノロジー／インダストリアル アソシエイツ，インコーポレイテッド ヒトｎ−メチル−ｄ−アスパラギン酸受容体サブユニット、これをコードする核酸およびその用途
EP0674003A3 (en) * 1994-03-25 1997-09-10 Allelix Biopharma Modulators of receptors in the human central nervous system.
GB9414997D0 (en) * 1994-07-26 1994-09-14 Merck Sharp & Dohme Receptor cloning
US20050037969A1 (en) * 1999-05-14 2005-02-17 Arbor Vita Corporation Molecular interactions in hematopoietic cells
JP4114029B2 (ja) * 1999-07-16 2008-07-09 株式会社セガ 画像処理装置、画像処理方法及び記録媒体
US20050064442A1 (en) * 2002-11-25 2005-03-24 Roth Richard B. Methods for identifying risk of breast cancer and treatments thereof
ATE426043T1 (de) * 2002-11-25 2009-04-15 Sequenom Inc Verfahren zur identifizierung des brustkrebsrisikos
US20050272043A1 (en) * 2003-07-24 2005-12-08 Roth Richard B Methods for identifying risk of breast cancer and treatments thereof
EP1766051A4 (en) * 2004-05-27 2007-10-10 Sequenom Inc METHOD FOR IDENTIFYING BREAST CANCER RISK AND TREATMENTS THEREOF
WO2017109709A2 (en) 2015-12-22 2017-06-29 Novartis Ag A high-throughput assay method for identifying allosteric nmda receptor modulators
CA3153217A1 (en) * 2019-09-13 2021-03-18 Euroimmun Medizinische Labordiagnostika Ag Improved detection of nmda receptor autoantibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4216321A1 (de) * 1992-05-16 1993-11-18 Basf Ag Untereinheiten von NMDA-Rezeptoren, Verfahren zu ihrer Herstellung und ihre Verwendung

Also Published As

Publication number Publication date
US6130058A (en) 2000-10-10
EP0672140B1 (en) 2003-02-26
ATE233319T1 (de) 2003-03-15
CA2148599C (en) 2004-01-20
DE69332715D1 (de) 2003-04-03
EP0672140A1 (en) 1995-09-20
DE69332715T2 (de) 2003-10-16
JPH08503362A (ja) 1996-04-16
CA2148599A1 (en) 1994-05-26
AU5429794A (en) 1994-06-08
WO1994011501A1 (en) 1994-05-26

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