DK0671388T3 - (Pyrrolidinyl)phenylcarbamater og mellemproduktforbindelser, fremgangsmåder til deres fremstilling og deres anvendelse som - Google Patents

(Pyrrolidinyl)phenylcarbamater og mellemproduktforbindelser, fremgangsmåder til deres fremstilling og deres anvendelse som

Info

Publication number
DK0671388T3
DK0671388T3 DK95103149T DK95103149T DK0671388T3 DK 0671388 T3 DK0671388 T3 DK 0671388T3 DK 95103149 T DK95103149 T DK 95103149T DK 95103149 T DK95103149 T DK 95103149T DK 0671388 T3 DK0671388 T3 DK 0671388T3
Authority
DK
Denmark
Prior art keywords
pyrrolidinyl
processes
preparation
intermediate compounds
phenylcarbamates
Prior art date
Application number
DK95103149T
Other languages
English (en)
Inventor
David Dr Wettlaufer
Peter Allen Nemoto
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Application granted granted Critical
Publication of DK0671388T3 publication Critical patent/DK0671388T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DK95103149T 1994-03-10 1995-03-06 (Pyrrolidinyl)phenylcarbamater og mellemproduktforbindelser, fremgangsmåder til deres fremstilling og deres anvendelse som DK0671388T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/208,554 US5338739A (en) 1994-03-10 1994-03-10 (Pyrrolidinyl)phenyl carbamates, compositions and use

Publications (1)

Publication Number Publication Date
DK0671388T3 true DK0671388T3 (da) 1999-02-15

Family

ID=22775020

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95103149T DK0671388T3 (da) 1994-03-10 1995-03-06 (Pyrrolidinyl)phenylcarbamater og mellemproduktforbindelser, fremgangsmåder til deres fremstilling og deres anvendelse som

Country Status (8)

Country Link
US (3) US5338739A (da)
EP (1) EP0671388B1 (da)
JP (1) JP3453211B2 (da)
AT (1) ATE167182T1 (da)
CA (1) CA2144294C (da)
DE (1) DE69502855T2 (da)
DK (1) DK0671388T3 (da)
ES (1) ES2119244T3 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19648011A1 (de) * 1996-11-20 1998-05-28 Bayer Ag Cyclische Imine
AR041885A1 (es) * 2002-11-06 2005-06-01 Smithkline Beecham Corp Compuesto de sulfonamida, composicion farmaceutica que lo comprende y su uso para preparar dicha composicion
US20060020285A1 (en) * 2004-07-22 2006-01-26 Volker Niermann Method for filtering blood in a vessel with helical elements
US20110230428A1 (en) * 2008-07-22 2011-09-22 John Wityak Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
HUE034802T2 (en) 2011-08-30 2018-02-28 Chdi Foundation Inc Kinurenin-3-monooxygenase inhibitors, pharmaceutical preparations and methods of use
SG2014011654A (en) 2011-08-30 2014-08-28 Chdi Foundation Inc Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
KR20170026633A (ko) 2014-07-17 2017-03-08 씨에이치디아이 파운데이션, 인코포레이티드 Hiv-관련 장애의 치료 방법 및 치료용 조성물
WO2017165119A1 (en) * 2016-03-21 2017-09-28 David Weinstein Methods for wound healing and scar prevention

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3149123A (en) * 1961-01-04 1964-09-15 Parke Davis & Co 1, 3-dialkyl-3-oxyphenylpyrrolidine compounds
CH484103A (de) * 1966-09-02 1970-01-15 Ciba Geigy Verfahren zur Herstellung von neuen Carbamaten
GB1178400A (en) * 1966-12-13 1970-01-21 Delalande Sa Nitrogen Substituted Amines and their process of Preparation.
US3674806A (en) * 1969-04-30 1972-07-04 Reynolds Tobacco Co R 1,3,3,4,4-pentasubstituted pyrrolidines
DE2413935A1 (de) * 1974-03-20 1975-10-16 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone
US5001142A (en) * 1989-07-19 1991-03-19 American Cyanamid Company 1-substituted-2-(3-amino-1-propynyl)pyrrolidine derivatives
US5015741A (en) * 1989-10-03 1991-05-14 Philip Morris Incorporated Nicotine analogs
ATE201669T1 (de) * 1991-04-17 2001-06-15 Upjohn Co Substituierte (s)-3-phenylpiperidin derivate, deren herstellung und deren verwendung als dopamin autorezeptor antagonisten
AU674130B2 (en) * 1991-09-26 1996-12-12 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Substituted phenserines and phenylcarbamates of (-)- eseroline, (-)-N1-noreseroline, and (-)-N1- benzylnoreseroline; as specific inhibitors of acetylcholinesterase

Also Published As

Publication number Publication date
US5591856A (en) 1997-01-07
JPH07278103A (ja) 1995-10-24
CA2144294A1 (en) 1995-09-11
EP0671388B1 (en) 1998-06-10
EP0671388A1 (en) 1995-09-13
CA2144294C (en) 2002-11-12
ATE167182T1 (de) 1998-06-15
US5405845A (en) 1995-04-11
US5338739A (en) 1994-08-16
DE69502855T2 (de) 1998-11-26
JP3453211B2 (ja) 2003-10-06
DE69502855D1 (de) 1998-07-16
ES2119244T3 (es) 1998-10-01

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