DK0670736T3 - Mærket interleukin-8 og medicinske anvendelser deraf - Google Patents

Mærket interleukin-8 og medicinske anvendelser deraf

Info

Publication number
DK0670736T3
DK0670736T3 DK93923789T DK93923789T DK0670736T3 DK 0670736 T3 DK0670736 T3 DK 0670736T3 DK 93923789 T DK93923789 T DK 93923789T DK 93923789 T DK93923789 T DK 93923789T DK 0670736 T3 DK0670736 T3 DK 0670736T3
Authority
DK
Denmark
Prior art keywords
medical uses
target site
interleukin
labeled interleukin
labeled
Prior art date
Application number
DK93923789T
Other languages
English (en)
Inventor
Leon R Lyle
Steven L Kunkel
Original Assignee
Univ Michigan Technology Man W
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan Technology Man W, Mallinckrodt Inc filed Critical Univ Michigan Technology Man W
Application granted granted Critical
Publication of DK0670736T3 publication Critical patent/DK0670736T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Radiation-Therapy Devices (AREA)
  • Nuclear Medicine (AREA)
  • Measurement Of Radiation (AREA)
DK93923789T 1992-10-05 1993-10-04 Mærket interleukin-8 og medicinske anvendelser deraf DK0670736T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/956,863 US5346686A (en) 1992-10-05 1992-10-05 Labelled interleukin-8 and medical uses thereof
PCT/US1993/009554 WO1994007535A2 (en) 1992-10-05 1993-10-04 Labelled interleukin-8 and medical uses thereof

Publications (1)

Publication Number Publication Date
DK0670736T3 true DK0670736T3 (da) 2001-11-05

Family

ID=25498784

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93923789T DK0670736T3 (da) 1992-10-05 1993-10-04 Mærket interleukin-8 og medicinske anvendelser deraf

Country Status (11)

Country Link
US (1) US5346686A (da)
EP (1) EP0670736B1 (da)
JP (1) JPH08511765A (da)
AT (1) ATE205728T1 (da)
AU (1) AU686119B2 (da)
CA (1) CA2146239C (da)
DE (1) DE69330794T2 (da)
DK (1) DK0670736T3 (da)
ES (1) ES2168098T3 (da)
PT (1) PT670736E (da)
WO (1) WO1994007535A2 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602301A (en) * 1993-11-16 1997-02-11 Indiana University Foundation Non-human mammal having a graft and methods of delivering protein to myocardial tissue
US6001606A (en) * 1994-03-08 1999-12-14 Human Genome Sciences, Inc. Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6811773B1 (en) * 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
US6391589B1 (en) 1994-08-23 2002-05-21 Human Genome Sciences, Inc. Human chemokine beta-10 mutant polypeptides
US5981230A (en) * 1994-08-23 1999-11-09 Human Genome Sciences, Inc. Polynucleotide encoding chemokine β-4
US6458349B1 (en) * 1995-06-02 2002-10-01 Human Genome Sciences, Inc. Chemokine β-4 polypeptides
US6174995B1 (en) 1994-08-23 2001-01-16 Haodong Li Human chemokines, CKβ4 and CKβ10/MCP-4
US5789539A (en) * 1994-10-26 1998-08-04 Repligen Corporation Chemokine-like proteins and methods of use
US6139832A (en) * 1995-02-08 2000-10-31 Human Genome Sciences, Inc. Leukocyte adhesion inhibitor-1 (LAI-1) Polypeptides
EP0811059A4 (en) * 1995-02-08 1998-04-01 Human Genome Sciences Inc BETA-11 HUMAN CHEMOKINE AND ALPHA-1 HUMAN CHEMOKINE
US5994292A (en) * 1995-05-31 1999-11-30 The United States Of America As Represented By The Department Of Health And Human Services Interferon-inducible protein 10 is a potent inhibitor of angiogenesis
US6410268B1 (en) * 1996-03-18 2002-06-25 Human Genome Sciences, Inc. Polynucleotides encoding chemokine alpha-3
EP0896622A4 (en) * 1996-03-19 2004-11-03 Human Genome Sciences Inc CHEMOKINE ALPHA 2
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
EP0932417B1 (en) * 1996-10-17 2003-03-05 Immunomedics, Inc. Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
US6204024B1 (en) 1997-09-12 2001-03-20 Akzo Nobel N.V. CCR5 RNA transcription based amplification assay
EP1045861B1 (en) * 1998-01-15 2009-03-04 Center For Molecular Medicine And Immunology Bispecific targeting moiety comprising an antibody to carcinoembryonic antigen (cea) and the ligand-binding region of the il13 receptor alpha subunit
US6703488B1 (en) 1998-01-15 2004-03-09 Center For Molecular Medicine And Immunology Antibody/receptor targeting moiety for enhanced delivery of armed ligand
US20030215421A1 (en) * 1999-07-21 2003-11-20 Mcdonald John R. Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders
AU2007201755B2 (en) * 1998-07-22 2007-09-20 Osprey Pharmaceuticals Usa, Inc. Conjugates for treating inflammatory disorders and associated tissue damage
EP1098664B1 (en) * 1998-07-22 2003-08-06 Osprey Pharmaceuticals Limited Conjugates for treating inflammatory disorders and associated tissue damage
US7157418B1 (en) 1998-07-22 2007-01-02 Osprey Pharmaceuticals, Ltd. Methods and compositions for treating secondary tissue damage and other inflammatory conditions and disorders
AU2003225237A1 (en) * 2002-05-01 2003-11-17 Human Genome Sciences, Inc. Antibodies that specifically bind to chemokine beta-4
EP1437145A1 (en) * 2003-01-07 2004-07-14 Schering AG Enhanced scintigraphic imaging agents for imaging of infection and inflammation
GB0905438D0 (en) * 2009-03-30 2009-05-13 Ge Healthcare Ltd Radiolabelling reagents and methods
NZ611269A (en) 2010-11-19 2015-03-27 Eisai R&D Man Co Ltd Neutralizing anti-ccl20 antibodies

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Publication number Priority date Publication date Assignee Title
US4837003A (en) * 1984-09-13 1989-06-06 Mallinckrodt, Inc. Radiolabeled antibody fragments
US4659839A (en) * 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
US5037630A (en) * 1985-01-14 1991-08-06 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
GB8525974D0 (en) * 1985-10-22 1985-11-27 Nyegaard & Co As Chemical substance
US4926869A (en) * 1986-01-16 1990-05-22 The General Hospital Corporation Method for the diagnosis and treatment of inflammation
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4965392A (en) * 1987-03-26 1990-10-23 Neorx Corporation Chelating compounds for metal-radionuclide labeled proteins
ATE106898T1 (de) * 1987-03-26 1994-06-15 Neorx Corp Metall-radionuklid-markierte proteine und glykoproteine zur diagnose und therapie.
US5120525A (en) * 1988-03-29 1992-06-09 Immunomedics, Inc. Radiolabeled antibody cytotoxic therapy of cancer
US4986979A (en) * 1989-03-14 1991-01-22 Neorx Corporation Imaging tissue sites of inflammation
CA2016235C (en) * 1989-05-09 2002-03-12 Alan J. Fischman Labeled chemotactic peptides to image focal sites of infection or inflammation
WO1991001144A1 (en) * 1989-07-20 1991-02-07 Sandoz Ltd Labeled polypeptide derivatives
EP0502897A4 (en) * 1989-11-29 1993-03-03 Brigham And Women's Hospital Endothelial-derived il-8
WO1991008231A1 (en) * 1989-11-29 1991-06-13 Brigham And Women's Hospital [Ala IL-8]77 AS A LEUKOCYTE ADHESION INHIBITOR
IE913192A1 (en) * 1990-09-12 1992-02-25 Scripps Research Inst Active site of interleukin-8: polypeptide analogs and¹antibodies
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging

Also Published As

Publication number Publication date
DE69330794T2 (de) 2002-05-23
CA2146239C (en) 2003-04-01
EP0670736B1 (en) 2001-09-19
CA2146239A1 (en) 1994-04-14
EP0670736A1 (en) 1995-09-13
ES2168098T3 (es) 2002-06-01
WO1994007535A3 (en) 1994-05-11
DE69330794D1 (de) 2001-10-25
AU686119B2 (en) 1998-02-05
WO1994007535A2 (en) 1994-04-14
PT670736E (pt) 2002-03-28
AU5353194A (en) 1994-04-26
ATE205728T1 (de) 2001-10-15
JPH08511765A (ja) 1996-12-10
US5346686A (en) 1994-09-13

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