DK0651645T3 - Fremgangsmåde og medikament til inhibering af neutrofil elastase og cathepsin G - Google Patents

Fremgangsmåde og medikament til inhibering af neutrofil elastase og cathepsin G

Info

Publication number
DK0651645T3
DK0651645T3 DK93918338T DK93918338T DK0651645T3 DK 0651645 T3 DK0651645 T3 DK 0651645T3 DK 93918338 T DK93918338 T DK 93918338T DK 93918338 T DK93918338 T DK 93918338T DK 0651645 T3 DK0651645 T3 DK 0651645T3
Authority
DK
Denmark
Prior art keywords
cathepsin
desulfated heparin
neutrophil elastase
medicament
drug
Prior art date
Application number
DK93918338T
Other languages
English (en)
Inventor
Thomas P Kennedy
Original Assignee
Thomas P Kennedy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas P Kennedy filed Critical Thomas P Kennedy
Application granted granted Critical
Publication of DK0651645T3 publication Critical patent/DK0651645T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Polymers & Plastics (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • External Artificial Organs (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
DK93918338T 1992-07-24 1993-07-23 Fremgangsmåde og medikament til inhibering af neutrofil elastase og cathepsin G DK0651645T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91930992A 1992-07-24 1992-07-24
PCT/US1993/006933 WO1994002107A2 (en) 1992-07-24 1993-07-23 Method and medicament for inhibiting neutrophil elastase and cathepsin g

Publications (1)

Publication Number Publication Date
DK0651645T3 true DK0651645T3 (da) 2002-06-10

Family

ID=25441870

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93918338T DK0651645T3 (da) 1992-07-24 1993-07-23 Fremgangsmåde og medikament til inhibering af neutrofil elastase og cathepsin G
DK01115601T DK1164145T3 (da) 1992-07-24 1993-07-23 Ikke-antikoagulant desulfateret heparin som medikament

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01115601T DK1164145T3 (da) 1992-07-24 1993-07-23 Ikke-antikoagulant desulfateret heparin som medikament

Country Status (10)

Country Link
EP (2) EP1164145B1 (da)
JP (1) JPH08511764A (da)
AT (2) ATE380047T1 (da)
AU (1) AU688272B2 (da)
CA (1) CA2140890C (da)
DE (2) DE69334190T2 (da)
DK (2) DK0651645T3 (da)
ES (2) ES2173893T3 (da)
PT (1) PT1164145E (da)
WO (1) WO1994002107A2 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696100A (en) * 1992-12-22 1997-12-09 Glycomed Incorporated Method for controlling O-desulfation of heparin and compositions produced thereby
AU6246394A (en) * 1993-02-22 1994-09-14 Cavalier Pharmaceuticals, Inc. Use of heparin to inhibit interleukin-8
US6242414B1 (en) 1995-06-07 2001-06-05 Chiron Corporation Regulation of cytokine synthesis and release
WO2002032406A2 (en) * 2000-10-18 2002-04-25 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
US7468358B2 (en) * 2004-06-16 2008-12-23 Paringenix, Inc. Method and medicament for sulfated polysaccharide treatment of heparin-induced thrombocytopenia (HIT) syndrome

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584606A1 (fr) * 1985-07-12 1987-01-16 Dropic Utilisation de poly- et oligosaccharides pour l'obtention de medicaments actifs dans les pathologies du tissu conjonctif
US5262403A (en) * 1986-03-10 1993-11-16 Board Of Regents, The University Of Texas System Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness of metastatic profusion-II
AU7852687A (en) * 1986-08-21 1988-03-08 University Of Texas System, The Glycosaminoglycan derivatives and their use as inhibitors of tumor invasiveness or metastatic profusion
IT1254216B (it) * 1992-02-25 1995-09-14 Opocrin Spa Derivati polisaccaridici di eparina, eparan solfato, loro frazioni e frammenti, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
ES2173893T3 (es) 2002-11-01
ES2295087T3 (es) 2008-04-16
PT1164145E (pt) 2008-03-17
WO1994002107A2 (en) 1994-02-03
DE69334190T2 (de) 2008-11-27
DE69334190D1 (de) 2008-01-17
EP1164145A3 (en) 2002-01-30
JPH08511764A (ja) 1996-12-10
AU4782493A (en) 1994-02-14
ATE213636T1 (de) 2002-03-15
DK1164145T3 (da) 2008-04-14
ATE380047T1 (de) 2007-12-15
EP0651645A1 (en) 1995-05-10
EP1164145B1 (en) 2007-12-05
CA2140890A1 (en) 1994-02-03
EP1164145A2 (en) 2001-12-19
WO1994002107A3 (en) 1994-05-11
CA2140890C (en) 2003-10-07
DE69331633T2 (de) 2002-10-31
EP0651645B1 (en) 2002-02-27
DE69331633D1 (de) 2002-04-04
AU688272B2 (en) 1998-03-12

Similar Documents

Publication Publication Date Title
DK0571602T3 (da) Dimer af molekylær variant af apolipoprotein og fremgangsmåder til fremstilling deraf
ES2137948T3 (es) Sistema avanzado de administracion de medicamentos y metodo de tratamiento de trastornos psiquiatricos, neurologicos y otros con carbamacepina.
RU93054168A (ru) Димер молекулярного варианта аро-липопротеина, способ его получения, фармацевтическая композиция на его основе
DK0532862T3 (da) Anvendelse af rapamycin til fremstilling af et lægemiddel til behandling af øjeninflammation
BR0213293A (pt) Uso de tfpi ou de um análogo de tfpi no tratamento de septicemia
ATE240344T1 (de) Nor-pregnane zur induzierung hypothalamischer effekte
DK0558468T3 (da) Lægemiddel til inhibering af nitrogenoxiddannelse
DK0651645T3 (da) Fremgangsmåde og medikament til inhibering af neutrofil elastase og cathepsin G
ES2180564T3 (es) 2-fenil-3-azoilbenzotiofenos para aumentar la expresion de trombomodulina.
DK0498144T3 (da) Anvendelse af acetyl-L-carnitin ved terapeutisk behandling af coma
PT666739E (pt) Solucao intravenosa que diminui a perda de proteina no corpo.
TW325997B (en) Pharmaceutical composition for preventing and treating retinal diseases
KR960705578A (ko) 경증 질환을 가진 b형 간염 보균자의 치료방법(method for treating hepatitis b carriers with minimal disease)
GEP20012511B (en) Method for Lowering Level of Lipoproteins (a) in Serum or Plasma of Mammals, Method for Treatment of Peripheral Vascular Diseases or Restenosis
CA2159485A1 (en) Anti-oxydant alkylaryl polyether alcohol polymers
CA2065889A1 (en) Increasing the choroidal blood flow
Stürzebecher et al. Synthetic Low-Molecular Weight Thrombin Inhibitors: The Ideal Antithrombotic Drug? an Introduction
SE9301324D0 (sv) New method of treatment
FR2701213B3 (fr) Canule d'injection pour traitements médicaux.
KR960703608A (ko) 호중구 매개된 결합조직 손상을 방지하는 방법(Method of preventing neutrophil mediated connective tissue damage)
TH19834EX (th) วิธีการรักษาเซฟติคซอคโดยใช้ไธโมซิน-อัลฟา1
RU99111088A (ru) Способ лечения инфекции streptococcus pneumoniae
RU96112181A (ru) Лечение ревматоидного артрита
KR930700109A (ko) 신경 질환 치료용 4,4'-[9h-플루오렌-9-일리덴비스(메틸렌)]-비스피리미딘