DK0643767T3 - Osteogene peptider - Google Patents

Osteogene peptider

Info

Publication number
DK0643767T3
DK0643767T3 DK91919612T DK91919612T DK0643767T3 DK 0643767 T3 DK0643767 T3 DK 0643767T3 DK 91919612 T DK91919612 T DK 91919612T DK 91919612 T DK91919612 T DK 91919612T DK 0643767 T3 DK0643767 T3 DK 0643767T3
Authority
DK
Denmark
Prior art keywords
osteogenic
methods
proteins
polypeptide chains
osteogenic devices
Prior art date
Application number
DK91919612T
Other languages
Danish (da)
English (en)
Inventor
Hermann Oppermann
Engin Ozkaynak
David C Reuger
Thangavel Kuberasampath
Original Assignee
Stryker Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stryker Corp filed Critical Stryker Corp
Application granted granted Critical
Publication of DK0643767T3 publication Critical patent/DK0643767T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK91919612T 1990-10-18 1991-10-18 Osteogene peptider DK0643767T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59954390A 1990-10-18 1990-10-18
PCT/US1991/007635 WO1992007073A1 (en) 1990-10-18 1991-10-18 Osteogenic peptides

Publications (1)

Publication Number Publication Date
DK0643767T3 true DK0643767T3 (da) 1999-04-26

Family

ID=24400058

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91919612T DK0643767T3 (da) 1990-10-18 1991-10-18 Osteogene peptider

Country Status (9)

Country Link
EP (1) EP0643767B1 (ja)
JP (2) JPH07500487A (ja)
AT (1) ATE168719T1 (ja)
AU (1) AU663689B2 (ja)
CA (1) CA2094027C (ja)
DE (1) DE69129865T2 (ja)
DK (1) DK0643767T3 (ja)
ES (1) ES2120964T3 (ja)
WO (1) WO1992007073A1 (ja)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7378392B1 (en) 1990-05-16 2008-05-27 Genetics Institute, Llc Bone and cartilage inductive proteins
US5688678A (en) * 1990-05-16 1997-11-18 Genetics Institute, Inc. DNA encoding and methods for producing BMP-8 proteins
WO1991018098A1 (en) * 1990-05-16 1991-11-28 Genetics Institute, Inc. Bone and cartilage inductive proteins
US6090776A (en) * 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US5652118A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. Nucleic acid encoding a novel morphogenic protein, OP-3
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
US6395883B1 (en) 1991-03-11 2002-05-28 Curis, Inc. Soluble morphogenic protein complex compositions of matter
US6194376B1 (en) 1991-03-11 2001-02-27 Creative Biomolecules, Inc. Method for modulating inflammatory response comprising administering morphogen
US5739107A (en) * 1991-03-11 1998-04-14 Creative Biomolecules, Inc. Morphogen treatment of gastrointestinal ulcers
US6287816B1 (en) 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
JP3485917B2 (ja) * 1991-06-25 2004-01-13 ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー Ｂｍｐ−９蛋白
CA2116562C (en) * 1991-08-30 1999-04-13 Thangavel Kuberasampath Morphogen-induced modulation of inflammatory response
AU678380B2 (en) * 1992-07-31 1997-05-29 Stryker Corporation Morphogenic protein soluble complex and composition thereof
WO1994015949A1 (en) * 1993-01-12 1994-07-21 Johns Hopkins University School Of Medicine Growth differentiation factor-5
AU688779B2 (en) 1993-07-09 1998-03-19 Johns Hopkins University School Of Medicine, The Growth differentiation factor-7
US6040431A (en) * 1995-06-07 2000-03-21 Stryker Corporation Single chain analogs of the TGF-β superfamily (morphons)
EP0845006A2 (en) * 1995-08-14 1998-06-03 Creative Biomolecules, Inc. Binding of osteogenic protein-i (op-1) and analogs thereof to the cell surface receptor alk-1 and analogs thereof
WO1997026277A2 (en) * 1996-01-22 1997-07-24 Creative Biomolecules, Inc. Morphogen analogs and methods for producing them
ES2201287T5 (es) 1996-03-22 2007-10-16 Curis, Inc. Metodo para mejorar la recuperacion funcional de la coordinacion motora, del habla o la percepcion sensorial tras una isquemia o trauma del sistema nervioso central.
US6034062A (en) * 1997-03-13 2000-03-07 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-9 compositions and their uses
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
AU2001241166A1 (en) * 2000-03-16 2001-09-24 Kyowa Hakko Kogyo Co. Ltd. Kidney repairing factor
ATE303169T1 (de) 2001-11-19 2005-09-15 Scil Technology Gmbh Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften
DE60304584T2 (de) 2002-09-10 2007-04-26 Scil Technology Gmbh Unter verringerter sauerstoffkonzentration mit einem osteoinduktiven protein beschichtetes metallimplantat
CA2558395C (en) 2004-03-10 2011-11-29 Scil Technology Gmbh Coated implants, their manufacturing and use thereof
JP2009515529A (ja) * 2005-11-14 2009-04-16 メリアル リミテッド 腎不全のための遺伝子療法
WO2023272658A1 (zh) * 2021-06-30 2023-01-05 北京泽勤生物医药有限公司 增强成骨细胞活性的多肽及其在治疗骨科疾病中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE01201555T1 (de) * 1988-04-08 2004-07-08 Stryker Corp., Kalamazoo Biosynthetische osteogene Proteine und solche enthaltende osteogene Einrichtungen
DE69031939T2 (de) * 1989-03-28 1998-09-10 Genetics Institute, Inc., Cambridge, Mass. Osteoinduktive zusammensetzungen

Also Published As

Publication number Publication date
DE69129865D1 (de) 1998-08-27
EP0643767B1 (en) 1998-07-22
ATE168719T1 (de) 1998-08-15
DE69129865T2 (de) 1999-03-04
WO1992007073A1 (en) 1992-04-30
CA2094027A1 (en) 1992-04-19
ES2120964T3 (es) 1998-11-16
AU663689B2 (en) 1995-10-19
JPH07500487A (ja) 1995-01-19
CA2094027C (en) 2001-12-25
AU8900091A (en) 1992-05-20
EP0643767A1 (en) 1995-03-22
JPH11262395A (ja) 1999-09-28

Similar Documents

Publication Publication Date Title
ES2120964T3 (es) Peptidos osteogenicos.
ATE231523T1 (de) Osteogene vorrichtungen
DK0448704T3 (da) Osteogene anordninger
DE69939330D1 (de) Wachstumsfaktor-homologe zvegf-3
DE3881023D1 (de) Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
NO992158L (no) Nukleinsyre- og aminosyresekvenser forbundet med Heliobacter Pylori og vaksinepreparater av disse.
ATE166231T1 (de) Produktion und verwendung von antihelmintischen substanzen und schützenden immunogenen
DE59109235D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
DE3873273D1 (de) Verfahren zur selektiven spaltung von fusionsproteinen.
ATE123056T1 (de) Ancrod-proteine, ihre herstellung und verwendung.
DK0779297T3 (da) Antigene peptider med glycinsubstitutioner
DE59106997D1 (de) Ancrod ähnliche proteine, ihre herstellung und verwendung.
DE3876240D1 (ja)
DE60138885D1 (de) Polypeptide mit aktivität der stimulierung von neutrophilen