DK0643767T3 - Osteogene peptider - Google Patents

Osteogene peptider

Info

Publication number
DK0643767T3
DK0643767T3 DK91919612T DK91919612T DK0643767T3 DK 0643767 T3 DK0643767 T3 DK 0643767T3 DK 91919612 T DK91919612 T DK 91919612T DK 91919612 T DK91919612 T DK 91919612T DK 0643767 T3 DK0643767 T3 DK 0643767T3
Authority
DK
Denmark
Prior art keywords
osteogenic
methods
proteins
polypeptide chains
osteogenic devices
Prior art date
Application number
DK91919612T
Other languages
Danish (da)
English (en)
Inventor
Hermann Oppermann
Engin Ozkaynak
David C Reuger
Thangavel Kuberasampath
Original Assignee
Stryker Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stryker Corp filed Critical Stryker Corp
Application granted granted Critical
Publication of DK0643767T3 publication Critical patent/DK0643767T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/51Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK91919612T 1990-10-18 1991-10-18 Osteogene peptider DK0643767T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59954390A 1990-10-18 1990-10-18
PCT/US1991/007635 WO1992007073A1 (fr) 1990-10-18 1991-10-18 Peptides osteogeniques

Publications (1)

Publication Number Publication Date
DK0643767T3 true DK0643767T3 (da) 1999-04-26

Family

ID=24400058

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91919612T DK0643767T3 (da) 1990-10-18 1991-10-18 Osteogene peptider

Country Status (9)

Country Link
EP (1) EP0643767B1 (fr)
JP (2) JPH07500487A (fr)
AT (1) ATE168719T1 (fr)
AU (1) AU663689B2 (fr)
CA (1) CA2094027C (fr)
DE (1) DE69129865T2 (fr)
DK (1) DK0643767T3 (fr)
ES (1) ES2120964T3 (fr)
WO (1) WO1992007073A1 (fr)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7378392B1 (en) 1990-05-16 2008-05-27 Genetics Institute, Llc Bone and cartilage inductive proteins
CA2082941A1 (fr) * 1990-05-16 1991-11-17 Rodney M. Hewick Proteines participant a l'induction d'os et de cartilage
US5688678A (en) * 1990-05-16 1997-11-18 Genetics Institute, Inc. DNA encoding and methods for producing BMP-8 proteins
US6090776A (en) * 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US6395883B1 (en) 1991-03-11 2002-05-28 Curis, Inc. Soluble morphogenic protein complex compositions of matter
US5739107A (en) * 1991-03-11 1998-04-14 Creative Biomolecules, Inc. Morphogen treatment of gastrointestinal ulcers
US5652118A (en) * 1991-03-11 1997-07-29 Creative Biomolecules, Inc. Nucleic acid encoding a novel morphogenic protein, OP-3
US6194376B1 (en) 1991-03-11 2001-02-27 Creative Biomolecules, Inc. Method for modulating inflammatory response comprising administering morphogen
US6077823A (en) * 1991-03-11 2000-06-20 Creative Biomolecules, Inc. Method for reducing tissue damage associated with ischemia-reperfusion or hypoxia injury
EP0592562B1 (fr) * 1991-06-25 1999-01-07 Genetics Institute, Inc. Compositions bmp-9
US6287816B1 (en) * 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
JP3693338B2 (ja) * 1991-08-30 2005-09-07 キュリス インコーポレイテッド 組織形成因子誘導による炎症反応の調節
ATE287949T1 (de) * 1992-07-31 2005-02-15 Stryker Corp Löslicher komplex morphogener proteine und zusammensetzungen davon
WO1994015949A1 (fr) * 1993-01-12 1994-07-21 Johns Hopkins University School Of Medicine Facteur-5 de croissance et de differentiation
US5986058A (en) 1993-07-09 1999-11-16 The Johns Hopkins University School Of Medicine Polynucleotide encoding growth differentiation factor-7 and protein encoded thereby
US6040431A (en) * 1995-06-07 2000-03-21 Stryker Corporation Single chain analogs of the TGF-β superfamily (morphons)
CA2229557A1 (fr) * 1995-08-14 1997-02-27 Creative Biomolecules, Inc. Liaison de la proteine oestrogene 1 (op-1) et de ses analogues avec le recepteur alk-1 de surface de cellule et ses analogues
EP0876401B1 (fr) * 1996-01-22 2007-06-13 Curis, Inc. Procedes de production d'analogues morphogenes op-1
DE69740089D1 (de) 1996-03-22 2011-02-10 Stryker Corp Verfahren zur verbesserten funktionellen Erholung der motorischen Koordiination, der Sprache oder der Sinneswahrnehmung nach Trauma oder Ischämie des ZNS
US6034062A (en) * 1997-03-13 2000-03-07 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-9 compositions and their uses
DE19906096A1 (de) 1999-02-13 2000-08-17 Walter Sebald Protein mit einem Heparin-bindenden Epitop
WO2001068817A1 (fr) * 2000-03-16 2001-09-20 Kyowa Hakko Kogyo Co., Ltd. Facteur de reparation du rein
ATE303169T1 (de) 2001-11-19 2005-09-15 Scil Technology Gmbh Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften
US7763270B2 (en) 2002-09-10 2010-07-27 Scil Technology Gmbh Metal implant coated under reduced oxygen concentration with osteoinductive protein
ES2350939T3 (es) 2004-03-10 2011-01-28 Scil Technology Gmbh Implantes recubiertos, su fabricación y uso de los mismos.
EP3147296A1 (fr) * 2005-11-14 2017-03-29 Merial, Inc. Thérapie génique pour traiter l'insuffisance rénale
WO2023272658A1 (fr) * 2021-06-30 2023-01-05 北京泽勤生物医药有限公司 Polypeptide pour améliorer l'activité des ostéoblastes, et son utilisation dans le traitement d'une maladie orthopédique

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68929472T2 (de) * 1988-04-08 2004-05-13 Stryker Corp., Kalamazoo Biosynthetische knochenbildende Proteine, und sie enthaltende knochenbildende Vorrichtungen
ATE162223T1 (de) * 1989-03-28 1998-01-15 Genetics Inst Osteoinduktive zusammensetzungen

Also Published As

Publication number Publication date
DE69129865T2 (de) 1999-03-04
DE69129865D1 (de) 1998-08-27
AU663689B2 (en) 1995-10-19
WO1992007073A1 (fr) 1992-04-30
ATE168719T1 (de) 1998-08-15
CA2094027A1 (fr) 1992-04-19
AU8900091A (en) 1992-05-20
JPH11262395A (ja) 1999-09-28
ES2120964T3 (es) 1998-11-16
EP0643767A1 (fr) 1995-03-22
EP0643767B1 (fr) 1998-07-22
JPH07500487A (ja) 1995-01-19
CA2094027C (fr) 2001-12-25

Similar Documents

Publication Publication Date Title
DK0643767T3 (da) Osteogene peptider
DE68929453D1 (de) Osteogene Vorrichtungen
DE69032424D1 (de) Osteogene vorrichtungen
DE69939330D1 (de) Wachstumsfaktor-homologe zvegf-3
DE3881023D1 (de) Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
NO992158L (no) Nukleinsyre- og aminosyresekvenser forbundet med Heliobacter Pylori og vaksinepreparater av disse.
DE69032323T2 (de) Produktion und verwendung von antihelmintischen substanzen und schützenden immunogenen
DE59109235D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
DE3873273D1 (de) Verfahren zur selektiven spaltung von fusionsproteinen.
ATE123056T1 (de) Ancrod-proteine, ihre herstellung und verwendung.
DK0779297T3 (da) Antigene peptider med glycinsubstitutioner
ATE130872T1 (de) Ancrod ähnliche proteine, ihre herstellung und verwendung.
DE3876240D1 (fr)
DE60138885D1 (de) Polypeptide mit aktivität der stimulierung von neutrophilen