DK0641216T3 - Farmaceutisk præparat indeholdende IL-6 - Google Patents

Farmaceutisk præparat indeholdende IL-6

Info

Publication number
DK0641216T3
DK0641216T3 DK93909917.2T DK93909917T DK0641216T3 DK 0641216 T3 DK0641216 T3 DK 0641216T3 DK 93909917 T DK93909917 T DK 93909917T DK 0641216 T3 DK0641216 T3 DK 0641216T3
Authority
DK
Denmark
Prior art keywords
pct
date nov
pharmaceutical preparation
preparation containing
sec
Prior art date
Application number
DK93909917.2T
Other languages
Danish (da)
English (en)
Inventor
Fabrizio Samaritani
Filippo Rendina
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of DK0641216T3 publication Critical patent/DK0641216T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93909917.2T 1992-05-11 1993-05-07 Farmaceutisk præparat indeholdende IL-6 DK0641216T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920349A IT1254359B (it) 1992-05-11 1992-05-11 Composizioni farmaceutiche contenenti il-6

Publications (1)

Publication Number Publication Date
DK0641216T3 true DK0641216T3 (da) 1998-01-26

Family

ID=11400994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93909917.2T DK0641216T3 (da) 1992-05-11 1993-05-07 Farmaceutisk præparat indeholdende IL-6

Country Status (12)

Country Link
US (1) US5635176A (fr)
EP (1) EP0641216B1 (fr)
JP (1) JP3714951B2 (fr)
AT (1) ATE157256T1 (fr)
AU (1) AU676833B2 (fr)
CA (1) CA2117761C (fr)
DE (1) DE69313444T2 (fr)
DK (1) DK0641216T3 (fr)
ES (1) ES2105257T3 (fr)
GR (1) GR3024708T3 (fr)
IT (1) IT1254359B (fr)
WO (1) WO1993023065A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU695129B2 (en) * 1995-02-06 1998-08-06 Genetics Institute, Llc Formulations for IL-12
GB9508691D0 (en) * 1995-04-28 1995-06-14 Pafra Ltd Stable compositions
US6267958B1 (en) 1995-07-27 2001-07-31 Genentech, Inc. Protein formulation
DE19539574A1 (de) 1995-10-25 1997-04-30 Boehringer Mannheim Gmbh Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren
US5770700A (en) * 1996-01-25 1998-06-23 Genetics Institute, Inc. Liquid factor IX formulations
US6632648B1 (en) * 1996-05-14 2003-10-14 Elan Drug Delivery Limited Methods of terminal sterilization of fibrinogen
US7141393B2 (en) * 1996-12-26 2006-11-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18-receptor proteins
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6433760B1 (en) 1999-01-14 2002-08-13 University Of Central Florida Head mounted display with eyetracking capability
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
EP1356809A4 (fr) * 2000-12-28 2008-05-14 Takeda Pharmaceutical Preparations a liberation soutenue
MXPA04005865A (es) 2001-12-19 2004-09-13 Nektar Therapeutics Suministro de aminoglucosidos a los pulmones.
SI1475101T1 (sl) * 2002-02-14 2011-03-31 Chugai Pharmaceutical Co Ltd Farmacevtski proizvodi iz raztopine, ki vsebuje protitelo

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457916A (en) * 1982-08-31 1984-07-03 Asahi Kasei Kogyo Kabushiki Kaisha Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same
US4891319A (en) * 1985-07-09 1990-01-02 Quadrant Bioresources Limited Protection of proteins and the like
DE3650715T2 (de) * 1985-10-14 1999-06-24 Yeda Research And Development Co., Ltd., Rehovot Verwendung von menschlichem Interferon-Beta 2A für die Herstellung von Medikamenten
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
DE3621828A1 (de) * 1986-06-28 1988-01-14 Biotest Pharma Gmbh Stabilisierung eines fuer therapeutische zwecke, insbesondere beim menschen, bestimmten interleukin-2-praeparates sowie dieses praeparat enthaltende stabilisierte waessrige loesung oder feststoff
US5078997A (en) * 1988-07-13 1992-01-07 Cetus Corporation Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
US5104651A (en) * 1988-12-16 1992-04-14 Amgen Inc. Stabilized hydrophobic protein formulations of g-csf
JP2805224B2 (ja) * 1989-01-13 1998-09-30 味の素株式会社 血小板減少症治療剤
JPH0327320A (ja) * 1989-06-26 1991-02-05 Ajinomoto Co Inc ヒトｂ細胞分化因子医薬組成物
JPH05963A (ja) * 1990-04-13 1993-01-08 Toray Ind Inc ポリペプチド類組成物
US5416071A (en) * 1991-03-12 1995-05-16 Takeda Chemical Industries, Ltd. Water-soluble composition for sustained-release containing epo and hyaluronic acid
EP0560998A4 (en) * 1991-10-09 1993-12-01 Toray Industries, Inc. Medicine for preventing and treating bleeding tendency
JP3027320U (ja) 1996-01-27 1996-08-09 三千男 高橋 野球グラブの装着補強具

Also Published As

Publication number Publication date
JP3714951B2 (ja) 2005-11-09
AU4065393A (en) 1993-12-13
GR3024708T3 (en) 1997-12-31
US5635176A (en) 1997-06-03
JPH08502722A (ja) 1996-03-26
CA2117761C (fr) 2005-10-04
IT1254359B (it) 1995-09-14
CA2117761A1 (fr) 1993-11-25
EP0641216A1 (fr) 1995-03-08
EP0641216B1 (fr) 1997-08-27
ES2105257T3 (es) 1997-10-16
ITRM920349A1 (it) 1993-11-11
ATE157256T1 (de) 1997-09-15
WO1993023065A1 (fr) 1993-11-25
DE69313444T2 (de) 1998-01-02
AU676833B2 (en) 1997-03-27
ITRM920349A0 (it) 1992-05-11
DE69313444D1 (de) 1997-10-02

Similar Documents

Publication Publication Date Title
MY128629A (en) Stabilized interleukin 2
DK0641216T3 (da) Farmaceutisk præparat indeholdende IL-6
KR950703987A (ko) G-csf의 안정한 동결건조된 약제학적 제제(stable lyophilized pharma ceutical preparations g-csf)
AU590618B2 (en) Stable formulation of biologically active proteins for parenteral injection
ATE140969T1 (de) Il-3 mit zusätzlichen cysteinresten und chemische modifikationen davon
NO952321L (no) Polypeptid, samt anti-HIV-preparat fremstilt fra dette
ITRM910952A1 (it) Composizioni farmaceutiche contenenti gonadotropine.
IL126463A0 (en) A pharmaceutical formulation containing growth hormone an amino acid and a non-ionic detergent
FI910286A0 (fi) Analoger av humant insulin och preparat innehaollande dessa.
SE9301172D0 (sv) Foerfarande foer framstaellning av en peptidalkohol
DK0679092T3 (da) Cytokindæmpende midler
ATE148630T1 (de) Stabilisierte derivate von vitamin d2 und d3 enthaltende pharmazeutische zusammensetzungen
HU9401831D0 (en) Stabilized pharmaceutical formulations comprising growth hormone and asparagine
DE69715414D1 (de) Stabilisierte pharmazeutische zusammensetzung von bdnf
ATE184798T1 (de) Hgh enthaltende pharmazeutische zubereitungen
IT1272252B (it) Formulazioni liquide di interferone beta
ATE151636T1 (de) Diphosphonsäuren und deren salze enthaltende arzneimittel
UA74388C2 (uk) Фармацевтичні композиції тизоксаніду і нітазоксаніду
ATE126063T1 (de) Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen.
ATE189262T1 (de) Interferon-alpha/beta bindendes protein, seine herstellung und seine enthaltende pharmazeutische zusammensetzungen
EP0351876A3 (fr) Composition pour augmenter l'effet de vaccination
ES2073063T3 (es) Formulaciones galenicas acuosas de eritropoyetina y su uso.
JPS6479125A (en) Antitumor agent
SE8703183L (sv) Nya galeniska beredningar