DK0638554T3 - Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat - Google Patents
Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivatInfo
- Publication number
- DK0638554T3 DK0638554T3 DK94202304.5T DK94202304T DK0638554T3 DK 0638554 T3 DK0638554 T3 DK 0638554T3 DK 94202304 T DK94202304 T DK 94202304T DK 0638554 T3 DK0638554 T3 DK 0638554T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- piperidinyl
- phenyl
- amide derivative
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939316863A GB9316863D0 (en) | 1993-08-13 | 1993-08-13 | Chemical process |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0638554T3 true DK0638554T3 (da) | 1998-02-09 |
Family
ID=10740452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94202304.5T DK0638554T3 (da) | 1993-08-13 | 1994-08-11 | Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat |
Country Status (10)
Country | Link |
---|---|
US (1) | US5599938A (da) |
EP (1) | EP0638554B1 (da) |
JP (1) | JP3429370B2 (da) |
AT (1) | ATE159519T1 (da) |
DE (1) | DE69406382T2 (da) |
DK (1) | DK0638554T3 (da) |
ES (1) | ES2109595T3 (da) |
GB (1) | GB9316863D0 (da) |
GR (1) | GR3025213T3 (da) |
SG (1) | SG52444A1 (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5866591A (en) * | 1996-09-11 | 1999-02-02 | Glaxo Wellcome Inc. | Stable formulations of remifentanil |
CN101312949A (zh) * | 2005-11-17 | 2008-11-26 | 马林克罗特公司 | 合成瑞芬太尼的方法 |
CN101374812A (zh) * | 2006-01-24 | 2009-02-25 | 马林克罗特公司 | 合成瑞芬太尼的方法 |
SI3199523T1 (sl) | 2016-01-29 | 2018-12-31 | Bioka S.R.O. | Nov postopek za pridobivanje n-fenil-n-(4-piperinidil)amidnih derivatov kot sta remifentanil in karfentanil |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179569A (en) * | 1975-03-14 | 1979-12-18 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl)-N-phenylamides |
US3998834A (en) * | 1975-03-14 | 1976-12-21 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl)-n-phenylamides and -carbamates |
US4584303A (en) * | 1984-04-09 | 1986-04-22 | The Boc Group, Inc. | N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds |
US5019583A (en) * | 1989-02-15 | 1991-05-28 | Glaxo Inc. | N-phenyl-N-(4-piperidinyl)amides useful as analgesics |
-
1993
- 1993-08-13 GB GB939316863A patent/GB9316863D0/en active Pending
-
1994
- 1994-08-09 US US08/287,910 patent/US5599938A/en not_active Expired - Lifetime
- 1994-08-11 JP JP18867594A patent/JP3429370B2/ja not_active Expired - Lifetime
- 1994-08-11 EP EP94202304A patent/EP0638554B1/en not_active Expired - Lifetime
- 1994-08-11 DK DK94202304.5T patent/DK0638554T3/da active
- 1994-08-11 SG SG1996004614A patent/SG52444A1/en unknown
- 1994-08-11 AT AT94202304T patent/ATE159519T1/de active
- 1994-08-11 DE DE69406382T patent/DE69406382T2/de not_active Expired - Lifetime
- 1994-08-11 ES ES94202304T patent/ES2109595T3/es not_active Expired - Lifetime
-
1997
- 1997-10-29 GR GR970402850T patent/GR3025213T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0638554A1 (en) | 1995-02-15 |
DE69406382D1 (de) | 1997-11-27 |
ATE159519T1 (de) | 1997-11-15 |
DE69406382T2 (de) | 1998-02-26 |
JP3429370B2 (ja) | 2003-07-22 |
SG52444A1 (en) | 1998-09-28 |
JPH07165713A (ja) | 1995-06-27 |
EP0638554B1 (en) | 1997-10-22 |
GR3025213T3 (en) | 1998-02-27 |
US5599938A (en) | 1997-02-04 |
GB9316863D0 (en) | 1993-09-29 |
ES2109595T3 (es) | 1998-01-16 |
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