DK0638554T3 - Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat - Google Patents

Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat

Info

Publication number
DK0638554T3
DK0638554T3 DK94202304.5T DK94202304T DK0638554T3 DK 0638554 T3 DK0638554 T3 DK 0638554T3 DK 94202304 T DK94202304 T DK 94202304T DK 0638554 T3 DK0638554 T3 DK 0638554T3
Authority
DK
Denmark
Prior art keywords
preparation
piperidinyl
phenyl
amide derivative
chem
Prior art date
Application number
DK94202304.5T
Other languages
English (en)
Inventor
William David Stuart Latham
Michael David Goodyear
Andrew Jonathan Whitehead
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DK0638554T3 publication Critical patent/DK0638554T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DK94202304.5T 1993-08-13 1994-08-11 Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat DK0638554T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939316863A GB9316863D0 (en) 1993-08-13 1993-08-13 Chemical process

Publications (1)

Publication Number Publication Date
DK0638554T3 true DK0638554T3 (da) 1998-02-09

Family

ID=10740452

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94202304.5T DK0638554T3 (da) 1993-08-13 1994-08-11 Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat

Country Status (10)

Country Link
US (1) US5599938A (da)
EP (1) EP0638554B1 (da)
JP (1) JP3429370B2 (da)
AT (1) ATE159519T1 (da)
DE (1) DE69406382T2 (da)
DK (1) DK0638554T3 (da)
ES (1) ES2109595T3 (da)
GB (1) GB9316863D0 (da)
GR (1) GR3025213T3 (da)
SG (1) SG52444A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866591A (en) * 1996-09-11 1999-02-02 Glaxo Wellcome Inc. Stable formulations of remifentanil
CN101312949A (zh) * 2005-11-17 2008-11-26 马林克罗特公司 合成瑞芬太尼的方法
CN101374812A (zh) * 2006-01-24 2009-02-25 马林克罗特公司 合成瑞芬太尼的方法
SI3199523T1 (sl) 2016-01-29 2018-12-31 Bioka S.R.O. Nov postopek za pridobivanje n-fenil-n-(4-piperinidil)amidnih derivatov kot sta remifentanil in karfentanil

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179569A (en) * 1975-03-14 1979-12-18 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-N-phenylamides
US3998834A (en) * 1975-03-14 1976-12-21 Janssen Pharmaceutica N.V. N-(4-piperidinyl)-n-phenylamides and -carbamates
US4584303A (en) * 1984-04-09 1986-04-22 The Boc Group, Inc. N-aryl-N-(4-piperidinyl)amides and pharmaceutical compositions and method employing such compounds
US5019583A (en) * 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics

Also Published As

Publication number Publication date
EP0638554A1 (en) 1995-02-15
DE69406382D1 (de) 1997-11-27
ATE159519T1 (de) 1997-11-15
DE69406382T2 (de) 1998-02-26
JP3429370B2 (ja) 2003-07-22
SG52444A1 (en) 1998-09-28
JPH07165713A (ja) 1995-06-27
EP0638554B1 (en) 1997-10-22
GR3025213T3 (en) 1998-02-27
US5599938A (en) 1997-02-04
GB9316863D0 (en) 1993-09-29
ES2109595T3 (es) 1998-01-16

Similar Documents

Publication Publication Date Title
DE69032981D1 (de) N-Heteroarylamidederivate als Inhibitoren von Acyl-Coenzym A: Cholesterol-Acyl-Transferase
BR9401484A (pt) Hidrazida de ácido 1h-indol-3-acético e formulação farmacêutica
NO981415D0 (no) Nye N-arylpiperidin-forbindelser, en fremgangsmåte ved fremstilling derav og farmasöytiske preparater inneholdende slike
BR9203919A (pt) Processo para a preparacao de uma n-(aril)-1,2,4-triazolopirimidina-2-sulfonamida
DK0638554T3 (da) Fremgangsmåde til fremstilling af et N-phenyl-N-(4-piperidinyl)amidderivat
FI960206A0 (fi) Menetelmä HIV-proteaasi-inhibiittoreiden valmistamiseksi
DK0841328T3 (da) Fremgangsmåde til fremstilling af 4-amino-1,2,4-triazoler
DK0662475T3 (da) Fremgangsmåde til fremstilling af 2-perfluoralkyl-3-oxazolin-5-on.
ES2193140T3 (es) Procedimiento para la produccion de 3-vinilcefalosporinas.
ATE161263T1 (de) 2,4-diamino-1,3,5-triazinyl-6- phosphonsäurederivate
NO20004918D0 (no) FremgangsmÕte for fremstilling av benzotiofenkarboksylsyreamidderivater
EP1298127A4 (en) AMINO ACID N-CARBOXY ANHYDRIDE WITH SUBSTITUENTS ON NITROGEN
DK0677514T3 (da) Cyclopropylderivater, fremgangsmåde til fremstilling deraf og anvendelser deraf
DE69311545D1 (de) Tetrahydrophthalimid derivate, zwischenprodukte zu deren herstellung, verfahren zur herstellung beider sowie diese als wirksame bestandteile enthaltende herbizide
ATE145395T1 (de) 5-amino-2-phenoxysulfonanilid-derivate
BR9405262A (pt) Processo para a preparação de um ácido piridina-2,3-dicarboxílico
ATE330946T1 (de) Verfahren zur herstellung einer benzylamin- verbindung
DK1052249T3 (da) Fremgangsmåde til fremstilling af hydroxamsyrer
DK1078916T3 (da) Fremgangsmåde til fremstilling af N-acylaminosyreestere og N-acylaminoacetaler