DK0608404T3 - Androst-4-en(4,5-b)pyrrolderivater og fremgangsmåde til fremstilling deraf - Google Patents
Androst-4-en(4,5-b)pyrrolderivater og fremgangsmåde til fremstilling derafInfo
- Publication number
- DK0608404T3 DK0608404T3 DK93917746.5T DK93917746T DK0608404T3 DK 0608404 T3 DK0608404 T3 DK 0608404T3 DK 93917746 T DK93917746 T DK 93917746T DK 0608404 T3 DK0608404 T3 DK 0608404T3
- Authority
- DK
- Denmark
- Prior art keywords
- androst
- ene
- preparation
- pyrrole derivatives
- hydrogen
- Prior art date
Links
- IATKKATWPOVYCC-VMXHOPILSA-N (8s,9s,10r,13s,14s)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthrene Chemical compound C1CC2=CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 IATKKATWPOVYCC-VMXHOPILSA-N 0.000 title 1
- 150000003233 pyrroles Chemical class 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
- 239000003886 aromatase inhibitor Substances 0.000 abstract 1
- 229940046844 aromatase inhibitors Drugs 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0036—Nitrogen-containing hetero ring
- C07J71/0042—Nitrogen only
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Pyrrole Compounds (AREA)
- Fats And Perfumes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929217035A GB9217035D0 (en) | 1992-08-11 | 1992-08-11 | Androst-4-eno(4,5-b)pyrrole derivatives and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0608404T3 true DK0608404T3 (da) | 1996-04-29 |
Family
ID=10720180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93917746.5T DK0608404T3 (da) | 1992-08-11 | 1993-08-05 | Androst-4-en(4,5-b)pyrrolderivater og fremgangsmåde til fremstilling deraf |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5457097A (https=) |
| EP (1) | EP0608404B1 (https=) |
| JP (1) | JPH07500119A (https=) |
| CN (1) | CN1086220A (https=) |
| AT (1) | ATE136036T1 (https=) |
| AU (1) | AU662077B2 (https=) |
| CA (1) | CA2120726A1 (https=) |
| DE (1) | DE69302007T2 (https=) |
| DK (1) | DK0608404T3 (https=) |
| ES (1) | ES2088289T3 (https=) |
| FI (1) | FI941635A0 (https=) |
| GB (1) | GB9217035D0 (https=) |
| GR (1) | GR3019729T3 (https=) |
| HU (1) | HUT67662A (https=) |
| IL (1) | IL106597A (https=) |
| MX (1) | MX9304852A (https=) |
| MY (1) | MY108957A (https=) |
| NZ (1) | NZ254805A (https=) |
| TW (1) | TW276257B (https=) |
| WO (1) | WO1994004554A1 (https=) |
| ZA (1) | ZA935769B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5510340A (en) * | 1992-06-12 | 1996-04-23 | Sri International | Antihypercholesterolemic compounds and related pharmaceutical compositions and methods of use |
| CA2794565C (en) | 2010-04-08 | 2018-08-21 | Emory University | Substituted androst-4-ene diones |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3032551A (en) * | 1961-05-25 | 1962-05-01 | Syntex Sa | Pyrrolo(3', 2'-2, 3)-androstanes and process therefor |
| US3282928A (en) * | 1964-04-23 | 1966-11-01 | American Cyanamid Co | 1, 11-iminoestratetraenes |
| GB8503940D0 (en) * | 1985-02-15 | 1985-03-20 | Erba Farmitalia | 4-substituted androstendione derivatives |
| GB8617107D0 (en) * | 1986-07-14 | 1986-08-20 | Erba Farmitalia | 6-/7-methylenandrosta-1 4-diene-3 17-dione derivatives |
| GB8622330D0 (en) * | 1986-09-17 | 1986-10-22 | Erba Farmitalia | 4-substituted 6-alkylidenandrostene-3,17-dione derivatives |
| GB8721384D0 (en) * | 1987-09-11 | 1987-10-21 | Erba Farmitalia | 17-substituted andro-sta-1 4-dien-3-one derivatives |
-
1992
- 1992-08-11 GB GB929217035A patent/GB9217035D0/en active Pending
-
1993
- 1993-07-19 US US08/092,789 patent/US5457097A/en not_active Expired - Fee Related
- 1993-08-05 ES ES93917746T patent/ES2088289T3/es not_active Expired - Lifetime
- 1993-08-05 JP JP6505839A patent/JPH07500119A/ja active Pending
- 1993-08-05 DE DE69302007T patent/DE69302007T2/de not_active Expired - Fee Related
- 1993-08-05 IL IL106597A patent/IL106597A/xx not_active IP Right Cessation
- 1993-08-05 NZ NZ254805A patent/NZ254805A/en unknown
- 1993-08-05 HU HU9401003A patent/HUT67662A/hu unknown
- 1993-08-05 CA CA002120726A patent/CA2120726A1/en not_active Abandoned
- 1993-08-05 DK DK93917746.5T patent/DK0608404T3/da active
- 1993-08-05 AT AT93917746T patent/ATE136036T1/de not_active IP Right Cessation
- 1993-08-05 EP EP93917746A patent/EP0608404B1/en not_active Expired - Lifetime
- 1993-08-05 WO PCT/EP1993/002080 patent/WO1994004554A1/en not_active Ceased
- 1993-08-05 AU AU47072/93A patent/AU662077B2/en not_active Ceased
- 1993-08-09 ZA ZA935769A patent/ZA935769B/xx unknown
- 1993-08-09 TW TW082106387A patent/TW276257B/zh active
- 1993-08-10 MX MX9304852A patent/MX9304852A/es unknown
- 1993-08-10 CN CN93109285A patent/CN1086220A/zh active Pending
- 1993-08-10 MY MYPI93001588A patent/MY108957A/en unknown
-
1994
- 1994-04-08 FI FI941635A patent/FI941635A0/fi not_active Application Discontinuation
-
1996
- 1996-04-23 GR GR960401114T patent/GR3019729T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2120726A1 (en) | 1994-03-03 |
| GB9217035D0 (en) | 1992-09-23 |
| AU4707293A (en) | 1994-03-15 |
| US5457097A (en) | 1995-10-10 |
| AU662077B2 (en) | 1995-08-17 |
| ATE136036T1 (de) | 1996-04-15 |
| EP0608404B1 (en) | 1996-03-27 |
| HU9401003D0 (en) | 1994-07-28 |
| DE69302007D1 (de) | 1996-05-02 |
| GR3019729T3 (en) | 1996-07-31 |
| FI941635A7 (fi) | 1994-04-08 |
| WO1994004554A1 (en) | 1994-03-03 |
| EP0608404A1 (en) | 1994-08-03 |
| FI941635A0 (fi) | 1994-04-08 |
| MX9304852A (es) | 1994-02-28 |
| IL106597A (en) | 1997-09-30 |
| MY108957A (en) | 1996-11-30 |
| ES2088289T3 (es) | 1996-08-01 |
| NZ254805A (en) | 1995-11-27 |
| CN1086220A (zh) | 1994-05-04 |
| IL106597A0 (en) | 1993-12-08 |
| TW276257B (https=) | 1996-05-21 |
| JPH07500119A (ja) | 1995-01-05 |
| DE69302007T2 (de) | 1996-08-29 |
| HUT67662A (en) | 1995-04-28 |
| ZA935769B (en) | 1994-03-08 |
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