DK0575442T3 - Tetracycliske imidazoquinazolinderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem - Google Patents
Tetracycliske imidazoquinazolinderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende demInfo
- Publication number
- DK0575442T3 DK0575442T3 DK92906903.7T DK92906903T DK0575442T3 DK 0575442 T3 DK0575442 T3 DK 0575442T3 DK 92906903 T DK92906903 T DK 92906903T DK 0575442 T3 DK0575442 T3 DK 0575442T3
- Authority
- DK
- Denmark
- Prior art keywords
- image
- alkyl
- processes
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- KJMFQJFNQYWQAV-UHFFFAOYSA-N 3h-imidazo[4,5-h]quinazoline Chemical class C1=NC=NC2=C(NC=N3)C3=CC=C21 KJMFQJFNQYWQAV-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- SVUOLADPCWQTTE-UHFFFAOYSA-N 1h-1,2-benzodiazepine Chemical compound N1N=CC=CC2=CC=CC=C12 SVUOLADPCWQTTE-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004849 alkoxymethyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000003474 anti-emetic effect Effects 0.000 abstract 1
- 229940125681 anticonvulsant agent Drugs 0.000 abstract 1
- 239000001961 anticonvulsive agent Substances 0.000 abstract 1
- 229940125683 antiemetic agent Drugs 0.000 abstract 1
- 239000002111 antiemetic agent Substances 0.000 abstract 1
- 239000000164 antipsychotic agent Substances 0.000 abstract 1
- 229940005529 antipsychotics Drugs 0.000 abstract 1
- 239000002249 anxiolytic agent Substances 0.000 abstract 1
- 230000000949 anxiolytic effect Effects 0.000 abstract 1
- 229940005530 anxiolytics Drugs 0.000 abstract 1
- -1 aralkoxy Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 230000003920 cognitive function Effects 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004984 dialkylaminoalkoxy group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000003326 hypnotic agent Substances 0.000 abstract 1
- 230000000147 hypnotic effect Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Lubricants (AREA)
- Eye Examination Apparatus (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK91411A DK41191D0 (da) | 1991-03-07 | 1991-03-07 | Heterocycliske forbindelser, deres fremstilling og anvendelse |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0575442T3 true DK0575442T3 (da) | 1996-05-06 |
Family
ID=8093215
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91411A DK41191D0 (da) | 1991-03-07 | 1991-03-07 | Heterocycliske forbindelser, deres fremstilling og anvendelse |
| DK92906903.7T DK0575442T3 (da) | 1991-03-07 | 1992-02-19 | Tetracycliske imidazoquinazolinderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91411A DK41191D0 (da) | 1991-03-07 | 1991-03-07 | Heterocycliske forbindelser, deres fremstilling og anvendelse |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5260298A (da) |
| EP (1) | EP0575442B1 (da) |
| JP (1) | JPH0813818B2 (da) |
| AT (1) | ATE132151T1 (da) |
| AU (1) | AU650733B2 (da) |
| CA (1) | CA2105675A1 (da) |
| DE (1) | DE69207180T2 (da) |
| DK (2) | DK41191D0 (da) |
| ES (1) | ES2082458T3 (da) |
| FI (1) | FI933878A (da) |
| GR (1) | GR3018896T3 (da) |
| IE (1) | IE920644A1 (da) |
| IL (1) | IL101046A (da) |
| NO (1) | NO933162D0 (da) |
| NZ (1) | NZ241846A (da) |
| PT (1) | PT100204A (da) |
| WO (1) | WO1992015591A1 (da) |
| ZA (1) | ZA921649B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201311B (da) * | 1991-06-17 | 1993-03-01 | Hoffmann La Roche | |
| AU4035893A (en) * | 1991-12-17 | 1993-07-19 | Upjohn Company, The | 3-substituted imidazo (1,5-a) and imidazo (1,5-a)-triazolo (1,5-c) quinoxalines and quinazolines with cns activity |
| AU6470096A (en) * | 1995-07-19 | 1997-02-18 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused triazole compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK476885D0 (da) * | 1985-10-17 | 1985-10-17 | Ferrosan As | Heterocycliske forbindelser og fremgangsmaader til fremstilling heraf |
| DK443589D0 (da) * | 1989-09-08 | 1989-09-08 | Ferrosan As | Heterocykliske forbindelser, deres fremstilling og anvendelse |
-
1991
- 1991-03-07 DK DK91411A patent/DK41191D0/da not_active Application Discontinuation
-
1992
- 1992-02-19 DK DK92906903.7T patent/DK0575442T3/da active
- 1992-02-19 WO PCT/DK1992/000050 patent/WO1992015591A1/en active IP Right Grant
- 1992-02-19 DE DE69207180T patent/DE69207180T2/de not_active Expired - Fee Related
- 1992-02-19 EP EP92906903A patent/EP0575442B1/en not_active Expired - Lifetime
- 1992-02-19 CA CA002105675A patent/CA2105675A1/en not_active Abandoned
- 1992-02-19 AT AT92906903T patent/ATE132151T1/de not_active IP Right Cessation
- 1992-02-19 ES ES92906903T patent/ES2082458T3/es not_active Expired - Lifetime
- 1992-02-19 AU AU14148/92A patent/AU650733B2/en not_active Ceased
- 1992-02-19 JP JP4506489A patent/JPH0813818B2/ja not_active Expired - Lifetime
- 1992-02-20 US US07/839,981 patent/US5260298A/en not_active Expired - Fee Related
- 1992-02-24 IL IL10104692A patent/IL101046A/en not_active IP Right Cessation
- 1992-02-28 IE IE064492A patent/IE920644A1/en not_active Application Discontinuation
- 1992-03-05 ZA ZA921649A patent/ZA921649B/xx unknown
- 1992-03-05 NZ NZ241846A patent/NZ241846A/xx unknown
- 1992-03-06 PT PT100204A patent/PT100204A/pt not_active Application Discontinuation
-
1993
- 1993-09-06 NO NO933162A patent/NO933162D0/no unknown
- 1993-09-06 FI FI933878A patent/FI933878A/fi not_active Application Discontinuation
-
1996
- 1996-02-01 GR GR960400293T patent/GR3018896T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2105675A1 (en) | 1992-09-08 |
| ATE132151T1 (de) | 1996-01-15 |
| FI933878A0 (fi) | 1993-09-06 |
| ES2082458T3 (es) | 1996-03-16 |
| EP0575442B1 (en) | 1995-12-27 |
| IL101046A (en) | 1995-10-31 |
| AU1414892A (en) | 1992-10-06 |
| EP0575442A1 (en) | 1993-12-29 |
| NZ241846A (en) | 1993-10-26 |
| DE69207180T2 (de) | 1996-06-05 |
| JPH0813818B2 (ja) | 1996-02-14 |
| NO933162D0 (no) | 1993-09-06 |
| US5260298A (en) | 1993-11-09 |
| DE69207180D1 (de) | 1996-02-08 |
| IE920644A1 (en) | 1992-09-09 |
| JPH06501488A (ja) | 1994-02-17 |
| DK41191D0 (da) | 1991-03-07 |
| ZA921649B (en) | 1992-11-25 |
| GR3018896T3 (en) | 1996-05-31 |
| PT100204A (pt) | 1993-05-31 |
| IL101046A0 (en) | 1992-11-15 |
| FI933878A (fi) | 1993-09-06 |
| WO1992015591A1 (en) | 1992-09-17 |
| AU650733B2 (en) | 1994-06-30 |
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