DK0530446T3 - Use of sulfur-containing carboxylic acids for the control of pathophysiologically conditioned excitation disorders - Google Patents

Use of sulfur-containing carboxylic acids for the control of pathophysiologically conditioned excitation disorders

Info

Publication number
DK0530446T3
DK0530446T3 DK92108825T DK92108825T DK0530446T3 DK 0530446 T3 DK0530446 T3 DK 0530446T3 DK 92108825 T DK92108825 T DK 92108825T DK 92108825 T DK92108825 T DK 92108825T DK 0530446 T3 DK0530446 T3 DK 0530446T3
Authority
DK
Denmark
Prior art keywords
disorders
pathophysiologically
sulfur
control
carboxylic acids
Prior art date
Application number
DK92108825T
Other languages
Danish (da)
Inventor
Heinz Dr Ulrich
Carl-Heinrich Dr Weischer
Helmut Dr Hettche
Juergen Prof Engel
Harald Dr Borbe
W Prof Dr Dimpfel
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Application granted granted Critical
Publication of DK0530446T3 publication Critical patent/DK0530446T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Use of compounds of the formula <IMAGE> in which X is a hydrogen atom or both Xs are a single bond between the two sulphur atoms, and n is a number from 1 to 10, or the therapeutically utilisable salts thereof for the preparation of a medicament for combating pathophysiological excitatory disorders and related diseases as well as allergic disorders, and the preparation of corresponding medicaments.
DK92108825T 1991-07-05 1992-05-26 Use of sulfur-containing carboxylic acids for the control of pathophysiologically conditioned excitation disorders DK0530446T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4122303 1991-07-05

Publications (1)

Publication Number Publication Date
DK0530446T3 true DK0530446T3 (en) 1998-09-23

Family

ID=6435517

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92108825T DK0530446T3 (en) 1991-07-05 1992-05-26 Use of sulfur-containing carboxylic acids for the control of pathophysiologically conditioned excitation disorders

Country Status (9)

Country Link
EP (1) EP0530446B1 (en)
JP (1) JPH05213745A (en)
AT (1) ATE162715T1 (en)
CA (1) CA2073084C (en)
DE (2) DE59209162D1 (en)
DK (1) DK0530446T3 (en)
ES (1) ES2112874T3 (en)
GR (1) GR3026161T3 (en)
IE (1) IE922181A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4222826A1 (en) * 1992-07-09 1994-01-13 Schering Ag Medicines to prevent tolerance development during treatment with benzodiazepine receptor-binding agents
DE4317646A1 (en) * 1993-05-27 1994-12-01 Asta Medica Ag Tablets containing thioctic acid and at least one basic component
DE4327462A1 (en) * 1993-08-16 1995-02-23 Carl Heinrich Dr Weischer N-Acetyl-p-aminophenol derivatives for controlling pain
DE4343592C2 (en) * 1993-12-21 1998-04-16 Asta Medica Ag Use of R - (+) - alpha-lipoic acid and its metabolites in the form of the free acid or as salts or esters or amides for the treatment of glucose metabolic disorders in the central nervous system
DE4433764A1 (en) 1994-09-22 1996-03-28 Asta Medica Ag Dosage forms containing alpha-lipoic acid, solid salts of R-thioctic acid with improved release and bioavailability
DE4439480C1 (en) * 1994-11-08 1996-06-05 Asta Medica Ag Use of D, L-alpha-lipoic acid and / or its enantiomers, and / or their derivatives as an additive in red cell liquid preserves for homologous and autologous erythrocyte concentrates and as an additive in erythrocyte cryoconserves for homologous and autologous erythrocyte concentrates
DE19806354B4 (en) * 1998-02-10 2004-09-16 Bdd Group Holding Ag Use of α-lipoic acid or its physiologically tolerable salts for the treatment of LDL hypercholesterolemia
US6197340B1 (en) 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
US6191162B1 (en) 1998-05-28 2001-02-20 Medical Research Institute Method of reducing serum glucose levels
US6905707B2 (en) 1998-05-28 2005-06-14 Medical Research Institute Controlled release arginine alpha ketoglutarate
EP2145883A1 (en) * 1998-10-26 2010-01-20 The Research Foundation Of The State University Of New York Dibenzyl lipoic acid derivatives and their use in treatment of disease
DE10027968A1 (en) * 2000-06-08 2001-12-13 Asta Medica Ag Adjuvant therapy of dementia using alpha-lipoic acid or derivative, is effective in combination with antidementia or neurotransmission improving agents in improving cognitive function in e.g. Alzheimer's disease patients
DE10125883A1 (en) 2001-05-28 2002-12-12 Serumwerk Bernburg Ag Medicines containing an effector of glutathione metabolism together with alpha-lipoic acid in the context of kidney replacement therapy
DE10258239A1 (en) * 2002-12-13 2004-06-24 Degussa Ag Formulation used for treating non-chronic alcoholic intoxication, contains alpha-lipoic acid for scavenging free radicals and activating alcohol metabolizing enzymes
DE10303229B4 (en) * 2003-01-28 2007-07-26 Keyneurotek Ag Ambroxol and Angiotensin Converting Enzyme (ACE) inhibitors Drugs and their use in the treatment of neurodegenerative diseases
JP4716666B2 (en) * 2003-05-21 2011-07-06 有限会社オガ リサーチ α-Lipoic acid-containing aqueous preparation
RU2423117C2 (en) * 2003-07-02 2011-07-10 Сергей Михайлович Зенович Medication for reducing rate of progressing, prevention of development, prevention of onset of pathological processes induced by intake of ethanol and/or substances possessing addictive potential
CN100422134C (en) * 2004-03-12 2008-10-01 北京天衡药物研究院 2-(alpha-n-pentanone) phenmethyl and its preparation process and application
JP2006321732A (en) * 2005-05-18 2006-11-30 Fancl Corp Removal of abnormal protein, and composition for suppressing increase of 8-hydroxy-2'-deoxyguanosine
US8278358B2 (en) * 2006-07-06 2012-10-02 Omnica Gmbh Lipoic acid derivatives
DE102007038849A1 (en) 2007-08-16 2009-02-19 Adscil Gmbh Use of R (+) - alpha lipoic acid for the treatment of cryptogenic neuropathy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2038733T3 (en) * 1987-12-04 1993-08-01 Asta Medica Ag PROCEDURE FOR PREPARING AN INJECTABLE SOLUTION OF THIOCTIC ACID SALT WITH THROMETHANOL AND / OR BASIC AMINO ACIDS.
LU87834A1 (en) * 1989-11-09 1991-05-07 Asta Pharma Ag MEDICINAL PRODUCTS CONTAINING CARBONIC ACIDS CONTAINING SULFUR AS A ACTIVE SUBSTANCE AND THE USE THEREOF FOR CONTROLLING RETROVIRUS

Also Published As

Publication number Publication date
ATE162715T1 (en) 1998-02-15
GR3026161T3 (en) 1998-05-29
CA2073084C (en) 2002-10-22
EP0530446A2 (en) 1993-03-10
DE59209162D1 (en) 1998-03-05
CA2073084A1 (en) 1993-01-06
EP0530446A3 (en) 1993-04-28
DE4220851A1 (en) 1993-01-07
EP0530446B1 (en) 1998-01-28
ES2112874T3 (en) 1998-04-16
JPH05213745A (en) 1993-08-24
IE922181A1 (en) 1993-01-13

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