DK0512415T3 - Fremgangsmåde til enantioselektiv syntese af 2(R)-benzylravsyremonoamidderivater - Google Patents
Fremgangsmåde til enantioselektiv syntese af 2(R)-benzylravsyremonoamidderivaterInfo
- Publication number
- DK0512415T3 DK0512415T3 DK92107395.3T DK92107395T DK0512415T3 DK 0512415 T3 DK0512415 T3 DK 0512415T3 DK 92107395 T DK92107395 T DK 92107395T DK 0512415 T3 DK0512415 T3 DK 0512415T3
- Authority
- DK
- Denmark
- Prior art keywords
- succinic acid
- acid monoamide
- enantioselective synthesis
- benzyl succinic
- monoamide derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
- C07F15/0013—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
- C07F15/0073—Rhodium compounds
- C07F15/008—Rhodium compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4114401 | 1991-05-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0512415T3 true DK0512415T3 (da) | 1998-03-09 |
Family
ID=6430862
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92107395.3T DK0512415T3 (da) | 1991-05-03 | 1992-04-30 | Fremgangsmåde til enantioselektiv syntese af 2(R)-benzylravsyremonoamidderivater |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5321139A (da) |
| EP (1) | EP0512415B1 (da) |
| JP (1) | JPH05170718A (da) |
| AT (1) | ATE156477T1 (da) |
| DE (1) | DE59208769D1 (da) |
| DK (1) | DK0512415T3 (da) |
| ES (1) | ES2106104T3 (da) |
| GR (1) | GR3024926T3 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0512416B1 (de) * | 1991-05-03 | 1997-01-08 | Hoechst Aktiengesellschaft | Neue homochirale Diphosphine |
| US6743921B2 (en) * | 2002-01-24 | 2004-06-01 | Dsm Catalytica Pharmaceuticals, Inc. | Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds |
| JP4918257B2 (ja) * | 2005-12-27 | 2012-04-18 | キッセイ薬品工業株式会社 | 不斉還元方法 |
| CN101973926B (zh) * | 2010-11-05 | 2012-09-19 | 威海迪素制药有限公司 | R-米格列奈钙的制备方法 |
| CN111253244B (zh) * | 2020-03-10 | 2020-10-16 | 山东铂源药业有限公司 | 一种(s)-2-苄基琥珀酸拆分母液的回收利用方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4008281A (en) * | 1973-12-03 | 1977-02-15 | Monsanto Company | Asymmetric catalysis |
| DD253947A1 (de) * | 1986-11-28 | 1988-02-10 | Akad Wissenschaften Ddr | Verfahren zur herstellung chiraler uebergangsmetallkomplexkatalysatoren |
| JPH0222244A (ja) * | 1988-07-09 | 1990-01-25 | Fuji Yakuhin Kogyo Kk | 光学活性化合物の製造方法 |
| JPH02157243A (ja) * | 1988-12-09 | 1990-06-18 | Kissei Pharmaceut Co Ltd | 光学活性（ｒ）−２−（１−ナフチルメチル）コハク酸の製造方法 |
| ES2086341T3 (es) * | 1989-09-12 | 1996-07-01 | Hoechst Ag | Derivados de aminoacidos con propiedades inhibidoras de la renina, procedimiento para su preparacion, agentes que los contienen y su utilizacion. |
-
1992
- 1992-04-30 AT AT92107395T patent/ATE156477T1/de active
- 1992-04-30 EP EP92107395A patent/EP0512415B1/de not_active Expired - Lifetime
- 1992-04-30 DE DE59208769T patent/DE59208769D1/de not_active Expired - Fee Related
- 1992-04-30 ES ES92107395T patent/ES2106104T3/es not_active Expired - Lifetime
- 1992-04-30 DK DK92107395.3T patent/DK0512415T3/da active
- 1992-05-01 JP JP4112518A patent/JPH05170718A/ja active Pending
-
1993
- 1993-02-16 US US08/022,887 patent/US5321139A/en not_active Expired - Fee Related
-
1997
- 1997-10-03 GR GR970402567T patent/GR3024926T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2106104T3 (es) | 1997-11-01 |
| DE59208769D1 (de) | 1997-09-11 |
| ATE156477T1 (de) | 1997-08-15 |
| US5321139A (en) | 1994-06-14 |
| EP0512415A3 (en) | 1993-03-03 |
| GR3024926T3 (en) | 1998-01-30 |
| EP0512415A2 (de) | 1992-11-11 |
| EP0512415B1 (de) | 1997-08-06 |
| JPH05170718A (ja) | 1993-07-09 |
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