DK0503561T3 - Fremgangsmåde til fremstilling af diastereoselektiv reduktiv pinakol-kobling af homochirale alfa-aminoaldehyder - Google Patents

Fremgangsmåde til fremstilling af diastereoselektiv reduktiv pinakol-kobling af homochirale alfa-aminoaldehyder

Info

Publication number
DK0503561T3
DK0503561T3 DK92104085T DK92104085T DK0503561T3 DK 0503561 T3 DK0503561 T3 DK 0503561T3 DK 92104085 T DK92104085 T DK 92104085T DK 92104085 T DK92104085 T DK 92104085T DK 0503561 T3 DK0503561 T3 DK 0503561T3
Authority
DK
Denmark
Prior art keywords
preparation
amino aldehydes
pinacol coupling
diastereoselective
homochiral
Prior art date
Application number
DK92104085T
Other languages
Danish (da)
English (en)
Inventor
Joachim-Heiner Dr Jendralla
Detlef Dr Jacobi
Bernhard Dr Kammermeier
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4122911A external-priority patent/DE4122911A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of DK0503561T3 publication Critical patent/DK0503561T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Lubricants (AREA)
DK92104085T 1991-03-15 1992-03-10 Fremgangsmåde til fremstilling af diastereoselektiv reduktiv pinakol-kobling af homochirale alfa-aminoaldehyder DK0503561T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4108357 1991-03-15
DE4122911A DE4122911A1 (de) 1991-07-11 1991-07-11 Verfahren zur diastereoselektiven reduktiven pinakol-kupplung von homochiralen (alpha)-aminoaldehyden

Publications (1)

Publication Number Publication Date
DK0503561T3 true DK0503561T3 (da) 1999-07-05

Family

ID=25901877

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92104085T DK0503561T3 (da) 1991-03-15 1992-03-10 Fremgangsmåde til fremstilling af diastereoselektiv reduktiv pinakol-kobling af homochirale alfa-aminoaldehyder

Country Status (16)

Country Link
US (1) US5519113A (es)
EP (1) EP0503561B1 (es)
JP (1) JP3254238B2 (es)
KR (1) KR920018013A (es)
AT (1) ATE172713T1 (es)
AU (1) AU664696B2 (es)
CA (1) CA2063013A1 (es)
CS (1) CS76792A3 (es)
DE (1) DE59209540D1 (es)
DK (1) DK0503561T3 (es)
ES (1) ES2124710T3 (es)
FI (1) FI921069A (es)
HU (1) HUT62851A (es)
IE (1) IE920828A1 (es)
MX (1) MX9201116A (es)
NO (1) NO920984L (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362912A (en) * 1989-05-23 1994-11-08 Abbott Laboratories Process for the preparation of a substituted diaminodiol
PT1064298E (pt) 1998-03-19 2009-01-02 Vertex Pharma Inibidores de caspasas
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
WO2003068242A1 (en) * 2002-02-11 2003-08-21 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
CN1980658A (zh) * 2004-05-27 2007-06-13 沃泰克斯药物股份有限公司 治疗自身炎性疾病的ice抑制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142056A (en) * 1989-05-23 1992-08-25 Abbott Laboratories Retroviral protease inhibiting compounds
AU8205491A (en) * 1990-06-01 1991-12-31 Du Pont Merck Pharmaceutical Company, The 1,4-diamino-2,3-dihydroxybutanes
HU9203505D0 (en) * 1990-06-01 1993-01-28 Du Pont Merck Pharma 1,4-diamino-2,3-dihydroxi-butane compounds

Also Published As

Publication number Publication date
KR920018013A (ko) 1992-10-21
ES2124710T3 (es) 1999-02-16
HUT62851A (en) 1993-06-28
AU664696B2 (en) 1995-11-30
EP0503561A3 (en) 1993-05-05
AU1284092A (en) 1992-09-17
FI921069A0 (fi) 1992-03-12
NO920984L (no) 1992-09-16
ATE172713T1 (de) 1998-11-15
FI921069A (fi) 1992-09-16
JPH0578290A (ja) 1993-03-30
EP0503561B1 (de) 1998-10-28
HU9200864D0 (en) 1992-05-28
US5519113A (en) 1996-05-21
JP3254238B2 (ja) 2002-02-04
CA2063013A1 (en) 1992-09-16
CS76792A3 (en) 1992-10-14
IE920828A1 (en) 1992-09-23
DE59209540D1 (de) 1998-12-03
MX9201116A (es) 1992-10-01
EP0503561A2 (de) 1992-09-16
NO920984D0 (no) 1992-03-13

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