DK0439059T3 - 1-phenylalkyl-3-phenylurinstofderivat - Google Patents
1-phenylalkyl-3-phenylurinstofderivatInfo
- Publication number
- DK0439059T3 DK0439059T3 DK91100515.5T DK91100515T DK0439059T3 DK 0439059 T3 DK0439059 T3 DK 0439059T3 DK 91100515 T DK91100515 T DK 91100515T DK 0439059 T3 DK0439059 T3 DK 0439059T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenylalkyl
- integer
- alkyl
- phenylurea derivative
- alkoxyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1223590 | 1990-01-22 | ||
JP2876890 | 1990-02-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0439059T3 true DK0439059T3 (da) | 1994-12-19 |
Family
ID=26347808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK91100515.5T DK0439059T3 (da) | 1990-01-22 | 1991-01-17 | 1-phenylalkyl-3-phenylurinstofderivat |
Country Status (10)
Country | Link |
---|---|
US (1) | US5202351A (fr) |
EP (1) | EP0439059B1 (fr) |
JP (1) | JPH05310678A (fr) |
KR (1) | KR910014366A (fr) |
AT (1) | ATE110375T1 (fr) |
AU (1) | AU636946B2 (fr) |
CA (1) | CA2034673A1 (fr) |
DE (1) | DE69103535T2 (fr) |
DK (1) | DK0439059T3 (fr) |
ES (1) | ES2057608T3 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL100915A (en) * | 1991-02-19 | 1996-03-31 | Erba Carlo Spa | Double-transformed urea and theories, their preparation and pharmaceutical preparations containing them |
WO1993024458A1 (fr) * | 1992-05-28 | 1993-12-09 | Pfizer Inc. | Nouveau derives n-aryle et de n-heteroaryluree en tant qu'inhibiteurs de l'acylcoenzime a: cholesterol acyltransferase (acat) |
CA2107196A1 (fr) * | 1992-09-29 | 1994-03-30 | Mitsubishi Chemical Corporation | Derives de carboxamide |
US5534529A (en) * | 1993-06-30 | 1996-07-09 | Sankyo Company, Limited | Substituted aromatic amides and ureas derivatives having anti-hypercholesteremic activity, their preparation and their therapeutic uses |
US6133326A (en) | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
HUP9602538A3 (en) | 1995-09-18 | 1997-08-28 | Sankyo Co | New urea and amide derivatives having acat inhibitory activity, their preparation and their use |
CA2190041A1 (fr) * | 1995-11-13 | 1997-05-14 | Shinya Inoue | Derives de l'uree |
GEP20043286B (en) * | 2000-02-02 | 2004-07-26 | Warner Lambert Co | Dual Inhibitors of Cholesteryl Ester and Wax Ester Synthesis for Sebaceous Gland Disorders |
CA2551056A1 (fr) | 2003-11-07 | 2005-05-19 | F. Hoffmann-La Roche Ag | Derives de benzo [b][1,4] dioxepine |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2485600A (en) * | 1946-04-01 | 1949-10-25 | Harold W Moburg | Derivatives of safrol and isosafrol |
FR6183M (fr) * | 1967-03-10 | 1968-07-15 | ||
US4102673A (en) * | 1971-06-21 | 1978-07-25 | Hercules Incorporated | 1-Phenyl-hexyl ureas as herbicides |
JPS5312844A (en) * | 1976-07-20 | 1978-02-04 | Nippon Tokushu Noyaku Seizo Kk | Nn44halogenobenzyllnnmethyl*or nonsubstitutedd*cycloalkylln**phenylurea or thiourea compounds* their preparation and fungicides containing the same as active constituents |
DE2928485A1 (de) * | 1979-07-14 | 1981-01-29 | Bayer Ag | Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen |
US4473579A (en) * | 1982-01-26 | 1984-09-25 | American Cyanamid Company | Antiatherosclerotic tetrasubstituted ureas and thioureas |
US4868210A (en) * | 1988-03-30 | 1989-09-19 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic compounds and compositions |
DE68911203T2 (de) * | 1988-03-30 | 1994-04-14 | Warner Lambert Co | N-[[(2,6-disubstituierte)phenyl]N'- arylalkyl] Harnstoffe als antihypercholesterolemische und antiatherosclerotische Mittel. |
IL89997A0 (en) * | 1988-04-25 | 1989-12-15 | Lilly Co Eli | Propanamine derivatives |
JPH02124884A (ja) * | 1988-07-08 | 1990-05-14 | Zhongguo Yixuekexueyuan Yaowo Yanjiusuo | N―置換アミド誘導体 |
CA2010184A1 (fr) * | 1989-02-17 | 1990-08-17 | Bharat K. Trivedi | Composes d'uree trisubstitues ayant des proprietes antihyperlipidemiques et antiatherosclerotiques |
AU629376B2 (en) * | 1989-08-04 | 1992-10-01 | Mitsubishi Chemical Corporation | 1-phenylalkyl-3-phenylurea derivatives |
-
1991
- 1991-01-14 JP JP3002821A patent/JPH05310678A/ja active Pending
- 1991-01-17 EP EP91100515A patent/EP0439059B1/fr not_active Expired - Lifetime
- 1991-01-17 ES ES91100515T patent/ES2057608T3/es not_active Expired - Lifetime
- 1991-01-17 AT AT91100515T patent/ATE110375T1/de active
- 1991-01-17 DE DE69103535T patent/DE69103535T2/de not_active Expired - Fee Related
- 1991-01-17 DK DK91100515.5T patent/DK0439059T3/da active
- 1991-01-18 AU AU69482/91A patent/AU636946B2/en not_active Ceased
- 1991-01-21 KR KR1019910001093A patent/KR910014366A/ko not_active Application Discontinuation
- 1991-01-21 CA CA002034673A patent/CA2034673A1/fr not_active Abandoned
- 1991-01-22 US US07/643,983 patent/US5202351A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2034673A1 (fr) | 1991-07-23 |
ATE110375T1 (de) | 1994-09-15 |
ES2057608T3 (es) | 1994-10-16 |
DE69103535D1 (de) | 1994-09-29 |
EP0439059A3 (en) | 1991-11-13 |
AU636946B2 (en) | 1993-05-13 |
DE69103535T2 (de) | 1995-01-26 |
EP0439059A2 (fr) | 1991-07-31 |
US5202351A (en) | 1993-04-13 |
KR910014366A (ko) | 1991-08-31 |
JPH05310678A (ja) | 1993-11-22 |
AU6948291A (en) | 1991-07-25 |
EP0439059B1 (fr) | 1994-08-24 |
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