DE957877C - Device for treating blood, blood plasma or the like with oxygen and optionally with ultraviolet light - Google Patents

Description

ISSUED FEBRUARY 7, 1957

The invention is based on the known devices for treating blood od. Like. In which oxygen is introduced into the blood to form blood foam. In the case of the previously known devices of this type, the main emphasis is on bubbling oxygen through the blood to be treated placed, whereby a blood foam is created above the level of the blood. This foam was previously viewed as an undesirable by-product and was used in one of the well-known cases broken again by special treatment and returned to the perfused blood. Even In another previously known case, the foam is returned to the blood that has not yet been foamed, since the foam is only discharged by mixing with this blood is possible. The invention now proceeds from in none of the Prior publications indicated that the foam is the most intense oxygen-treated part of the blood, because only in the foam is the blood so finely divided that the Oxygen to the same extent that the blood can absorb in the lungs. In the known devices, this is why this broom

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This whit foam intensively treated with oxygen is lost in its full effect, because it can only communicate with the rest of the body by pervading oxygen, i. H. less intensely treated blood is mixed.

Building on this, value is attached to the invention that just the foam as the am The treated part of the blood is not returned to the liquid blood of the treatment room, but is transferred as such into another container. The device is therefore according to the invention so constructed that there are two separate rooms for untreated 'and treated blood and a Has conduit system through which the treated blood from the one space in the upper area of the other, whereby the oxygen is introduced into the blood of one space It becomes that the blood flows into the other room exclusively as blood foam.

In detail, this can be done in the device according to the invention

ao manure can be achieved in that the pipeline system extends down to the floor level of one room includes immersing tube, in which in the area of its «lower end the oxygen introduction so ends in that the blood foam formed only there

as rises in the pipe.

Based on the further knowledge of the inventor that the treatment of the blood with ultraviolet light in the state of the foam is much more effective than this, for example happens in a previously known case within a capillary is a development of the invention provided that a UV irradiation lamp for the known UV irradiation of blood on the Place of passage of the blood foam from one room to another is provided.

The foam formation is also used to exclusively promote the blood, which also in thirdly, a very significant advantage over the known devices is achieved. Select

4 "rend with all these previously known facilities any pumps must be used, this is not the subject of the invention Case. The conveyance of blood by pumps contradicts the more recent knowledge, according to which

* 5 this kept in a completely tension-free state Must be to hemolysis of the blood to avoid destroying the red blood cells and the patient provided with such blood due to kidney damage with fatal outcome can get sick. The fact that in the subject matter of the invention only the blood foam through his own buoyancy is promoted, because it is caused by the constant foam formation on the foot ■ the conduit is carried upwards, it is possible to keep the blood in a completely tension-free state from the treatment site to the. Forward collecting space for treated blood.

In the drawing, an exemplary embodiment of the subject matter of the invention is shown schematically.

Show in it

Fig. Ι and 2 a schematic view of the entire apparatus for the treatment and delivery of treated blood,

Fig. 3 shows a vertical section through the device for treating the blood and Fig. 4 is a section along the line HI-III of

Fig · 3-

On a mobile table 1, two oxygen bottles 2 are attached under the tray, which contain the oxygen that is to be introduced into the blood to be treated. The oxygen is brought from the cylinder via a reducing 2 ₀ in the supporting tubes 3 from which it can be removed _fc at various draw stub 3 "Mittes rubber hoses. 3 The aim of arranging two bottles is to always have a spare bottle on hand. On the columns 3 attached to the table τ, two devices for treating the blood are fixed, which are marked with 4 l. You can put on the mobile table 1 next to the patient's bed and on the columns 3 z. B. be pivoted over the arm of the latter.

One of the devices mentioned for treating the blood is shown in FIG. 3 in a vertical section. This device comprises two juxtaposed, fused vessels 5, 6, of which one, 5, serves to receive the untreated blood , while the vessel 6 is intended to store treated blood . A line 7 through which untreated blood flows into the vessel 5 opens. A line 3, coming from the oxygen bottles, is connected to the connector 8, in which a check valve 9 is installed. A sequence is designated by 10. In the interior of the vessel 5 is a riser pipe 11 ang'ebracM, Ίϊτϊ an.

its upper linden tree into one: i'nchter 12 shaped is. The riser pipe 11 passes through: i the inclined surface 13, which is supported at 14 on projections of the inner wall of the vessel and which protrudes into the vessel 6. This riser pipe 11 can, for. B. also with the mentioned Surface 13 should be fused into one piece. At least one projection 15 secures the Flat 13 against sliding.

The vessel 6 is provided at its lower end with a drain port 16, one of which Line 17 leads to the patient to be treated. In this rubber line or in the vessel 6 can oxygen can also be supplied, with which the trade is carried out Blood is kept in constant motion and the sedimentation processes are avoided (Fig. 1). In the line 17 are one behind the other Clamping screw 18, a drop counter 19, a glass grain filter 2O, an air valve 21 and a vein needle 22 connected.

Above the two vessels 5 and 6, both of which are provided with scales 23 indicating the contents, there is a hood 24 in which a UV radiator, for example a quartz gravure burner 25, is installed. Below the burner, but above the vessels 5, 6, there is a quartz wall 26 to close off the latter against the entry of air. The power supply line for the burner is designated by 27. A holder 28 for sterile gauze is provided between the hoods 24 and 26 and the outer wall of the vessels 5, 6.

see who fills the room 29 and the penetration of aerobics from the atmospheric Air prevents. The same purpose could of course also be achieved by a sanded cover will. The burner can also be used as an isolated piece of equipment, i.e. H. without a permanent connection with the Find quartz hood 26, use, so that this hood 26, with a corresponding all-round seal provided at the bottom, the device can seal against the outside air.

The bescbrielK-nc device works as follows: Unbchandcltes blood or also blood plasma is introduced through the line 7 into the vessel 5, the pressure reducing valve arranged on the oxygen bottle 2 is opened and oxygen is introduced through the nozzle SS via the pipe tap. In the ascending pipe 11, which ends at a distance from the lower end of the vessel 5 and which consequently fills its lower part with Bhit, is

so the latter mixed with SaueTstott, whereby standing Schauni slides form, which allow an absolute saturation of the hat with oxygen. A blood foam emerges from the funnel-shaped upper end 12 and is now on the inclined surface 13

»5 irradiated by the UV lamps, and optionally sterilize the water in this case WiTdT mt ^- T ^ Cr UV lamp is developed a TicTTTruekbrenner which no heat and a radiation area from 1800 to 2600 A. The treated blood foam then drips from the surface 13 into the vessel 6, where it collapses again to form blood fluid. The oxygen can escape through a line (not shown), which is also protected from the entry of air by sterile gauze. The device described allows the blood to be circulated The latter can be filled as often as desired after removal from the nozzle: 6 again through line 7 into the vessel 5 and the treatment can thus be repeated.
As shown, two devices 4 are arranged on one and the same table so that there is no interruption in the treatment even in the event of incidents.

In the hoods 24 and 26 could also, for. B. against the upper end 12 of the riser pipe 11 Directional oxygen inlets should be provided in order to prevent excessive foam formation.

A pump or the like can also be provided

be to the blood in a closed circuit from the vessel 6 through the patient's body

So bring uikI back to the vessel 5 ziu. Through this it is possible to normalize or increase the oxygen content of the blood.

In an analogous manner, it is possible to pour the blood emerging from the vessel into the blood one or more times Returned vessel 5 and thus to achieve a multiple circulation of the blood.

The device described can also be used in blood transfusion by donating blood Freed from carbonic acid by the oxygen treatment and at the same time irradiated with UV rays and, if necessary, sterilized.

While FIG. 1 schematically illustrates the injection of purified blood plasma introduced into the device or blood directly filled in from a blood donor, FIG. 2 shows how the blood of a patient can be circulated directly through the device. By means of the second device, foreign blood can also be fed to the same patient, as shown in dotted lines.

Claims (8)

Patent claims: 1. Device for treating blood or the like, in which the oxygen is introduced into the blood with the formation of blood foam, characterized in that the device has two separate rooms (5 and 6) for untreated and treated blood and a line system (11 , 12, 13), through which the treated blood from one room ( 5) to the upper area of the other, (6), is conducted, the introduction (8) of the oxygen into one room (5) as follows it is provided that the blood passes into the other space exclusively as blood foam. 2. Apparatus according to claim 1, characterized in that the line system is immersed in a room (fi) up to the ground level. ' Tube (ii') includes, in the im. In the area of its lower end, the oxygen inlet ( ft) opens in such a way that the blood foam formed only there rises in the tube. 3. Apparatus according to claim 1 and 2, characterized in that the tube (11) with its upper end penetrates a drainage plate (13) so that the blood foam conveyed through the tube, spreading on the plate, drains into the other space. 4. Apparatus according to claim 1, characterized in that a UV irradiation lamp (25) for the per se known UV irradiation of blood at the point where the blood foam crosses over from one room (5) to the other, (6), is provided. 5. Apparatus according to claim 1 to 4, characterized in that the UV irradiation lamp is arranged so that it irradiates the foam spread on the drainage plate (13). 6. Apparatus according to claim 4 or 5, characterized in that the UV irradiation lamp consists of a quartz rotogravure burner. 7. Apparatus according to claim 1 to 3, characterized by the blood foam on the drainage plate (13) blowing oxygen supplies. 8. Apparatus according to claim 1 or one of the following, characterized in that it consists of Glass is made. Considered publications:
German Patent No. 818399;
French patent specification No. 989821. For this purpose ι sheet of drawings O Μ »$ 77/32 7.56 «09 782 1.57)