DE9414868U1 - Vascular embolization particles - Google Patents
Vascular embolization particlesInfo
- Publication number
- DE9414868U1 DE9414868U1 DE9414868U DE9414868U DE9414868U1 DE 9414868 U1 DE9414868 U1 DE 9414868U1 DE 9414868 U DE9414868 U DE 9414868U DE 9414868 U DE9414868 U DE 9414868U DE 9414868 U1 DE9414868 U1 DE 9414868U1
- Authority
- DE
- Germany
- Prior art keywords
- vascular embolization
- particles
- embolization particles
- vascular
- radiopaque
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002245 particle Substances 0.000 title claims description 8
- 230000010102 embolization Effects 0.000 title claims description 4
- 230000002792 vascular Effects 0.000 title claims description 3
- 239000000126 substance Substances 0.000 claims description 2
- 229920003023 plastic Polymers 0.000 description 5
- 230000003073 embolic effect Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 3
- 230000007556 vascular defect Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000002872 contrast media Substances 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229940039231 contrast media Drugs 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- JJJFUHOGVZWXNQ-UHFFFAOYSA-N enbucrilate Chemical group CCCCOC(=O)C(=C)C#N JJJFUHOGVZWXNQ-UHFFFAOYSA-N 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 230000004807 localization Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000003106 tissue adhesive Substances 0.000 description 1
- 229940075469 tissue adhesives Drugs 0.000 description 1
- 201000011531 vascular cancer Diseases 0.000 description 1
- 206010055031 vascular neoplasm Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Gefäßdefekte können zu Blutverlusten oder fehlerhafter Blutverteilung mit Beeinträchtigung der SauerstoffVersorgung fuhren. Diese Defekte durch Einbringung Drahtspiralen, Gewebekleber, Ballons und Kunststoffteilchen verschlossen, 'embolisiert', werden.Vascular defects can lead to blood loss or incorrect blood distribution with impaired oxygen supply. These defects are closed, 'embolized', by inserting wire spirals, tissue adhesives, balloons and plastic particles.
Hierzu wird nach Punktion eines Gefäßes, meist in der Leistenregion, ein Katheter unmittlebar vor dem Gefäßdefekt plaziert. Über diesen wird das Embolisat injiziert, welches zum Verschluß des Gefäßdefektes fuhrt. Von großer Bedeutung für das Gelingen der Embolisation ist die Lokalisation des Embolisates durch Darstellung im Röntgendurchleuchtungsbild. Nur durch korrekte Plazierung ist der Behandlungserfolg gewährleistet, eine Fehlplazierung kann Schäden verursachen.For this, after puncturing a vessel, usually in the groin region, a catheter is placed directly in front of the vascular defect. The embolic material is injected through this, which leads to the closure of the vascular defect. The localization of the embolic material by visualizing it in the X-ray image is of great importance for the success of the embolization. The success of the treatment can only be guaranteed if it is placed correctly; incorrect placement can cause damage.
Festkörper wie Metallspiralen sind in der Regel röntgendicht. Kleber wie z.B. Histoacryl werden durch Mischung mit Kontrastmittel (z.B. Lipiodol) röntgendicht gemacht. Die häufig verwendeten Kunststoffpartikel (z.B. Polyvinylalkohol), die zum Verschluß kleiner Gefäßäste, z.B. in Gefäßtumoren, Verwendung finden, sind nicht im Röntgenbild lokalisierbar.Solid bodies such as metal spirals are usually radiopaque. Adhesives such as Histoacryl are made radiopaque by mixing them with contrast media (e.g. Lipiodol). The frequently used plastic particles (e.g. polyvinyl alcohol) that are used to close small vascular branches, e.g. in vascular tumors, cannot be localized in the X-ray image.
Aufgabe:Task:
Durch Beimischung röntgendichter Substanzen, z.B. Jod, soll die Darstellbarkeit der Kunststoffpartikel (Embolisat) im Röntgenbild erzielt werden.By adding radiopaque substances, e.g. iodine, the plastic particles (embolic material) can be visualized in the X-ray image.
Vorteile:Advantages:
Mit der Erfindung wird erreicht, daß die Kunststoffpartikel im Röntgenbild sichtbar sind und eine Kontrolle der Plazierung gewährleistet ist. Dies fuhrt zu einer Vereinfachung und höheren Sicherheit der angiographischen Embolisation.The invention ensures that the plastic particles are visible in the X-ray image and that control of their placement is ensured. This simplifies and increases the safety of angiographic embolization.
1. Mischen einer Vinylalkoholmonomerlösung mit jodhaltigem Kontrastmittel in einer Konzentration von 100 mgJ/cm3 1. Mixing a vinyl alcohol monomer solution with iodine-containing contrast medium at a concentration of 100 mgJ/cm 3
2. Polymerisation2. Polymerization
3. Zerkleinerung des Kunsstoflkörpers (Mahlen)3. Crushing of the plastic body (grinding)
4. Herstellen einer Menge von Partikeln gleicher Größe (100, 250, 500, 1000 &mgr;&pgr;&agr;).4. Prepare a quantity of particles of equal size (100, 250, 500, 1000 μπα).
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9414868U DE9414868U1 (en) | 1994-09-13 | 1994-09-13 | Vascular embolization particles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE9414868U DE9414868U1 (en) | 1994-09-13 | 1994-09-13 | Vascular embolization particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE9414868U1 true DE9414868U1 (en) | 1994-12-15 |
Family
ID=6913647
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE9414868U Expired - Lifetime DE9414868U1 (en) | 1994-09-13 | 1994-09-13 | Vascular embolization particles |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE9414868U1 (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003084582A1 (en) * | 2002-03-29 | 2003-10-16 | Boston Scientific Limited | Embolization |
| US7858183B2 (en) | 2005-03-02 | 2010-12-28 | Boston Scientific Scimed, Inc. | Particles |
| WO2011003902A2 (en) | 2009-07-07 | 2011-01-13 | Soenke Bartling | Multimodal visible polymer embolization material |
| US8012454B2 (en) | 2002-08-30 | 2011-09-06 | Boston Scientific Scimed, Inc. | Embolization |
| US8216612B2 (en) | 2004-03-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Embolization |
-
1994
- 1994-09-13 DE DE9414868U patent/DE9414868U1/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003084582A1 (en) * | 2002-03-29 | 2003-10-16 | Boston Scientific Limited | Embolization |
| US8012454B2 (en) | 2002-08-30 | 2011-09-06 | Boston Scientific Scimed, Inc. | Embolization |
| US8216612B2 (en) | 2004-03-02 | 2012-07-10 | Boston Scientific Scimed, Inc. | Embolization |
| US7858183B2 (en) | 2005-03-02 | 2010-12-28 | Boston Scientific Scimed, Inc. | Particles |
| WO2011003902A2 (en) | 2009-07-07 | 2011-01-13 | Soenke Bartling | Multimodal visible polymer embolization material |
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