DE9400863U1 - Anti-osteoporotic mixture - Google Patents
Anti-osteoporotic mixtureInfo
- Publication number
- DE9400863U1 DE9400863U1 DE9400863U DE9400863U DE9400863U1 DE 9400863 U1 DE9400863 U1 DE 9400863U1 DE 9400863 U DE9400863 U DE 9400863U DE 9400863 U DE9400863 U DE 9400863U DE 9400863 U1 DE9400863 U1 DE 9400863U1
- Authority
- DE
- Germany
- Prior art keywords
- vitamin
- dose
- proline
- amino acids
- antiosteoporotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title claims description 10
- 230000003262 anti-osteoporosis Effects 0.000 title claims description 9
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 40
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 11
- 229930003268 Vitamin C Natural products 0.000 claims description 11
- 150000001413 amino acids Chemical class 0.000 claims description 11
- 235000019154 vitamin C Nutrition 0.000 claims description 11
- 239000011718 vitamin C Substances 0.000 claims description 11
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 10
- 239000004472 Lysine Substances 0.000 claims description 10
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims description 10
- 230000004097 bone metabolism Effects 0.000 claims description 10
- 229930003944 flavone Natural products 0.000 claims description 10
- 150000002213 flavones Chemical class 0.000 claims description 10
- 235000011949 flavones Nutrition 0.000 claims description 10
- 235000010323 ascorbic acid Nutrition 0.000 claims description 9
- 239000011668 ascorbic acid Substances 0.000 claims description 9
- 229960005070 ascorbic acid Drugs 0.000 claims description 9
- 229910052500 inorganic mineral Inorganic materials 0.000 claims description 9
- 239000011707 mineral Substances 0.000 claims description 9
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 8
- 239000011575 calcium Substances 0.000 claims description 8
- 229910052791 calcium Inorganic materials 0.000 claims description 8
- 235000015872 dietary supplement Nutrition 0.000 claims description 8
- 229930003935 flavonoid Natural products 0.000 claims description 8
- 150000002215 flavonoids Chemical class 0.000 claims description 8
- 235000017173 flavonoids Nutrition 0.000 claims description 8
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 7
- 239000011777 magnesium Substances 0.000 claims description 7
- 229910052749 magnesium Inorganic materials 0.000 claims description 7
- 230000000087 stabilizing effect Effects 0.000 claims description 7
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 6
- 150000003839 salts Chemical class 0.000 claims description 6
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims 5
- 235000005282 vitamin D3 Nutrition 0.000 claims 5
- 239000011647 vitamin D3 Substances 0.000 claims 5
- 229940021056 vitamin d3 Drugs 0.000 claims 5
- MHJAJDCZWVHCPF-UHFFFAOYSA-L dimagnesium phosphate Chemical compound [Mg+2].OP([O-])([O-])=O MHJAJDCZWVHCPF-UHFFFAOYSA-L 0.000 claims 1
- 229910000395 dimagnesium phosphate Inorganic materials 0.000 claims 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims 1
- 229910000396 dipotassium phosphate Inorganic materials 0.000 claims 1
- 235000019797 dipotassium phosphate Nutrition 0.000 claims 1
- 235000013373 food additive Nutrition 0.000 claims 1
- 239000002778 food additive Substances 0.000 claims 1
- 235000010755 mineral Nutrition 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000011737 fluorine Substances 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000010703 silicon Substances 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 102000055006 Calcitonin Human genes 0.000 description 1
- 108060001064 Calcitonin Proteins 0.000 description 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 229930003316 Vitamin D Natural products 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 description 1
- 229960004015 calcitonin Drugs 0.000 description 1
- 235000020776 essential amino acid Nutrition 0.000 description 1
- 239000003797 essential amino acid Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 231100000508 hormonal effect Toxicity 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 235000013930 proline Nutrition 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Description
Antiosteoporotische Mischung enthaltend Flavone oder u Flayonoide, Vitamin C oder Ascorbinsäure, die Aminosäuren Lysin, Prolin, die Mineralsalze Kalzium und/oder Magnesium mit und ohne Vitamin D, mit und ohne Phosphor zur Stabilisierung des Knochenstoffwechsels als NahrungsmittelzusatzAntiosteoporotic mixture containing flavones or flayonoids , vitamin C or ascorbic acid, the amino acids lysine, proline, the mineral salts calcium and/or magnesium with and without vitamin D, with and without phosphorus for the stabilization of bone metabolism as a food supplement
Hintergrund:Background:
Die bisher üblichen, den Knochenstoffwechsel prophylaktisch oder therapeutisch angehenden Nahrungsmittelzusätze berücksichtigen lediglich die anorganischen Stoffe, die in der Nahrung fur den Knochen wichtig sind. Die physiologischen Bedingungen des Knochenstoffwechsels sind jedoch komplexer. So hat es sich gezeigt, da der Knochen, um überhaupt fähig zu sein, angebotene Minerale stabilisierend aufzunehmen, dazu eines aus Aminosäuren bestehenden Fasergerustes bedarf, welches er aus essentiellen Stoffen aufbauen mu . Dies sind Stoffe, die er sich nicht selbst herstellen kann. Im einzelnen:The usual food supplements that have been used to prevent or treat bone metabolism only take into account the inorganic substances in food that are important for bones. However, the physiological conditions of bone metabolism are more complex. It has been shown that in order to be able to absorb minerals in a stabilizing manner, bones need a fiber structure made up of amino acids, which they must build up from essential substances. These are substances that they cannot produce themselves. In detail:
Die essentielle Aminosäure Lysin, die Aminosäure Prolin, das Vitamin C oder die Ascorbinsäure. In der Natur kommt das Vitamin C so gut wie immer in der pflanzlichen Nahrung in Kombination mit Flavonen und/oder Flavonoiden vor. Unter der Anregung von katalytisch wirksamen Peptiden, denen eine Hormonwirkung zugesprochen wird, wie dem Kalzitonin, fangt sich die organische Matrix des Knochens die folgenden Minerale ein: Kalzium, Magnesium, Phosphate, die Spurenelemente Silicium, Fluor und Kupfer. Davon ausgehend wird eine geeignete Mischung vorgestellt, enthaltend:The essential amino acid lysine, the amino acid proline, vitamin C or ascorbic acid. In nature, vitamin C is almost always found in plant foods in combination with flavones and/or flavonoids. Under the stimulation of catalytically active peptides, which are said to have a hormonal effect, such as calcitonin, the organic matrix of the bone captures the following minerals: calcium, magnesium, phosphates, the trace elements silicon, fluorine and copper. Based on this, a suitable mixture is presented, containing:
10 - 1000 mg Flavone, im Durchschnitt 200 mg 10 - 1000 mg Vitamin C,/im Durchschnitt 100 mg10 - 1000 mg flavones, on average 200 mg 10 - 1000 mg vitamin C, / on average 100 mg
10 - 1000 mg der Aminosäuren Lysin und Prolin, im Durchschnitt 100 mg10 - 1000 mg of the amino acids lysine and proline, on average 100 mg
10 - 1000 mg der.Minerale Kalzium oder Magnesium, im Durchschnitt 200 mg10 - 1000 mg of the minerals calcium or magnesium, on average 200 mg
Aus resorptiven Gründen enthalt das Präparat niemals gemeinsam Kalzium und Magnesium, sondern es gibt es in einer kalzium- und einer magnesiumhaltigen Version. Beide Versionen können die knochenrelevanten Spurenelemente Kupfer, Silicium und Fluor in homoeopatlscher Dosis enthalten.For absorption reasons, the preparation never contains calcium and magnesium together, but is available in a calcium and a magnesium-containing version. Both versions can contain the bone-relevant trace elements copper, silicon and fluorine in homoeopathic doses.
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE9400863U DE9400863U1 (en) | 1994-01-19 | 1994-01-19 | Anti-osteoporotic mixture |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE9400863U DE9400863U1 (en) | 1994-01-19 | 1994-01-19 | Anti-osteoporotic mixture |
Publications (1)
Publication Number | Publication Date |
---|---|
DE9400863U1 true DE9400863U1 (en) | 1994-04-14 |
Family
ID=6903420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE9400863U Expired - Lifetime DE9400863U1 (en) | 1994-01-19 | 1994-01-19 | Anti-osteoporotic mixture |
Country Status (1)
Country | Link |
---|---|
DE (1) | DE9400863U1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1340428A2 (en) * | 1997-11-24 | 2003-09-03 | Bristol-Myers Squibb Company | Fortified confectionery and methods of preparation thereof |
US7655264B2 (en) | 1997-08-29 | 2010-02-02 | Mcneil-Ppc, Inc. | Process for promoting calcium absorption |
-
1994
- 1994-01-19 DE DE9400863U patent/DE9400863U1/en not_active Expired - Lifetime
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7655264B2 (en) | 1997-08-29 | 2010-02-02 | Mcneil-Ppc, Inc. | Process for promoting calcium absorption |
EP1340428A2 (en) * | 1997-11-24 | 2003-09-03 | Bristol-Myers Squibb Company | Fortified confectionery and methods of preparation thereof |
EP1340428A3 (en) * | 1997-11-24 | 2005-03-02 | Bristol-Myers Squibb Company | Fortified confectionery and methods of preparation thereof |
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