DE69940524D1 - Abbildungssystem zum nachweis von fluoreszierenden organischen substanzen in einer probe - Google Patents

Abbildungssystem zum nachweis von fluoreszierenden organischen substanzen in einer probe

Info

Publication number
DE69940524D1
DE69940524D1 DE69940524T DE69940524T DE69940524D1 DE 69940524 D1 DE69940524 D1 DE 69940524D1 DE 69940524 T DE69940524 T DE 69940524T DE 69940524 T DE69940524 T DE 69940524T DE 69940524 D1 DE69940524 D1 DE 69940524D1
Authority
DE
Germany
Prior art keywords
sample
organic substances
fluorescent organic
detecting fluorescent
illustration system
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69940524T
Other languages
German (de)
English (en)
Inventor
Charles L Mcglynn
Prasad R Akkapeddi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Raytheon Co
Original Assignee
Raytheon Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Raytheon Co filed Critical Raytheon Co
Application granted granted Critical
Publication of DE69940524D1 publication Critical patent/DE69940524D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69940524T 1999-11-09 1999-11-09 Abbildungssystem zum nachweis von fluoreszierenden organischen substanzen in einer probe Expired - Lifetime DE69940524D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1999/026542 WO2001035078A1 (en) 1999-11-09 1999-11-09 Method and apparatus for performing cell analysis based on simultaneous multiple marker emissions from neoplasia (casmmen)

Publications (1)

Publication Number Publication Date
DE69940524D1 true DE69940524D1 (de) 2009-04-16

Family

ID=22274028

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69940524T Expired - Lifetime DE69940524D1 (de) 1999-11-09 1999-11-09 Abbildungssystem zum nachweis von fluoreszierenden organischen substanzen in einer probe

Country Status (4)

Country Link
EP (1) EP1147400B1 (enExample)
JP (1) JP4536986B2 (enExample)
DE (1) DE69940524D1 (enExample)
WO (1) WO2001035078A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5563405B2 (ja) * 2010-08-24 2014-07-30 荏原実業株式会社 分光画像取得装置及び方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8623494D0 (en) * 1986-09-30 1986-11-05 Mackay C D Assay technique
JPH0694526A (ja) * 1990-12-28 1994-04-05 Nec Corp 光パルス発生方法および装置ならびに時間分解分光装置
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US5817462A (en) * 1995-02-21 1998-10-06 Applied Spectral Imaging Method for simultaneous detection of multiple fluorophores for in situ hybridization and multicolor chromosome painting and banding
DE4136769A1 (de) * 1991-11-05 1993-05-06 Humboldt-Universitaet Zu Berlin, O-1086 Berlin, De Verfahren zum diagnostizieren von mit fluoreszierenden substanzen angereicherten, insbesondere tumoroesen gewebebereichen
FR2694193B1 (fr) * 1992-07-28 1994-10-28 Abraxas Bio Labs Sa Méthode de cytodiagnostic utilisant l'alstonine comme marqueur sélectif et kit de diagnostic contenant ce marqueur.
WO1994003470A1 (en) * 1992-08-10 1994-02-17 Davies Richard J Method and apparatus for screening and diagnosing for cancers
FI93781C (fi) * 1993-03-18 1995-05-26 Wallac Oy Biospesifinen multiparametrinen määritysmenetelmä
DE19634873A1 (de) * 1996-08-29 1998-03-12 Boehringer Mannheim Gmbh System zur Unterscheidung fluoreszierender Molekülgruppen durch zeitaufgelöste Fluoreszenzmessung
GB9704054D0 (en) * 1997-02-27 1997-04-16 Univ Cambridge Tech Assay
US5986271A (en) * 1997-07-03 1999-11-16 Lazarev; Victor Fluorescence imaging system
DE69730030T2 (de) * 1997-11-17 2005-07-21 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Konfokales Spektroskopiesystem und -verfahren

Also Published As

Publication number Publication date
WO2001035078A1 (en) 2001-05-17
EP1147400B1 (en) 2009-03-04
EP1147400A1 (en) 2001-10-24
JP2003514222A (ja) 2003-04-15
JP4536986B2 (ja) 2010-09-01

Similar Documents

Publication Publication Date Title
DE60027711D1 (de) Verbesserte vorrichtung zum nachweis von myokardischämie
DE69840657D1 (de) Verfahren zum Nachweis eines Restanalyts in einer Probe
DE60223635D1 (de) Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten
DE60029876D1 (de) Verfahren und Oligonukleotide zum Nachweis von Nukleinsäuresequenzvariationen
IL147038A0 (en) Genomic profiling: a rapid method for testing a complex biological sample for the presence of many types of organisms
DE69535882D1 (de) Fluoreszenztest zum nachweis der spaltung einer nukleinsäure
FI19992451A7 (fi) Sovitelma ja menetelmä näyteputkien käsittelemiseksi laboratoriossa
EP1329717A4 (en) Reagent and method for detecting substance
DE60140804D1 (de) Neue nukleinsäuresonden und verfahren zum testen von nukleinsäuren unter deren verwendung
DE50014134D1 (de) Verfahren zur erkennung von signalfehlern
DE60136324D1 (de) Vorrichtung zum auswerten biologischer informationen
DE60138486D1 (de) Verfahren zum nachweis von liganden
DE60021503D1 (de) Destillationsverfahren für leicht polymerisierbare Substanzen enthaltende Lösungen
EP1332331A4 (en) INTERFEROMETRIC SENSOR AND METHOD FOR DETECTING OPTICAL FIELDS
DE69909611D1 (de) Reagenz zum nachweis von singulett-sauerstoff
DE69533026D1 (de) Verfahren zum testen von bodenproben auf organische verschmutzung
DE50111035D1 (de) Verfahren zur detektion des von einer probe kommenden lichtes
DE69535747D1 (de) Medium zum Nachweis bestimmter Mikroben in einer Probe
DE50004301D1 (de) Vorrichtung zur zerkleinerung von organischen substanzen
ATE219139T1 (de) Gerät zum nachweis von mikroorganismen in einer probe
ATE234464T1 (de) Verfarhung zum bestimmung flüssigen konzentration
DE50001880D1 (de) Verfahren zum vermessen von einer handhabungsvorrichtung
DE60039030D1 (de) Verfahren zum nachweis von unter anaerobischen bedingungen kultivierten bakterien
ATA217099A (de) Verfahren zur detektion und quantifizierung von nukleinsäuren in einer probe
ATE393236T1 (de) Medium zum nachweis bestimmter mikroben in einer probe

Legal Events

Date Code Title Description
8364 No opposition during term of opposition